Biomedical Research Education & Training
Faculty Member

Holt, Ginger E., M.D.
Associate Professor of Orthopaedic Surgery and Rehabilitation

Lab Url: N/A

Phone Number: 615-343-8612

Email Address: ginger.e.holt@vanderbilt.edu

Holt, Ginger's picture
Academic history
B.S., Univ of Alabama at Birmingham
M.D., Univ of Alabama
Residency- Orthopedic Surgery, Vanderbilt University Medical Center
Fellowship- Musculoskeletal Oncology, University of Toronto/Mt. Sinai Hospital
Fellowship-Adult Reconstruction, Colorado Joint Replacement

Office Address   Mailing Address

Medical Center East, South Tower, Suite 4200

Medical Center East, South Tower, Suite 4200 37232-8774


Research Keywords
tissue engineering, cancer biology

Patient Care Specialty
orthopaedic oncology, joint replacement, adult reconstruction

Clinical Interests
Dr. Holt joined the Vanderbilt Orthopaedic Institute in 2003. Her Clinical interests include tissue engineering and cancer biology. Dr. Holt received her BS at the University of Alabama at Birmingham, graduating magna cum laude with honors in biology research. She received her MD from the University of Alabama School of Medicine in 1996. Her Orthopaedic residency was completed at Vanderbilt Medical School in 2001 after which she completed a fellowship in Orthopaedic Oncology at the University of Toronto/Mt. Sinai Hospital and a fellowship in Adult Reconstruction Surgery in 2003 in Denver, Colorado.

Dr. Holt joined the Vanderbilt Orthopaedic Institute in 2003. Her Clinical interests include tissue engineering and cancer biology.  Dr. Holt received her BS at the University of Alabama at Birmingham, graduating magna cum laude with honors in biology research. She received her MD from the University of Alabama School of Medicine in 1996. Her Orthopaedic residency was completed at Vanderbilt Medical School in 2001 after which she completed a fellowship in Orthopaedic Oncology at the University of Toronto/Mt. Sinai Hospital and a fellowship in Adult Reconstruction Surgery in 2003 in Denver, Colorado.

Publications
Cates, JM, Friedman, DB, Seeley, EH, Dupont, WD, Schwartz, HS, Holt, GE, Caprioli, RM, Young, PP. Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis. Int J Exp Pathol, 91(4), 335-49, 2010

Crosby, SN, Polkowski, GG, Schwartz, HS, Shinar, AA, Holt, GE. Metal-Backed Versus All-Polyethylene Tibias in Megaprostheses of the Distal Femur. J Arthroplasty, 2010

Dobbs, MD, Lowas, SR, Hernanz-Schulman, M, Holt, GE, Yu, C, Kan, JH. Impact of abdominopelvic CT on Ewing sarcoma management. Acad Radiol, 17(10), 1288-91, 2010

Dumas, JE, Davis, T, Holt, GE, Yoshii, T, Perrien, DS, Nyman, JS, Boyce, T, Guelcher, SA. Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit. Acta Biomater, 6(7), 2394-406, 2010

Mansour, AA, Kelley, MC, Hatmaker, AR, Holt, GE, Schwartz, HS. Verification of musculoskeletal FDG-PET-CT findings performed for melanoma staging. Ann Surg Oncol, 17(4), 1144-51, 2010

Adelani, MA, Stover, DG, Halpern, JL, Schwartz, HS, Holt, GE. Caveat arthroplasty. J Arthroplasty, 24(5), 728-34, 2009 PMCID:2745595

Giannico, G, Holt, GE, Homlar, KC, Johnson, J, Pinnt, J, Bridge, JA. Osteoblastoma characterized by a three-way translocation: report of a case and review of the literature. Cancer Genet Cytogenet, 195(2), 168-71, 2009

Herceg, ME, Tsiatis, AC, Halpern, JL, Holt, GE, Schwartz, HS, Keedy, VL, Cates, JM. Cyclooxygenase 2 expression in soft tissue leiomyosarcoma. Anticancer Res, 29(8), 2913-7, 2009 PMCID:2745595

