Biomedical Research Education & Training
Faculty Member

Hartert, Tina V., M.D., M.P.H.
Director, Center for Asthma and Environmental Sciences Research
Associate Dean for Physician-Researcher Training
Professor of Medicine
Lulu H. Owen Chair in Medicine

Lab Url: N/A

Phone Number: 615-936-1010

Email Address:

Hartert, Tina's picture
Academic history
BA, Brown University
MD, Vanderbilt University School of Medicine
MD, Vanderbilt University School of Medicine
, Johns Hopkins
, Johns Hopkiins

Office Address   Mailing Address

Suite Medical Center East

T-1218 MCN 37232-2650

Clinical Research Keywords
Asthma, Epidemiology, Respiratory Epidemiology, Asthma Epidemiology, Primary disease prevention, clinical trials, pulmonary medicine

Patient Care Specialty
Adult Pulmonary and Critical Care Medicine

Clinical Research Description
The Center for Asthma Research???s scientific focus is to identify and elucidate the role of common, modifiable exposures in asthma development, and design and implement interventions for primary and secondary disease prevention. The current major focus of the Center is on early life infections, the microbiome, antioxidants, and medication effectiveness. Study populations and methods include the utilization of large administrative datasets and electronic health records, as well as prospective cohort studies and clinical trials to answer questions about etiologic agents in asthma inception, mechanisms through which etiologic agents contribute, new methods for analyses, and the efficacy of primary prevention interventions. The ultimate goals of the work of her Center are the discovery of primary and secondary disease prevention strategies for asthma.

Tina Hartert, M.D., M.P.H., is a Professor of Medicine, Director of the Center for Asthma Research, and Assistant Dean for Physician-Researcher Training. Dr. Hartert completed an internal medicine residency and chief residency at Johns Hopkins University School of Medicine, a fellowship in Pulmonary & Critical Care Medicine and a Master???s degree in Public Health at Vanderbilt University School of Medicine. Dr. Hartert leads a highly innovative research program which includes investigators with broad backgrounds and which integrates her epidemiology training with her knowledge of clinical and basic science. Dr. Hartert is an elected member of the American Society of Clinical Investigation (ASCI), an Associate Editor for the American Journal of Respiratory and Critical Care Medicine, and she has been recognized for her teaching and mentoring contributions. In addition, she has served as a member of a number of NIH expert panels establishing disease and research guidelines, as well as delineating future research agendas. Her current research is supported by extramurally funded grants from the NIH and AHRQ. She is especially proud of the accomplishments of her trainees over that past several years. She has mentored 6 K-awardees and multiple grant recipients who have published over 50 first author manuscripts and 60 abstracts. Eleven of her trainees are faculty members at academic institutions.

Clinical Interests
Asthma and general pulmonary diseases

Arnold, DH, Gebretsadik, T, Hartert, TV. Spirometry and PRAM Severity Score Changes During Pediatric Acute Asthma Exacerbation Treatment in a Pediatric Emergency Department. J Asthma, 50(2), 204-8, 2013

Carroll, KN, Hartert, TV. Reply. J Allergy Clin Immunol, 131(2), 616-7, 2013

James, KM, Gebretsadik, T, Escobar, GJ, Wu, P, Carroll, KN, Li, SX, Walsh, EM, Mitchel, EF, Sloan, C, Hartert, TV. Risk of childhood asthma following infant bronchiolitis during the respiratory syncytial virus season. J Allergy Clin Immunol, 2013

Arnold, DH, Gebretsadik, T, Abramo, TJ, Hartert, TV. Noninvasive testing of lung function and inflammation in pediatric patients with acute asthma exacerbations. J Asthma, 49(1), 29-35, 2012

Arnold, DH, Gebretsadik, T, Abramo, TJ, Sheller, JR, Resha, DJ, Hartert, TV. The Acute Asthma Severity Assessment Protocol (AASAP) study: objectives and methods of a study to develop an acute asthma clinical prediction rule. Emerg Med J, 29(6), 444-50, 2012

Carroll, KN, Gebretsadik, T, Minton, P, Woodward, K, Liu, Z, Miller, EK, Williams, JV, Dupont, WD, Hartert, TV. Influence of maternal asthma on the cause and severity of infant acute respiratory tract infections. J Allergy Clin Immunol, 129(5), 1236-42, 2012

