Biomedical Research Education & Training
Faculty Member

Nanney, Lillian B., Ph.D.
Professor of Plastic Surgery
Professor of Medical Education and Administration
Professor of Cell and Developmental Biology

Lab Url: N/A

Phone Number: 615-322-7265

Email Address: Lillian.Nanney@vanderbilt.edu

Nanney, Lillian's picture
Academic history
N/AN/AN/A

Office Address   Mailing Address

S-2221 Medical Center North

S-2221 MCN Plastic Surgery Research Laboratory 37232-2631


Research Keywords
wound repair, regeneration, burns, chronic wounds, cutaneous biology, animal models of wound healing, immunohistochemistry, proteomics,Gene therapy,Proteomics,Receptor,Signal transduction,Stem cells

Research Description
The primary goal of the laboratory is to investigate cutaneous growth control mechanisms in the skin whether it be in wound healing settings where accelerated growth or regeneration is desired or whether it be in benign or neoplastic growth where growth inhibition is desired.

Our mechanistic wound healing studies are conducted primarily in porcine and mouse models but typically compared against the molecular events within human skin. We have expanded beyond our original focus of examining the role of ErbB receptors and related cytokines to a more global examination of the complex interplay of genes and proteins expressed in response to cutaneous injury and the subsequent events of wound repair. One goal is to elucidate the temporal sequence of human genes and proteins that are misregulated following injury and which lead to inflammatory perturbations and wound scarring and contracture. The ultimate goal is to discover pivotal molecules that can be either overexpressed or suppressed in the clinical quest to intervene and produce a more timely repair with a more regenerative and aesthetically pleasing outcome.

Dr. Nanney also serves as the Director of Vanderbilt's Instituional Immunohistochemistry Core. She directs a team that is always testing new antisera and developing successful immunostaining working protocols that become immediately available to Vanderbilt's research community. The core also provides routine embedding and histological services for human and animal tissues.

Dr. Nanney is the founding Director of the Academy for Excellence in Teaching that was recently established within the Medical Center.
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Publications
Alfaro, MP, Deskins, DL, Wallus, M, DasGupta, J, Davidson, JM, Nanney, LB, A Guney, M, Gannon, M, Young, PP. A physiological role for connective tissue growth factor in early wound healing. Lab Invest, 93(1), 81-95, 2013

Rodriguez-Feo, CL, Sexton, KW, Boyer, RB, Pollins, AC, Cardwell, NL, Nanney, LB, Shack, RB, Mikesh, MA, McGill, CH, Driscoll, CW, Bittner, GD, Thayer, WP. Blocking the P2X7 receptor improves outcomes after axonal fusion. J Surg Res, 2013

Sexton, KW, Pollins, AC, Cardwell, NL, Del Corral, GA, Bittner, GD, Shack, RB, Nanney, LB, Thayer, WP. Hydrophilic polymers enhance early functional outcomes after nerve autografting. J Surg Res, 177(2), 392-400, 2012

Spear, ME, Nanney, LB, Phillips, S, Donahue, R, Rogers, KM, Wendel, JJ, Summit, B, Kelly, K, Shack, RB, Hagan, KF. The impact of reduction mammaplasty on breast sensation: an analysis of multiple surgical techniques. Ann Plast Surg, 68(2), 142-9, 2012

Adolph, EJ, Hafeman, AE, Davidson, JM, Nanney, LB, Guelcher, SA. Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds. J Biomed Mater Res A, 2011

Hafeman, AE, Zienkiewicz, KJ, Zachman, AL, Sung, HJ, Nanney, LB, Davidson, JM, Guelcher, SA. Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds. Biomaterials, 32(2), 419-29, 2011

Greco, JA, Pollins, AC, Boone, BE, Levy, SE, Nanney, LB. A microarray analysis of temporal gene expression profiles in thermally injured human skin. Burns, 36(2), 192-204, 2010

