Biomedical Research Education & Training
Faculty Member

Cates, Justin M. M., M.D., Ph.D.
Associate Professor of Pathology, Microbiology and Immunology

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Phone Number: 615-322-3234

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Cates, Justin's picture
Academic history
B.S., Tufts University
M.D., Tufts University
Ph.D., Tufts University
Residency, Massachusetts General Hospital
Fellowship, Massachusetts General Hospital

Office Address   Mailing Address

Medical Center North C2310-C

Department of Pathology C-3322 MCN Vanderbilt University Medical Center 37232

Research Keywords
Bone and soft tissue tumors; Sarcoma,Pathology,Proteomics

Clinical Research Keywords
Orthopedic pathology; soft tissue tumors

Patient Care Specialty
Diagnostic surgical and autopsy pathology

Clinical Research Description
Pathology and molecular diagnostics of bone and soft tissue tumors

Clinical Interests
Pathology of bone and soft tissue tumors
General surgical and autopsy pathology

Cole, HA, Yuasa, M, Hawley, G, Cates, JM, Nyman, JS, Schoenecker, JG. Differential development of the distal and proximal femoral epiphysis and physis in mice. Bone, 52(1), 337-46, 2013

McClain, CM, Friedman, DB, Hajri, T, Coffin, CM, Cates, JM. Predicting dedifferentiation in liposarcoma: a proteomic approach. Virchows Arch, 463(1), 85-92, 2013

Pruitt, FL, He, Y, Franco, OE, Jiang, M, Cates, JM, Hayward, SW. Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. Prostate, 73(5), 476-88, 2013

Strand, DW, DeGraff, DJ, Jiang, M, Sameni, M, Franco, OE, Love, HD, Hayward, WJ, Lin-Tsai, O, Wang, AY, Cates, JM, Sloane, BF, Matusik, RJ, Hayward, SW. Deficiency in metabolic regulators PPAR?? and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration. Am J Pathol, 182(2), 449-59, 2013

Cates, JM, Black, J, Wolfe, CC, Shinohara, ET, Holt, GE, Keedy, VL, Hande, KR, Homlar, KC, Halpern, JL, Schwartz, HS, Troutman, A, Coffin, CM. Morphologic and immunophenotypic analysis of desmoid-type fibromatosis after radiation therapy. Hum Pathol, 43(9), 1418-24, 2012

Cates, JM, Black, JO, Itani, DM, Fasig, JH, Keedy, VL, Hande, KR, Whited, BW, Homlar, KC, Halpern, JL, Holt, GE, Schwartz, HS, Coffin, CM. Signal transduction pathway analysis in fibromatosis: receptor and nonreceptor tyrosine kinases. Hum Pathol, 43(10), 1711-8, 2012

Cates, JM, Coffin, CM. Neurogenic tumors of soft tissue. Pediatr Dev Pathol, 15(1 Suppl), 62-107, 2012

Cates, JM, Coffin, CM. Extraskeletal cartilaginous, osseous, and chordoid tumors in children and adolescents. Pediatr Dev Pathol, 15(1 Suppl), 255-66, 2012

DeGraff, DJ, Clark, PE, Cates, JM, Yamashita, H, Robinson, VL, Yu, X, Smolkin, ME, Chang, SS, Cookson, MS, Herrick, MK, Shariat, SF, Steinberg, GD, Frierson, HF, Wu, XR, Theodorescu, D, Matusik, RJ. Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation. PLoS One, 7(5), e36669, 2012

Gehrie, EA, Cates, JM, Nian, H, Olson, SJ, Young, PP. Blood Group A antigen expression on cardiac endothelium is highly individualized: possible implications for transplantation. Cardiovasc Pathol, 22(4), 251-6, 2012

Ichikawa, J, Cole, HA, Magnussen, RA, Mignemi, NA, Butler, M, Holt, GE, O''Rear, L, Yuasa, M, Pabla, B, Haro, H, Cates, JM, Hamm, HE, Schwartz, HS, Schoenecker, JG. Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: procoagulant nature of osteosarcoma. Cancer, 118(9), 2494-506, 2012

Kallen, ME, Nunes Rosado, FG, Gonzalez, AL, Sanders, ME, Cates, JM. Occasional staining for p63 in malignant vascular tumors: a potential diagnostic pitfall. Pathol Oncol Res, 18(1), 97-100, 2012

Kallen, ME, Sanders, ME, Gonzalez, AL, Black, JO, Keedy, VL, Hande, KR, Homlar, KC, Halpern, JL, Holt, GE, Schwartz, HS, Coffin, CM, Cates, JM. Nuclear p63 expression in osteoblastic tumors. Tumour Biol, 33(5), 1639-44, 2012

Mignemi, NA, Itani, DM, Fasig, JH, Keedy, VL, Hande, KR, Whited, BW, Homlar, KC, Correa, H, Coffin, CM, Black, JO, Yi, Y, Halpern, JL, Holt, GE, Schwartz, HS, Schoenecker, JG, Cates, JM. Signal transduction pathway analysis in desmoid-type fibromatosis: transforming growth factor-??, COX2 and sex steroid receptors. Cancer Sci, 103(12), 2173-80, 2012