Carroll, KN, Griffin, MR, Edwards, KM, Ali, A, Zhu, Y, Iwane, MK, Szilagyi, PG, Staat, MA, Stevens, TP, Hall, CB, Williams, JV, Hartert, TV. Adherence to guidelines for respiratory syncytial virus immunoprophylaxis among infants with prematurity or chronic lung disease in three United States counties. Pediatr Infect Dis J, 31(11), e229-31, 2012

Hayes, RM, Wu, P, Shelton, RC, Cooper, WO, Dupont, WD, Mitchel, E, Hartert, TV. Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies. Am J Obstet Gynecol, 207(1), 49.e1-9, 2012

James, KM, Peebles, RS, Hartert, TV. Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility. J Allergy Clin Immunol, 130(2), 343-51, 2012

Klemenc, J, Asad Ali, S, Johnson, M, Tollefson, SJ, Talbot, HK, Hartert, TV, Edwards, KM, Williams, JV. Real-time reverse transcriptase PCR assay for improved detection of human metapneumovirus. J Clin Virol, 54(4), 371-5, 2012

Ali, SA, Gern, JE, Hartert, TV, Edwards, KM, Griffin, MR, Miller, EK, Gebretsadik, T, Pappas, T, Lee, WM, Williams, JV. Real-world comparison of two molecular methods for detection of respiratory viruses. Virol J, 8, 332, 2011

Arnold, DH, Gebretsadik, T, Abramo, TJ, Moons, KG, Sheller, JR, Hartert, TV. The RAD score: a simple acute asthma severity score compares favorably to more complex scores. Ann Allergy Asthma Immunol, 107(1), 22-8, 2011

Carroll, KN, Gebretsadik, T, Larkin, EK, Dupont, WD, Liu, Z, Van Driest, S, Hartert, TV. Relationship of maternal vitamin D level with maternal and infant respiratory disease. Am J Obstet Gynecol, 205(3), 215.e1-7, 2011

Larkin, EK, Gebretsadik, T, Koestner, N, Newman, MS, Liu, Z, Carroll, KN, Minton, P, Woodward, K, Hartert, TV. Agreement of blood spot card measurements of vitamin D levels with serum, whole blood specimen types and a dietary recall instrument. PLoS One, 6(1), e16602, 2011

Miller, EK, Williams, JV, Gebretsadik, T, Carroll, KN, Dupont, WD, Mohamed, YA, Morin, LL, Heil, L, Minton, PA, Woodward, K, Liu, Z, Hartert, TV. Host and viral factors associated with severity of human rhinovirus-associated infant respiratory tract illness. J Allergy Clin Immunol, 127(4), 883-91, 2011

Valet, RS, Gebretsadik, T, Carroll, KN, Wu, P, Dupont, WD, Mitchel, EF, Hartert, TV. High asthma prevalence and increased morbidity among rural children in a Medicaid cohort. Ann Allergy Asthma Immunol, 106(6), 467-73, 2011

Wu, P, Hartert, TV. Evidence for a causal relationship between respiratory syncytial virus infection and asthma. Expert Rev Anti Infect Ther, 9(9), 731-45, 2011

Arnold, DH, Jenkins, CA, Hartert, TV. Noninvasive assessment of asthma severity using pulse oximeter plethysmograph estimate of pulsus paradoxus physiology. BMC Pulm Med, 10, 17, 2010

Deng, X, Gebretsadik, T, Jin, M, Gao, YT, Bai, C, Christman, JW, Wen, W, Dupont, WD, Plummer, D, Stephens, J, Shu, XO, Hartert, TV. Development of a nomogram for identification of asthma among adults in epidemiologic studies. Ann Allergy Asthma Immunol, 105(3), 203-10, 2010

Hartert, TV, Carroll, K, Gebretsadik, T, Woodward, K, Minton, P, , . The Tennessee Children''s Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases. Respirology, 15(4), 691-9, 2010

Hartert, Tina V. Acute asthma care interventions in improving asthma outcomes: putting guidelines into action. Ann Allergy Asthma Immunol, 90(1), 8-9, 2003

Hartert, Tina V, Neuzil, Kathleen M, Shintani, Ayumi K, Mitchel, Edward F, Snowden, Mary S, Wood, Lesa B, Dittus, Robert S, Griffin, Marie R. Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza season. Am J Obstet Gynecol, 189(6), 1705-12, 2003

