Biomedical Research Education & Training
Faculty Member

Gould, Kathleen L., Ph.D.
Professor of Cell and Developmental Biology
Louise B. McGavock Chair

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Phone Number: 615-343-9502

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Gould, Kathleen's picture
Academic history
B.A., Univeristy of California, Berkeley
Ph.D., University of California, San Diego
Postdoctoral Studies, University of Oxford

Office Address   Mailing Address

B-2309 Medical Center North

B-2309 MCN 37232-8240

Research Keywords
cell cycle control, cytokinesis, proteomics, signal transduction, checkpoint signaling, ubiquitination, protein phosphorylation

Research Description
Proper coordination of nuclear and cell division is necessary for the normal development of all eukaryotic organisms and for the maintenance of genomic integrity. The goals of my laboratory are two-fold: 1) to understand the molecular mechanisms regulating cytokinesis and 2) to learn how cytokinesis is coordinated with other events of the cell cycle including chromosome segregation and microtubule cytoskeletal rearrangements. We are asking a) what is the full complement of proteins that comprise the cytokinetic machinery, b) how is the cytokinetic machinery precisely localized between segregating chromosomes, c) what molecular event(s) triggers constriction of the cytokinetic machinery, and d) what ensures the correct timing of cytokinesis with respect to chromosome segregation?
To address these questions expeditiously, we are using yeast as a model organism.
Yeast offers many experimental advantages for the study of cell cycle regulation including facile genetics and a fully sequenced and annotated genome. Using genetics, proteomics, live cell imaging, biochemistry, and structural biology we are unraveling the sequence of events that directs formation and then constriction of the cytokinetic ring. We are also studying protein phosphorylation signaling pathways and ubiquitin ligases that control the spatial precision of cytokinesis, the organization of the microtubule cytoskeleton through the cell cycle, and the timing of cytokinetic events during mitosis.

Bajpai, A, Feoktistova, A, Chen, JS, McCollum, D, Sato, M, Carazo-Salas, RE, Gould, KL, Csik??sz-Nagy, A. Dynamics of SIN Asymmetry Establishment. PLoS Comput Biol, 9(7), e1003147, 2013

Chen, JS, Broadus, MR, McLean, JR, Feoktistova, A, Ren, L, Gould, KL. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast Clp1/Cdc14 phosphatase. Mol Cell Proteomics, 2013

Dephoure, N, Gould, KL, Gygi, SP, Kellogg, DR. Mapping and analysis of phosphorylation sites: a quick guide for cell biologists. Mol Biol Cell, 24(5), 535-42, 2013

Gupta, S, Mana-Capelli, S, McLean, JR, Chen, CT, Ray, S, Gould, KL, McCollum, D. Identification of SIN pathway targets reveals mechanisms of crosstalk between NDR kinase pathways. Curr Biol, 23(4), 333-8, 2013

Bohnert, KA, Gould, KL. Cytokinesis-based constraints on polarized cell growth in fission yeast. PLoS Genet, 8(10), e1003004, 2012

Broadus, MR, Gould, KL. Multiple protein kinases influence the redistribution of fission yeast Clp1/Cdc14 phosphatase upon genotoxic stress. Mol Biol Cell, 23(20), 4118-28, 2012

Clement, A, Solnica-Krezel, L, Gould, KL. Functional redundancy between Cdc14 phosphatases in zebrafish ciliogenesis. Dev Dyn, 2012

Feoktistova, A, Morrell-Falvey, J, Chen, JS, Singh, NS, Balasubramanian, MK, Gould, KL. The fission yeast SIN kinase, Sid2, is required for SIN asymmetry and regulates the SIN scaffold, Cdc11. Mol Biol Cell, 23(9), 1636-45, 2012

Johnson, AE, Collier, SE, Ohi, MD, Gould, KL. Fission yeast Dma1 requires RING domain dimerization for its ubiquitin ligase activity and mitotic checkpoint function. J Biol Chem, 287(31), 25741-8, 2012

Johnson, AE, McCollum, D, Gould, KL. Polar opposites: Fine-tuning cytokinesis through SIN asymmetry. Cytoskeleton (Hoboken), 69(10), 686-99, 2012

Lu, LX, Domingo-Sananes, MR, Huzarska, M, Novak, B, Gould, KL. Multisite phosphoregulation of Cdc25 activity refines the mitotic entrance and exit switches. Proc Natl Acad Sci U S A, 109(25), 9899-904, 2012