Russell, SB, Russell, JD, Trupin, KM, Gayden, AE, Opalenik, SR, Nanney, LB, Broquist, AH, Raju, L, Williams, SM. Epigenetically Altered Wound Healing in Keloid Fibroblasts. J Invest Dermatol, 2010

Fogerty, M, Guy, J, Barbul, A, Nanney, LB, Abumrad, NN. African Americans show increased risk for pressure ulcers: A retrospective analysis of acute care hospitals in America. Wound Repair Regen, 17(5), 678-84, 2009

Nading, MA, Nanney, LB, Ellis, DL. Pregnancy and estrogen receptor beta expression in a large congenital nevus. Arch Dermatol, 145(6), 691-4, 2009

Caldwell, RL, Opalenik, SR, Davidson, JM, Caprioli, RM, Nanney, LB. Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds. Wound Repair Regen, 16(3), 442-9, 2008

Chaurand, P, Latham, JC, Lane, KB, Mobley, JA, Polosukhin, VV, Wirth, PS, Nanney, LB, Caprioli, RM. Imaging Mass Spectrometry of Intact Proteins from Alcohol-Preserved Tissue Specimens: Bypassing Formalin Fixation. J Proteome Res, 2008

Fogerty, MD, Abumrad, NN, Nanney, L, Arbogast, PG, Poulose, B, Barbul, A. Risk factors for pressure ulcers in acute care hospitals. Wound Repair Regen, 16(1), 11-8, 2008

Greco, JA, Castaldo, ET, Nanney, LB, Wendel, JJ, Summitt, JB, Kelly, KJ, Braun, SA, Hagan, KF, Shack, RB. The effect of weight loss surgery and body mass index on wound complications after abdominal contouring operations. Ann Plast Surg, 61(3), 235-42, 2008

Greco, JA, Castaldo, ET, Nanney, LB, Wu, YC, Donahue, R, Wendel, JJ, Hagan, KF, Shack, RB. Autologous breast reconstruction: the Vanderbilt experience (1998 to 2005) of independent predictors of displeasing outcomes. J Am Coll Surg, 207(1), 49-56, 2008

Nading, MA, Nanney, LB, Boyd, AS, Ellis, DL. Estrogen receptor beta expression in nevi during pregnancy. Exp Dermatol, 17(6), 489-97, 2008

Nanney, LB, Woodrell, CD, Greives, MR, Cardwell, NL, Pollins, AC, Bancroft, TA, Chesser, A, Michalak, M, Rahman, M, Siebert, JW, Gold, LI. Calreticulin enhances porcine wound repair by diverse biological effects. Am J Pathol, 173(3), 610-30, 2008 PMCID:2527067

Wilmink, GJ, Opalenik, SR, Beckham, JT, Abraham, AA, Nanney, LB, Mahadevan-Jansen, A, Davidson, JM, Jansen, ED. Molecular Imaging-Assisted Optimization of Hsp70 Expression during Laser-Induced Thermal Preconditioning for Wound Repair Enhancement. J Invest Dermatol, 2008

Wilmink, GJ, Opalenik, SR, Beckham, JT, Mackanos, MA, Nanney, LB, Contag, CH, Davidson, JM, Jansen, ED. In-vivo optical imaging of hsp70 expression to assess collateral tissue damage associated with infrared laser ablation of skin. J Biomed Opt, 13(5), 054066, 2008

Caldwell, RL, Opalenik, SR, Davidson, JM, Caprioli, RM, Nanney, LB. Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds. Wound Repair Regen, 2007

Kantrow, SM, Boyd, AS, Ellis, DL, Nanney, LB, Richmond, A, Shyr, Y, Robbins, JB. Expression of activated Akt in benign nevi, Spitz nevi and melanomas. J Cutan Pathol, 34(8), 593-6, 2007 PMCID:2665272

Okwueze, MI, Cardwell, NL, Pollins, AC, Nanney, LB. Modulation of porcine wound repair with a transfected ErbB3 gene and relevant EGF-like ligands. J Invest Dermatol, 127(5), 1030-41, 2007