Hartert, Tina V, Speroff, Theodore, Togias, Alkis, Mitchel, Edward F, Snowden, Mary S, Dittus, Robert S, Griffin, Marie R. Risk factors for recurrent asthma hospital visits and death among a population of indigent older adults with asthma. Ann Allergy Asthma Immunol, 89(5), 467-73, 2002

Hashimoto, K, Peebles, R S, Sheller, J R, Jarzecka, K, Furlong, J, Mitchell, D B, Hartert, T V, Graham, B S. Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor. Thorax, 57(6), 524-7, 2002 PMCID:1746359

Lefebvre, Jean, Murphey, Laine J, Hartert, Tina V, Jiao Shan, Ru, Simmons, William H, Brown, Nancy J. Dipeptidyl peptidase IV activity in patients with ACE-inhibitor-associated angioedema. Hypertension, 39(2 Pt 2), 460-4, 2002

Peebles, R Stokes, Hartert, Tina V. Highlights from the annual scientific assembly: patient-centered approaches to asthma management: strategies for treatment and management of asthma. South Med J, 95(7), 775-9, 2002

Dworski, R, Roberts, L J, Murray, J J, Morrow, J D, Hartert, T V, Sheller, J R. Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha). Clin Exp Allergy, 31(3), 387-90, 2001

Hartert, T V, Peebles, R S. Dietary antioxidants and adult asthma. Curr Opin Allergy Clin Immunol, 1(5), 421-9, 2001

Hartert, T V, Dworski, R T, Mellen, B G, Oates, J A, Murray, J J, Sheller, J R. Prostaglandin E(2) decreases allergen-stimulated release of prostaglandin D(2) in airways of subjects with asthma. Am J Respir Crit Care Med, 162(2 Pt 1), 637-40, 2000

Hartert, T V, Peebles, R S. Epidemiology of asthma: the year in review. Curr Opin Pulm Med, 6(1), 4-9, 2000

Hartert, T V, Togias, A, Mellen, B G, Mitchel, E F, Snowden, M S, Griffin, M R. Underutilization of controller and rescue medications among older adults with asthma requiring hospital care. J Am Geriatr Soc, 48(6), 651-7, 2000

Peebles, R S, Hartert, T V. Respiratory viruses and asthma. Curr Opin Pulm Med, 6(1), 10-4, 2000

Hartert, T V, Wheeler, A P, Sheller, J R. Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus. Chest, 115(2), 475-81, 1999

Peebles, R S, Hartert, T V, Sheller, J R. Viral infections in asthma. Compr Ther, 24(10), 511-8, 1998

Peebles, R S, Hartert, T V. In vivo diagnostic procedures: skin testing, nasal provocation, and bronchial provocation. Methods, 13(1), 14-24, 1997

Hartert, T V, Windom, H H, Peebles, R S, Freidhoff, L R, Togias, A. Inadequate outpatient medical therapy for patients with asthma admitted to two urban hospitals. Am J Med, 100(4), 386-94, 1996

Heldman, A W, Hartert, T V, Ray, S C, Daoud, E G, Kowalski, T E, Pompili, V J, Sisson, S D, Tidmore, W C, vom Eigen, K A, Goodman, S N, Lietman, P S, Petty, B G, Flexner, C. Oral antibiotic treatment of right-sided staphylococcal endocarditis in injection drug users: prospective randomized comparison with parenteral therapy. Am J Med, 101(1), 68-76, 1996

Postdoctoral Position Available

Postdoctoral Position Details
POSTDOCTORAL POSITION IN ASTHMA EPIDEMIOLOGY & TRANSLATIONAL RESEARCH. Available position for a recent Ph.D. in epidemiology or clinical-translational research. The major scientific programs of the Center for Asthma Research are to identify common and modifiable etiologies of asthma, and to develop new interventions to prevent the most common acute and chronic diseases of childhood The candidate???s major commitment will be to research with either distinguished performance, or the promise of distinguished performance and independent extramural funded research. Considerable experience in study design, the conduct of epidemiologic, clinical or translational studies, excellent communication skills, ability to work in a team, and strong quantitative skills are essential. If interested, please send a letter of introduction and interest, a curriculum vitae and names and telephone numbers of three references to: Tina Hartert, M.D., M.P.H., c/o Teresa Chipps, Program Coordinator, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Center for Health Services Research, 6107 MCE, Vanderbilt University School of Medicine, Nashville, TN 37232-8300. Fax: 615-936-1269.

Updated Date