Ma H, McLean JR, Chao LF, Mana-Capelli S, Paramasivam M, Hagstrom KA, Gould KL, McCollum D.. A highly efficient multifunctional tandem affinity purification approachapplicable to diverse organisms. Mol Cell Proteomics, 11(8), 501-11, 2012

Mana-Capelli, S, McLean, JR, Chen, CT, Gould, KL, McCollum, D. The kinesin-14 Klp2 is negatively regulated by the SIN for proper spindle elongation and telophase nuclear positioning. Mol Biol Cell, 23(23), 4592-600, 2012

Pancaldi V, Sara?? OS, Rallis C, McLean JR, P??evorovsk?? M, Gould K, Beyer A, B??hler J.. Predicting the fission yeast protein interaction network. G3: Genes, Genomes and Genetics, 2(4), 453-67, 2012

Wang, Y, Li, WZ, Johnson, AE, Luo, ZQ, Sun, L, Feoktistova, A, McDonald, WH, McLeod, I, Yates, III, JR, Gould, KL, McCollum, D, and Jin, QW . Dnt1 Acts as a Mitotic Inhibitor of the Spindle Checkpoint Protein Dma1 in Fission Yeast . Mol Biol Cell, 23(17), 3338-56, 2012

Wang, Y, Li, WZ, Johnson, AE, Luo, ZQ, Sun, XL, Feoktistova, A, McDonald, WH, McLeod, I, Yates, JR, Gould, KL, McCollum, D, Jin, QW. Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast. Mol Biol Cell, 23(17), 3348-56, 2012

Almonacid M, Celton-Morizur S, Jakubowski JL, Dingli F, Loew D, Mayeux A, Chen JS, Gould KL, Clifford DM, Paoletti A.. Temporal control of contractile ring assembly by Plo1 regulation of myosin II recruitment by Mid1/anillin.. Cur Biol, 21(6), 473-9, 2011

Bohnert, KA, Gould, KL. On the cutting edge: post-translational modifications in cytokinesis. Trends Cell Biol, 21(5), 283-92, 2011

Chen, JS, Lu, LX, Ohi, MD, Creamer, KM, English, C, Partridge, JF, Ohi, R, Gould, KL. Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation. J Cell Biol, 195(4), 583-93, 2011

Cl??ment, A, Solnica-Krezel, L, Gould, KL. The Cdc14B phosphatase contributes to ciliogenesis in zebrafish. Development, 138(2), 291-302, 2011 PMCID:3005604

Johnson, AE, Gould, KL. Dma1 ubiquitinates the SIN scaffold, Sid4, to impede the mitotic localization of Plo1 kinase. EMBO J, 30(2), 341-54, 2011 PMCID:3005604

McLean, JR, Chaix, D, Ohi, MD, Gould, KL. State of the APC/C: organization, function, and structure. Crit Rev Biochem Mol Biol, 46(2), 118-36, 2011

McLean, JR, Kouranti, I, Gould, KL. Survey of the phosphorylation status of the Schizosaccharomyces pombe deubiquitinating enzyme (DUB) family. J Proteome Res, 10(3), 1208-15, 2011 PMCID:3049645

Peckys, DB, Mazur, P, Gould, KL, de Jonge, N. Fully hydrated yeast cells imaged with electron microscopy. Biophys J, 100(10), 2522-9, 2011

Ren, L, McLean, JR, Hazbun, TR, Fields, S, Vander Kooi, C, Ohi, MD, Gould, KL. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS One, 6(2), e16719, 2011 PMCID:3046128

Singh NS, Shao N, McLean JR, Sevugan M, Ren L, Chew TG, Bimbo A, Sharma R, Tang X, Gould KL, Balasubramanian MK. . SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Curr Biol, 21(23), 1968-78, 2011

Kouranti, I, McLean, JR, Feoktistova, A, Liang, P, Johnson, AE, Roberts-Galbraith, RH, Gould, KL. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. PLoS Biol, 8(9), 2010 PMCID:2935449

Roberts-Galbraith, RH, Gould, KL. Setting the F-BAR: functions and regulation of the F-BAR protein family. Cell Cycle, 9(20), 4091-7, 2010 PMCID:3005604

Roberts-Galbraith, RH, Ohi, MD, Ballif, BA, Chen, JS, McLeod, I, McDonald, WH, Gygi, SP, Yates, JR, Gould, KL. Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Mol Cell, 39(1), 86-99, 2010

Vander Kooi, CW, Ren, L, Xu, P, Ohi, MD, Gould, KL, Chazin, WJ. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. Structure, 18(5), 584-93, 2010

