Biomedical Research Education & Training
Faculty Member

Estrada, Lourdes, Ph.D.
Assistant Professor of Cancer Biology

Lab Url: N/A

Phone Number: 615-936-2869

Email Address:

Estrada, Lourdes's picture
Academic history
Ph.D., University of Michigan
M.S., University of Michigan
B.S., University of Puerto Rico

Office Address   Mailing Address

446A Preston Research Building

446 PRB 2220 Pierce Avenue 6840

Research Keywords
Mathematical modeling Cancer invasion and metastasis Cancer systems biology,Apoptosis,Cancer,Cell cycle,Mouse

Research Specialty
Mathematical modeling of cancer progression

Anderson, AR, Hassanein, M, Branch, KM, Lu, J, Lobdell, NA, Maier, J, Basanta, D, Weidow, B, Narasanna, A, Arteaga, CL, Reynolds, AB, Quaranta, V, Estrada, L, Weaver, AM. Microenvironmental independence associated with tumor progression. Cancer Res, 69(22), 8797-806, 2009

Kam, Y, Karperien, A, Weidow, B, Estrada, L, Anderson, AR, Quaranta, V. Nest expansion assay: a cancer systems biology approach to in vitro invasion measurements. BMC Res Notes, 2, 130, 2009 PMCID:2716356

Enderling, H, Alexander, NR, Clark, ES, Branch, KM, Estrada, L, Crooke, C, Jourquin, J, Lobdell, N, Zaman, MH, Guelcher, SA, Anderson, AR, Weaver, AM. Dependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence. Biophys J, 95(5), 2203-18, 2008 PMCID:2517013

Georgescu, W, Jourquin, J, Estrada, L, Anderson, AR, Quaranta, V, Wikswo, JP. Model-controlled hydrodynamic focusing to generate multiple overlapping gradients of surface-immobilized proteins in microfluidic devices. Lab Chip, 8(2), 238-44, 2008 PMCID:2491634

Kam, Y, Guess, C, Estrada, L, Weidow, B, Quaranta, V. A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro. BMC Cancer, 8, 198, 2008 PMCID:2491634

Hou, P, Estrada, L, Kinley, AW, Parsons, JT, Vojtek, AB, Gorski, JL. Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hum Mol Genet, 12(16), 1981-93, 2003

Estrada, L, Caron, E, Gorski, JL. Fgd1, the Cdc42 guanine nucleotide exchange factor responsible for faciogenital dysplasia, is localized to the subcortical actin cytoskeleton and Golgi membrane. Hum Mol Genet, 10(5), 485-95, 2001

Gao, J, Estrada, L, Cho, S, Ellis, RE, Gorski, JL. The Caenorhabditis elegans homolog of FGD1, the human Cdc42 GEF gene responsible for faciogenital dysplasia, is critical for excretory cell morphogenesis. Hum Mol Genet, 10(26), 3049-62, 2001

Estrada, L, Kanelakis, KC, Levy, GN, Weber, WW. Tissue- and gender-specific expression of N-acetyltransferase 2 (Nat2*) during development of the outbred mouse strain CD-1. Drug Metab Dispos, 28(2), 139-46, 2000

Gorski, JL, Estrada, L, Hu, C, Liu, Z. Skeletal-specific expression of Fgd1 during bone formation and skeletal defects in faciogenital dysplasia (FGDY; Aarskog syndrome). Dev Dyn, 218(4), 573-86, 2000

Morishima, Y, Kanelakis, KC, Silverstein, AM, Dittmar, KD, Estrada, L, Pratt, WB. The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. J Biol Chem, 275(10), 6894-900, 2000

Estrada-Rodgers, L, Levy, GN, Weber, WW. Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells. Drug Metab Dispos, 26(5), 502-5, 1998

Estrada-Rodgers, L, Levy, GN, Weber, WW. Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter. Gene Expr, 7(1), 13-24, 1998

Garc?-a-Arrar?!s, JE, Estrada-Rodgers, L, Santiago, R, Torres, II, D?-az-Miranda, L, Torres-Avill?!n, I. Cellular mechanisms of intestine regeneration in the sea cucumber, Holothuria glaberrima Selenka (Holothuroidea:Echinodermata). J Exp Zool, 281(4), 288-304, 1998

Levy, GN, Rodgers, L, Weber, WW. Effects of heredity on response to drugs and environmental chemicals: construction of rodent models. Chem Res Toxicol, 9(8), 1215-24, 1996

Postdoctoral Position Available

Postdoctoral Position Details

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