Holt, GE, Christie, MJ, Schwartz, HS. Trabecular metal endoprosthetic limb salvage reconstruction of the lower limb. J Arthroplasty, 24(7), 1079-85, 2009 PMCID:2745595

Thiolloy, S, Halpern, J, Holt, GE, Schwartz, HS, Mundy, GR, Matrisian, LM, Lynch, CC. Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis. Cancer Res, 69(16), 6747-55, 2009 PMCID:2745595

Adelani, MA, Wupperman, RM, Holt, GE. Benign synovial disorders. J Am Acad Orthop Surg, 16(5), 268-75, 2008

Butler, MA, Holt, GE, Crosby, SN, Weikert, DR. Late posterior interosseous nerve palsy associated with loosening of radial head implant. J Shoulder Elbow Surg, 18(6), e17-21, 2008 PMCID:2745595

Holt, GE, Halpern, JL, Lynch, CC, Devin, CJ, Schwartz, HS. Imaging Analysis of the In vivo Bioreactor: A Preliminary Study. Clin Orthop Relat Res, 2008 PMCID:2584254

Adelani, MA, Holt, GE, Dittus, RS, Passman, MA, Schwartz, HS. Revascularization after segmental resection of lower extremity soft tissue sarcomas. J Surg Oncol, 95(6), 455-60, 2007

Devin, C, Chong, PY, Holt, GE, Feurer, I, Gonzalez, A, Merchant, N, Schwartz, HS. Level-adjusted perioperative risk of sacral amputations. J Surg Oncol, 94(3), 203-11, 2006

Halpern, J, Lynch, CC, Fleming, J, Hamming, D, Martin, MD, Schwartz, HS, Matrisian, LM, Holt, GE. The application of a murine bone bioreactor as a model of tumor: bone interaction. Clin Exp Metastasis, 23(7-8), 345-56, 2006

Holt, GE, Schwartz, HS, Caldwell, RL. Proteomic profiling in musculoskeletal oncology by MALDI mass spectrometry. Clin Orthop Relat Res, 450, 105-10, 2006

Holt, GE, Thomson, AB, Griffin, AM, Bell, R, Wunder, J, Rougraff, B, Schwartz, HS. Multifocality and multifocal postradiation sarcomas. Clin Orthop Relat Res, 450, 67-75, 2006

Holt, GE, Griffin, AM, Pintilie, M, Wunder, JS, Catton, C, O'Sullivan, B, Bell, RS. Fractures following radiotherapy and limb-salvage surgery for lower extremity soft-tissue sarcomas. A comparison of high-dose and low-dose radiotherapy. J Bone Joint Surg Am, 87(2), 315-9, 2005

Holt, GE, Halpern, JL, Dovan, TT, Hamming, D, Schwartz, HS. Evolution of an in vivo bioreactor. J Orthop Res, 23(4), 916-23, 2005

Holt, GE, Dennis, DA. Use of custom triflanged acetabular components in revision total hip arthroplasty. Clin Orthop Relat Res(429), 209-14, 2004

Holt, GE, Dennis, DA. The role of patellar resurfacing in total knee arthroplasty. Clin Orthop Relat Res(416), 76-83, 2003

Holt, GE, McCarty, EC. Anterior hip dislocation with an associated vascular injury requiring amputation. J Trauma, 55(1), 135-8, 2003

Holt, GE, Mencio, GA. Pelvic C-clamp in a pediatric patient. J Orthop Trauma, 17(7), 525-7, 2003

Garth WP, DiChristina DG, Holt GE. Chronic Patellofemoral Instability Treated By Proximal Anatomical Repair and Distal Realignment. Clin Orthop(377), 132-144, 2000

Holt GE, Feurer ID, Schwartz HS. An Analysis of Concordance among Hospital Databases and Physician Records.. Annals of Surgical Oncology, 6(5), 553-6, 1998


Postdoctoral Position Available
N/A

Postdoctoral Position Details
N/A

Updated Date
04/18/2011