Bohnert, KA, Chen, JS, Clifford, DM, Vander Kooi, CW, Gould, KL. A Link between Aurora Kinase and Clp1/Cdc14 Regulation Uncovered by the Identification of a Fission Yeast Borealin-like Protein. Mol Biol Cell, 2009

Roberts-Galbraith RH, Chen JS, Wang J, Gould KL.. The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring. J Cell Biol, 184(1), 113-27, 2009

Chen CT, Feoktistova A, Chen JS, Shim YS, Clifford DM, Gould KL, McCollum D.. The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1.. Curr Biol, 18(20), 1594-9, 2008

Clifford, DM, Chen, CT, Roberts, RH, Feoktistova, A, Wolfe, BA, Chen, JS, McCollum, D, Gould, KL. The role of Cdc14 phosphatases in the control of cell division. Biochem Soc Trans, 36(Pt 3), 436-8, 2008

Clifford, DM, Wolfe, BA, Roberts-Galbraith, RH, McDonald, WH, Yates, JR, Gould, KL. The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1. J Cell Biol, 181(1), 79-88, 2008 PMCID:2287289

Roberts-Galbraith, RH, Gould, KL. Stepping into the ring: the SIN takes on contractile ring assembly. Genes Dev, 22(22), 3082-8, 2008

Sczaniecka M, Feoktistova A, May KM, Chen JS, Blyth J, Gould KL, Hardwick KG.. The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).. J Biol Chem, 283(34), 23039-47, 2008

Ohi, M.D., Feoktistova, A. Ren, L., Yip, C., Cheng, Y., Chen, J.-S., Yoon, H.-J., Wall, J.S., Huang, Z., Penczek, P.A., Gould, K.L.*, and Walz, T.* . Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.. Mol Cell, 28, 871-885, 2007, *co-corresponding authors

Ohi, MD, Ren, L, Wall, JS, Gould, KL, Walz, T. Structural characterization of the fission yeast U5.U2/U6 spliceosome complex. Proc Natl Acad Sci U S A, 104(9), 3195-200, 2007 PMCID:1805518

Mehta, S, Gould, KL. Identification of functional domains within the SIN kinase Cdc7. J Biol Chem, 281(15), 9935-41, 2006

Rosenberg, JA, Tomlin, GC, McDonald, WH, Snydsman, BE, Muller, EG, Yates, JR, Gould, KL. Ppc89 links multiple proteins, including the septation initiation network, to the core of the fission yeast spindle-pole body. Mol Biol Cell, 17(9), 3793-805, 2006 PMCID:1593159

Vander Kooi, CW, Ohi, MD, Rosenberg, JA, Oldham, ML, Newcomer, ME, Gould, KL, Chazin, WJ. The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases(,). Biochemistry, 45(1), 121-130, 2006 PMCID:2570371

Wolfe, BA, McDonald, WH, Yates, JR, Gould, KL. Phospho-Regulation of the Cdc14/Clp1 Phosphatase Delays Late Mitotic Events in S. pombe. Dev Cell, 11(3), 423-30, 2006

Yoon, HJ, Feoktistova, A, Chen, JS, Jennings, JL, Link, AJ, Gould, KL. Role of HCN1 and its phosphorylation in fission yeast APC/C function. J Biol Chem, 28(43), 32284-93, 2006

Alonso-Nu??ez, ML, An, H, Mart?-n-Cuadrado, AB, Mehta, S, Petit, C, Sipiczki, M, Del Rey, F, Gould, KL, V?!zquez de Aldana, CR. Ace2p Controls the Expression of Genes Required for Cell Separation in Schizosaccharomyces pombe. Mol Biol Cell, 16, 2003-17, 2005 PMCID:1073678

Carnahan, RH, Feoktistova, A, Ren, L, Niessen, S, Yates, JR, Gould, KL. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Eukaryot Cell, 4(3), 577-87, 2005 PMCID:1087801

Mart?-n-Cuadrado, AB, Morrell, JL, Konomi, M, An, H, Petit, C, Osumi, M, Balasubramanian, M, Gould, KL, Del Rey, F, de Aldana, CR. Role of septins and the exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation. Mol Biol Cell, 16(10), 4867-81, 2005 PMCID:1237089

Morrell-Falvey, JL, Ren, L, Feoktistova, A, Haese, GD, Gould, KL. Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p. J Cell Sci, 118(Pt 23), 5563-73, 2005

