Biomedical Research Education & Training
Faculty Member

Stone, Michael P., Ph.D.
Professor of Chemistry
Professor of Biochemistry

Lab Url: N/A

Phone Number: 615-322-2589

Email Address:

Stone, Michael's picture
Academic history
B.S., University of California, Davis
Ph.D., University of California, Irvine
Post-Doctoral, The University of Rochester

Office Address   Mailing Address

5524 Stevenson Center

VU Station B 351822

Banerjee, S, Christov, PP, Kozekova, A, Rizzo, CJ, Egli, M, Stone, MP. Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem Res Toxicol, 25(2), 422-35, 2012 PMCID:3285121

Huang, H, Das, RS, Basu, AK, Stone, MP. Structures of (5''S)-8,5''-Cyclo-2''-deoxyguanosine Mismatched with dA or dT. Chem Res Toxicol, 25(2), 478-90, 2012 PMCID:3285119

Banerjee, S, Brown, KL, Egli, M, Stone, MP. Bypass of aflatoxin B1 adducts by the Sulfolobus solfataricus DNA polymerase IV. J Am Chem Soc, 133(32), 12556-68, 2011 PMCID:3154525

Huang, H, Das, RS, Basu, AK, Stone, MP. Structure of (5''S)-8,5''-cyclo-2''-deoxyguanosine in DNA. J Am Chem Soc, 133(50), 20357-68, 2011 PMCID:3285119

Huang, H, Wang, H, Kozekova, A, Rizzo, CJ, Stone, MP. Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct. J Am Chem Soc, 133(40), 16101-10, 2011 PMCID:3187658

Huang, H, Wang, H, Voehler, MW, Kozekova, A, Rizzo, CJ, McCullough, AK, Lloyd, RS, Stone, MP. I?-Hydroxy-1,N2-propano-2''-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage. Chem Res Toxicol, 24(7), 1123-33, 2011 PMCID:3138414

Kowal, EA, Ganguly, M, Pallan, PS, Marky, LA, Gold, B, Egli, M, Stone, MP. Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2''-deoxyadenosine:dT base pairing in DNA. J Phys Chem B, 115(47), 13925-34, 2011 PMCID:3225014

Shanmugam, G, Kozekov, ID, Guengerich, FP, Rizzo, CJ, Stone, MP. 1,N2-Etheno-2''-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine. Chem Res Toxicol, 24(7), 1071-9, 2011 PMCID:3138413

Stone, MP, Huang, H, Brown, KL, Shanmugam, G. Chemistry and structural biology of DNA damage and biological consequences. Chem Biodivers, 8(9), 1571-615, 2011 PMCID:3225014

Brown, KL, Roginskaya, M, Zou, Y, Altamirano, A, Basu, AK, Stone, MP. Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5''-GTgG-3'' sequence: destabilization of two base pairs at the lesion site. Nucleic Acids Res, 38(2), 428-40, 2010 PMCID:2811006

Christov, PP, Banerjee, S, Stone, MP, Rizzo, CJ. Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. J Nucleic Acids, 2010, 2010 PMCID:2925382

Christov, PP, Chowdhury, G, Garmendia, CA, Wang, F, Stover, JS, Elmquist, CE, Kozekova, A, Angel, KC, Turesky, RJ, Stone, MP, Guengerich, FP, Rizzo, CJ. The C8-2''-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Chem Res Toxicol, 23(6), 1076-88, 2010 PMCID:2891123

Christov, PP, Petrova, KV, Shanmugam, G, Kozekov, ID, Kozekova, A, Guengerich, FP, Stone, MP, Rizzo, CJ. Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2''-deoxyguanosine and 1,N2-etheno-2''-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Chem Res Toxicol, 23(8), 1330-41, 2010 PMCID:2922457

Huang, H, Kozekov, ID, Kozekova, A, Rizzo, CJ, McCullough, AK, Lloyd, RS, Stone, MP. Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage. Biochemistry, 49(29), 6155-64, 2010 PMCID:2907095

Huang, H, Kozekov, ID, Kozekova, A, Wang, H, Lloyd, RS, Rizzo, CJ, Stone, MP. DNA cross-link induced by trans-4-hydroxynonenal. Environ Mol Mutagen, 51(6), 625-34, 2010 PMCID:3140422

Shanmugam, G, Kozekov, ID, Guengerich, FP, Rizzo, CJ, Stone, MP. Structure of the 1,N(2)-etheno-2''-deoxyguanosine lesion in the 3''-G(epsilon dG)T-5'' sequence opposite a one-base deletion. Biochemistry, 49(12), 2615-26, 2010 PMCID:2844103

Brown, KL, Basu, AK, Stone, MP. The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. Biochemistry, 48(41), 9722-33, 2009 PMCID:2761728

Brown, KL, Voehler, MW, Magee, SM, Harris, CM, Harris, TM, Stone, MP. Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA. J Am Chem Soc, 131(44), 16096-107, 2009 PMCID:2773149

Huang, H, Dooley, PA, Harris, CM, Harris, TM, Stone, MP. Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5''-CpG-3'' and 5''-GpC-3'' sequence contexts. Chem Res Toxicol, 22(11), 1810-6, 2009 PMCID:2778138

Huang, H, Kim, HY, Kozekov, ID, Cho, YJ, Wang, H, Kozekova, A, Harris, TM, Rizzo, CJ, Stone, MP. Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2''-deoxyguanosine adduct in the 5''-CpG-3'' DNA sequence. J Am Chem Soc, 131(24), 8416-24, 2009 PMCID:2753404

Postdoctoral Position Available

Postdoctoral Position Details

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