Rosado, FG, Itani, DM, Coffin, CM, Cates, JM. Utility of immunohistochemical staining with FLI1, D2-40, CD31, and CD34 in the diagnosis of acquired immunodeficiency syndrome-related and non-acquired immunodeficiency syndrome-related Kaposi sarcoma. Arch Pathol Lab Med, 136(3), 301-4, 2012

Degraff, DJ, Cates, JM, Mauney, JR, Clark, PE, Matusik, RJ, Adam, RM. When urothelial differentiation pathways go wrong: Implications for bladder cancer development and progression. Urol Oncol, 2011

Polosukhin, VV, Cates, JM, Lawson, WE, Milstone, AP, Matafonov, AG, Massion, PP, Lee, JW, Randell, SH, Blackwell, TS. Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. J Pathol, 224(2), 203-11, 2011

Polosukhin, VV, Cates, JM, Lawson, WE, Zaynagetdinov, R, Milstone, AP, Massion, PP, Ocak, S, Ware, LB, Lee, JW, Bowler, RP, Kononov, AV, Randell, SH, Blackwell, TS. Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 184(3), 317-27, 2011

Cates, JM, Friedman, DB, Seeley, EH, Dupont, WD, Schwartz, HS, Holt, GE, Caprioli, RM, Young, PP. Proteomic analysis of osteogenic sarcoma: association of tumour necrosis factor with poor prognosis. Int J Exp Pathol, 2010

Sommer, J, Itani, DM, Homlar, KC, Keedy, VL, Halpern, JL, Holt, GE, Schwartz, HS, Coffin, CM, Kelley, MJ, Cates, JM. Methylthioadenosine phosphorylase and activated insulin-like growth factor-1 receptor/insulin receptor: potential therapeutic targets in chordoma. J Pathol, 220(5), 608-17, 2010

Tatsas, AD, Keedy, VL, Florell, SR, Simpson, JF, Coffin, CM, Kelley, MC, Cates, JM. Foamy cell angiosarcoma: a rare and deceptively bland variant of cutaneous angiosarcoma. J Cutan Pathol, 2010

Adelani, MA, Schultenover, SJ, Holt, GE, Cates, JM. Primary leiomyosarcoma of extragnathic bone: clinicopathologic features and reevaluation of prognosis. Arch Pathol Lab Med, 133(9), 1448-56, 2009

Cates, JM, Byrd, RH, Fohn, LE, Tatsas, AD, Washington, MK, Black, CC. Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma. Pancreas, 38(1), e1-6, 2009

Herceg, ME, Tsiatis, AC, Halpern, JL, Holt, GE, Schwartz, HS, Keedy, VL, Cates, JM. Cyclooxygenase 2 expression in soft tissue leiomyosarcoma. Anticancer Res, 29(8), 2913-7, 2009

Li, B, Vincent, A, Cates, J, Brantley-Sieders, DM, Polk, DB, Young, PP. Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site. Cancer Res, 69(1), 338-48, 2009 PMCID:2651676

Tsiatis, AC, Herceg, ME, Keedy, VL, Halpern, JL, Holt, GE, Schwartz, HS, Cates, JM. Prognostic significance of c-Myc expression in soft tissue leiomyosarcoma. Mod Pathol, 22(11), 1432-8, 2009 PMCID:2751643

Alfaro, MP, Pagni, M, Vincent, A, Atkinson, J, Hill, MF, Cates, J, Davidson, JM, Rottman, J, Lee, E, Young, PP. The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. Proc Natl Acad Sci U S A, 105(47), 18366-71, 2008 PMCID:2587631

Brantley-Sieders, DM, Zhuang, G, Hicks, D, Fang, WB, Hwang, Y, Cates, JM, Coffman, K, Jackson, D, Bruckheimer, E, Muraoka-Cook, RS, Chen, J. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J Clin Invest, 118(1), 64-78, 2008 PMCID:2129239

Cates, JM, Dupont, WD, Barnes, JW, Edmunds, HS, Fasig, JH, Olson, SJ, Black, CC. Markers of epithelial-mesenchymal transition and epithelial differentiation in sarcomatoid carcinoma: utility in the differential diagnosis with sarcoma. Appl Immunohistochem Mol Morphol, 16(3), 251-62, 2008

Fasig, JH, Dupont, WD, LaFleur, BJ, Olson, SJ, Cates, JM. Immunohistochemical analysis of receptor tyrosine kinase signal transduction activity in chordoma. Neuropathol Appl Neurobiol, 34(1), 95-104, 2008

Hoene, KA, Kaufman, MR, Cates, JM, Chang, SS. Inflammatory myofibroblastic tumor of the urinary bladder in a 27-year-old woman with systemic lupus erythematosus. Int J Urol, 15(2), 182-4, 2008

Noordzij, JP, Cates, JM, Cohen, SM, Bennett, ML, Ries, WM, Russell, PT, Haynes, D, Garrett, CG, Ossoff, RH. Preparation techniques for the injection of human autologous cartilage: an ex vivo feasibility study. Laryngoscope, 118(1), 185-8, 2008