Ohi, MD, Vander Kooi, CW, Rosenberg, JA, Ren, L, Hirsch, JP, Chazin, WJ, Walz, T, Gould, KL. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol, 25(1), 451-60, 2005 PMCID:538785

Petit, CS, Mehta, S, Roberts, RH, Gould, KL. Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. J Cell Sci, 118(Pt 24), 5731-42, 2005

Venkatram, S, Jennings, JL, Link, A, Gould, KL. Mto2p, a novel fission yeast protein required for cytoplasmic microtubule organization and anchoring of the cytokinetic actin ring. Mol Biol Cell, 16(6), 3052-63, 2005 PMCID:1142447

Wolfe, BA, Gould, KL. Split decisions: coordinating cytokinesis in yeast. Trends Cell Biol, 15(1), 10-18, 2005

An, Hanbing, Morrell, Jennifer L, Jennings, Jennifer L, Link, Andrew J, Gould, Kathleen L. Requirements of fission yeast septins for complex formation, localization, and function. Mol Biol Cell, 15(12), 5551-64, 2004 PMCID:532033

Gould, Kathleen L, Ren, Liping, Feoktistova, Anna S, Jennings, Jennifer L, Link, Andrew J. Tandem affinity purification and identification of protein complex components. Methods, 33(3), 239-44, 2004

Morrell, JL, Tomlin, GC, Rajagopalan, S, Venkatram, S, Feoktistova, AS, Tasto, JJ, Mehta, S, Jennings, JL, Link, A, Balasubramanian, MK, Gould, KL. Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB. Curr Biol, 14(7), 579-84, 2004

Morrell, Jennifer L, Nichols, Connie B, Gould, Kathleen L. The GIN4 family kinase, Cdr2p, acts independently of septins in fission yeast. J Cell Sci, 117(Pt 22), 5293-302, 2004

Venkatram, Srinivas, Tasto, Joseph J., Feoktistova, Anna, Jennings, Jennifer L., Link, Andrew J., Gould, Kathleen L.. Identification and characterization of two novel proteins affecting fission yeast {gamma}-tubulin complex function. Mol Biol Cell, 15(5), 2287-301, 2004 PMCID:404023

Wolfe, Benjamin A, Gould, Kathleen L. Inactivating cdc25, mitotic style. Cell Cycle, 3(5), 601-3, 2004

Wolfe, Benjamin A, Gould, Kathleen L. Fission yeast Clp1p phosphatase affects G(2)/M transition and mitotic exit through Cdc25p inactivation. EMBO J, 23(4), 919-29, 2004 PMCID:381010

Carnahan, Robert H, Gould, Kathleen L. The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe. J Cell Biol, 162(5), 851-62, 2003 PMCID:2172828

Ohi, Melanie D, Vander Kooi, Craig W, Rosenberg, Joshua A, Chazin, Walter J, Gould, Kathleen L. Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat Struct Biol, 10, 250-5, 2003

Tasto, Joseph J, Morrell, Jennifer L, Gould, Kathleen L. An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation. J Cell Biol, 160, 1093-103, 2003 PMCID:2172762

Guertin, D.A., Venkatram, S., Gould, K.L., and McCollum, D. .. Dma1 prevents mitotic exit and cytokinesis by inhibiting the Septation Initiation Network (SIN). Dev. Cell, 3(8), 779-790, 2002

Burns, C Geoffrey, Ohi, Ryoma, Mehta, Sapna, O'Toole, Eileen T, Winey, Mark, Clark, Tyson A, Sugnet, Charles W, Ares, Manuel, Gould, Kathleen L. Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Mol Cell Biol, 22(3), 801-15, 2002 PMCID:133559

Guertin, DA, Venkatram, S, Gould, KL, McCollum, D. Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN). Dev Cell, 3(6), 779-90, 2002

MacCoss, MJ, McDonald, WH, Saraf, A, Sadygov, R, Clark, JM, Tasto, JJ, Gould, KL, Wolters, D, Washburn, M, Weiss, A, Clark, JI, Yates, JR. Shotgun identification of protein modifications from protein complexes and lens tissue. Proc Natl Acad Sci U S A, 99(12), 7900-5, 2002 PMCID:122992

Ohi, Melanie D, Gould, Kathleen L. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA, 8(6), 798-815, 2002 PMCID:1370298

Ohi, Melanie D, Link, Andrew J, Ren, Liping, Jennings, Jennifer L, McDonald, W Hayes, Gould, Kathleen L. Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol, 22(7), 2011-24, 2002 PMCID:133674

