Biomedical Research Education & Training
Faculty Member

Quarles, Christopher Chad, PhD
Assistant Professor of Radiology and Radiological Sciences
Assistant Professor of Physics
Assistant Professor of Physics
Assistant Professor of Biomedical Engineering
Assistant Professor of Cancer Biology

Lab Url: http://vuiis.vanderbilt.edu

Phone Number: (615) 322-6215

Email Address: chad.quarles@vanderbilt.edu

Quarles, Christopher's picture
Academic history
BS, Centenary College of Louisiana
PhD, Medical College of Wisconsin

Office Address   Mailing Address

AAA-3123 Medical Center North/VUIIS (2675)

1161 21st Avenue South MCN AA-1105 37232-2310


Research Keywords
cancer imaging, renal imaging, MRI, PET, SPECT, CT

Research Description
Dr. Quarles's research focuses on the development and validation of multi-modal imaging methods for the non-invasive assessment of cancer and renal pathophysiology. Using MRI, PET and SPECT imaging techniques with and without targeted contrast agents his lab investigates markers of abnormal cancer metabolism, oxygenation status and angiogenesis in pre-clinical models of cancer.

Publications
Dortch, RD, Yankeelov, TE, Yue, Z, Quarles, CC, Gore, JC, Does, MD. Evidence of multiexponential T2 in rat glioblastoma. NMR Biomed, 22(6), 609-18, 2009

Colvin, DC, Yankeelov, TE, Does, MD, Yue, Z, Quarles, C, Gore, JC. New insights into tumor microstructure using temporal diffusion spectroscopy. Cancer Res, 68(14), 5941-7, 2008 PMCID:2719758

Quarles, CC, Lepage, M, Gorden, DL, Fingleton, B, Yankeelov, TE, Price, RR, Matrisian, LM, Gore, JC, McIntyre, JO. Functional colonography of Min mice using dark lumen dynamic contrast-enhanced MRI. Magn Reson Med, 60(3), 718-26, 2008 PMCID:2646120

Lepage, M, Dow, WC, Melchior, M, You, Y, Fingleton, B, Quarles, CC, P??pin, C, Gore, JC, Matrisian, LM, McIntyre, JO. Noninvasive detection of matrix metalloproteinase activity in vivo using a novel magnetic resonance imaging contrast agent with a solubility switch. Mol Imaging, 6(6), 393-403, 2007

Quarles, CC, Schmainda, KM. Assessment of the morphological and functional effects of the anti-angiogenic agent SU11657 on 9L gliosarcoma vasculature using dynamic susceptibility contrast MRI. Magn Reson Med, 57(4), 680-7, 2007

Yankeelov, TE, Niermann, KJ, Huamani, J, Kim, DW, Quarles, CC, Fleischer, AC, Hallahan, DE, Price, RR, Gore, JC. Correlation between estimates of tumor perfusion from microbubble contrast-enhanced sonography and dynamic contrast-enhanced magnetic resonance imaging. J Ultrasound Med, 25(4), 487-97, 2006

Quarles, CC, Krouwer, HG, Rand, SD, Schmainda, KM. Dexamethasone normalizes brain tumor hemodynamics as indicated by dynamic susceptibility contrast MRI perfusion parameters. Technol Cancer Res Treat, 4(3), 245-9, 2005

Quarles, CC, Ward, BD, Schmainda, KM. Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation. Magn Reson Med, 53(6), 1307-16, 2005


Postdoctoral Position Available
N/A

Postdoctoral Position Details
N/A

Updated Date
08/03/2009