Tsiatis, AC, Atkinson, JB, Wright, JK, Cates, JM. Primary hepatic myxoid leiomyosarcoma: a case report and review of the literature. Ultrastruct Pathol, 32(1), 25-8, 2008

Fasig, JH, Dupont, WD, Olson, SJ, Lafleur, BJ, Cates, JM. Steroid hormone receptor and COX-2 expression in chordoma. Am J Clin Pathol, 128(3), 375-81, 2007

Cates, JM, Coffing, BN, Harris, BT, Black, CC. Calretinin expression in tumors of adipose tissue. Hum Pathol, 37(3), 312-21, 2006

Pitchford, CW, Schwartz, HS, Atkinson, JB, Cates, JM. Soft tissue perineurioma in a patient with neurofibromatosis type 2: a tumor not previously associated with the NF2 syndrome. Am J Surg Pathol, 30(12), 1624-9, 2006

Cates, JM, Williams, TL, Suriawinata, AA. Intraductal papillary mucinous adenoma that arises from pancreatic heterotopia within a meckel diverticulum. Arch Pathol Lab Med, 129(3), e67-9, 2005

Gutmann, EJ, Cates, JM. Initial diagnosis of breast cancer via cytological examination of a pleural effusion: a rare event facilitated by recognition of an unusual morphological pattern. Diagn Cytopathol, 32(3), 177-81, 2005

Lin, JT, Kitzmiller, TJ, Cates, JM, Gorham, JD. MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury. Lab Invest, 85(4), 550-61, 2005

Pipas, JM, Barth, RJ, Zaki, B, Tsapakos, MJ, Suriawinata, AA, Bettmann, MA, Cates, JM, Ripple, GH, Sutton, JE, Gordon, SR, McDonnell, CE, Perez, RP, Redfield, N, Meyer, LP, Marshall, JF, Cole, BF, Colacchio, TA. Docetaxel/Gemcitabine followed by gemcitabine and external beam radiotherapy in patients with pancreatic adenocarcinoma. Ann Surg Oncol, 12(12), 995-1004, 2005

Gardner, TB, Manning, HL, Beelen, AP, Cimis, RJ, Cates, JM, Lewis, LD. Ethylene glycol toxicity associated with ischemia, perforation, and colonic oxalate crystal deposition. J Clin Gastroenterol, 38(5), 435-9, 2004

Rudner, LA, Lin, JT, Park, IK, Cates, JM, Dyer, DA, Franz, DM, French, MA, Duncan, EM, White, HD, Gorham, JD. Necroinflammatory liver disease in BALB/c background, TGF-beta 1-deficient mice requires CD4+ T cells. J Immunol, 170(9), 4785-92, 2003

Hau, MA, Fox, EJ, Cates, JM, Brigman, BE, Mankin, HJ. Jaffe-Campanacci syndrome. A case report and review of the literature. J Bone Joint Surg Am, 84-A(4), 634-8, 2002

Ramnath, RR, Rosenthal, DI, Cates, J, Gebhardt, M, Quinn, RH. Intracortical chondroma simulating osteoid osteoma treated by radiofrequency. Skeletal Radiol, 31(10), 597-602, 2002

Sami, S, Liu, G, Hornicek, F, Cates, JM, Mankin, HJ. Membranous lipodystrophy. A case report. J Bone Joint Surg Am, 84-A(4), 630-3, 2002

Tang, P, Hornicek, FJ, Gebhardt, MC, Cates, J, Mankin, HJ. Surgical treatment of hemangiomas of soft tissue. Clin Orthop Relat Res(399), 205-10, 2002

Cates, JM, Rosenberg, AE, O''Connell, JX, Nielsen, GP. Chondroblastoma-like chondroma of soft tissue: an underrecognized variant and its differential diagnosis. Am J Surg Pathol, 25(5), 661-6, 2001

Erickson, JK, Rosenthal, DI, Zaleske, DJ, Gebhardt, MC, Cates, JM. Primary treatment of chondroblastoma with percutaneous radio-frequency heat ablation: report of three cases. Radiology, 221(2), 463-8, 2001

Cates, JM, Damassa, DA. Characterization and developmental expression patterns of testicular androgen-binding protein in the Djungarian hamster (Phodopus sungorus). J Reprod Fertil, 111(2), 291-8, 1997

Cates, JM, Damassa, DA, Gagin, GA, Dempsey, RV. Hepatic expression of sex hormone-binding globulin associated with the postnatal surge of serum androgen-binding activity in the Djungarian hamster. J Steroid Biochem Mol Biol, 55(2), 147-58, 1995

Damassa, DA, Cates, JM. Sex hormone-binding globulin and male sexual development. Neurosci Biobehav Rev, 19(2), 165-75, 1995

Yu, M, Cates, J, Leav, I, Ho, SM. Heterogeneity of [3H]estradiol binding sites in the rat prostate: properties and distribution of type I and type II sites. J Steroid Biochem, 33(3), 449-57, 1989

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