Tomlin, Gregory C, Morrell, Jennifer L, Gould, Kathleen L. The spindle pole body protein Cdc11p links Sid4p to the fission yeast septation initiation network. Mol Biol Cell, 13, 1203-14, 2002 PMCID:102262

Yoon, Hyun-Joo, Feoktistova, Anna, Wolfe, Benjamin A, Jennings, Jennifer L, Link, Andrew J, Gould, Kathleen L. Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes. Curr Biol, 12(23), 2048-54, 2002

Chang, L, Morrell, J L, Feoktistova, A, Gould, K L. Study of cyclin proteolysis in anaphase-promoting complex (APC) mutant cells reveals the requirement for APC function in the final steps of the fission yeast septation initiation network. Mol Cell Biol, 21(19), 6681-94, 2001 PMCID:99813

Feoktistova, A, Magnelli, P, Abeijon, C, Perez, P, Lester, R L, Dickson, R C, Gould, K L. Coordination between fission yeast glucan formation and growth requires a sphingolipase activity. Genetics, 158(4), 1397-411, 2001 PMCID:1461765

McCollum, D, Gould, KL. Timing is everything: regulation of mitotic exit and cytokinesis by the MEN and SIN. Trends Cell Biol, 11(2), 89-95, 2001

Tasto, J J, Carnahan, R H, McDonald, W H, Gould, K L. Vectors and gene targeting modules for tandem affinity purification in Schizosaccharomyces pombe. Yeast, 18(7), 657-62, 2001

Trautmann, S, Wolfe, BA, Jorgensen, P, Tyers, M, Gould, KL, McCollum, D. Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression. Curr Biol, 11(12), 931-40, 2001

Chang, L, Gould, K L. Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast. Proc Natl Acad Sci U S A, 97(10), 5249-54, 2000 PMCID:25814

Guertin, DA, Chang, L, Irshad, F, Gould, KL, McCollum, D. The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast. EMBO J, 19(8), 1803-15, 2000 PMCID:302011

Berry, L D, Feoktistova, A, Wright, M D, Gould, K L. The schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function. Mol Cell Biol, 19(4), 2535-46, 1999 PMCID:84046

Burns, C G, Gould, K L. Connections between pre-mRNA processing and regulation of the eukaryotic cell cycle. Front Horm Res, 25, 59-82, 1999

Burns, C G, Ohi, R, Krainer, A R, Gould, K L. Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing. Proc Natl Acad Sci U S A, 96(24), 13789-94, 1999 PMCID:24143

Feoktistova, A, McCollum, D, Ohi, R, Gould, K L. Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin. Genetics, 152(3), 895-908, 1999 PMCID:1460656

Machesky, LM, Gould, KL. The Arp2/3 complex: a multifunctional actin organizer. Curr Opin Cell Biol, 11(1), 117-21, 1999

McCollum, D, Feoktistova, A, Gould, K L. Phosphorylation of the myosin-II light chain does not regulate the timing of cytokinesis in fission yeast. J Biol Chem, 274(25), 17691-5, 1999

McDonald, W H, Ohi, R, Smelkova, N, Frendewey, D, Gould, K L. Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. Mol Cell Biol, 19(8), 5352-62, 1999 PMCID:84378

Morrell, J L, Morphew, M, Gould, K L. A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Mol Biol Cell, 10(12), 4201-15, 1999 PMCID:25753

Naqvi, NI, Eng, K, Gould, KL, Balasubramanian, MK. Evidence for F-actin-dependent and -independent mechanisms involved in assembly and stability of the medial actomyosin ring in fission yeast. EMBO J, 18(4), 854-62, 1999 PMCID:1171178

Ohi, R, Gould, K L. Regulating the onset of mitosis. Curr Opin Cell Biol, 11(2), 267-73, 1999

Balasubramanian, M K, McCollum, D, Chang, L, Wong, K C, Naqvi, N I, He, X, Sazer, S, Gould, K L. Isolation and characterization of new fission yeast cytokinesis mutants. Genetics, 149(3), 1265-75, 1998 PMCID:1460233

Breeding, C S, Hudson, J, Balasubramanian, M K, Hemmingsen, S M, Young, P G, Gould, K L. The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe. Mol Biol Cell, 9(12), 3399-415, 1998 PMCID:25645

B??hler, J, Steever, AB, Wheatley, S, Wang, Y, Pringle, JR, Gould, KL, McCollum, D. Role of polo kinase and Mid1p in determining the site of cell division in fission yeast. J Cell Biol, 143(6), 1603-16, 1998 PMCID:2132972

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