Okwueze, MI, Cardwell, NL, Wolfort, SL, Nanney, LB. Unexpected motor axons in the distal superficial radial and posterior interosseous nerves: a cadaver study. Clin Anat, 20(7), 790-4, 2007

Pollins, AC, Friedman, DB, Nanney, LB. Proteomic investigation of human burn wounds by 2D-difference gel electrophoresis and mass spectrometry. J Surg Res, 142(1), 143-52, 2007 PMCID:2696121

Rauth, TP, Poulose, BK, Davidson, JM, Nanney, LB, Holzman, MD. Mechanical abrasion improves early incorporation of small intestinal submucosa. Am Surg, 73(7), 647-51; discussion 651, 2007

Rauth, TP, Poulose, BK, Nanney, LB, Holzman, MD. A comparative analysis of expanded polytetrafluoroethylene and small intestinal submucosa--implications for patch repair in ventral herniorrhaphy. J Surg Res, 143(1), 43-9, 2007

Meier, K, Nanney, LB. Emerging new drugs for scar reduction. Expert Opin Emerg Drugs, 11(1), 39-47, 2006

Meier, K, Nanney, LB. Emerging new drugs for wound repair. Expert Opin Emerg Drugs, 11(1), 23-37, 2006

Nanney, LB, Caldwell, RL, Pollins, AC, Cardwell, NL, Opalenik, SR, Davidson, JM. Novel approaches for understanding the mechanisms of wound repair. J Invest Dermatol, 126 Suppl, 132-9, 2006

Nanney, LB, Caldwell, RL, Pollins, AC, Cardwell, NL, Opalenik, SR, Davidson, JM. Novel approaches for understanding the mechanisms of wound repair. J Investig Dermatol Symp Proc, 11(1), 132-9, 2006

Okwueze, MI, Spear, ME, Zwyghuizen, AM, Bra??n, SA, Ajmal, N, Nanney, LB, Hagan, KF, Wolfort, SF, Shack, RB. Effect of augmentation mammaplasty on breast sensation. Plast Reconstr Surg, 117(1), 73-83; discussion 84-5, 2006

Schmidt, AN, Nanney, LB, Boyd, AS, King, LE, Ellis, DL. Oestrogen receptor-beta expression in melanocytic lesions. Exp Dermatol, 15(12), 971-80, 2006

Spindler, KP, Murray, MM, Devin, C, Nanney, LB, Davidson, JM. The central ACL defect as a model for failure of intra-articular healing. J Orthop Res, 24(3), 401-406, 2006

Nanney, L. Looking beneath the surface--setting the stage for skin ulceration. J Invest Dermatol, 125(2), vii-viii, 2005

Poulose BK, Scholz S, Moore DE, Schmidt CR, Grogan EL, Lao OB, Nanney L, Davidson J, Holzman MD . Physiologic properties of porcine small intestine submucosa used as a bioprosthesis. J Surg, 123, 262-267, 2005

Poulose, BK, Scholz, S, Moore, DE, Schmidt, CR, Grogan, EL, Lao, OB, Nanney, L, Davidson, J, Holzman, MD. Physiologic properties of small intestine submucosa. J Surg Res, 123(2), 262-7, 2005

Su, Y, Raghuwanshi, SK, Yu, Y, Nanney, LB, Richardson, RM, Richmond, A. Altered CXCR2 signaling in beta-arrestin-2-deficient mouse models. J Immunol, 175(8), 5396-402, 2005 PMCID:2668249

Mikaelian, I, Nanney, LB, Parman, KS, Kusewitt, DF, Ward, JM, N??f, D, Krupke, DM, Eppig, JT, Bult, CJ, Seymour, R, Ichiki, T, Sundberg, JP. Antibodies that label paraffin-embedded mouse tissues: a collaborative endeavor. Toxicol Pathol, 32(2), 181-91, 2004

Organ, EL, Nalbantyan, CD, Nanney, LB, Woodward, SC, Sheng, J, Dubois, RN, Price, J, Sutcliffe, M, Coffey, RJ, Rubin, DH. Effects of transforming growth factor-alpha (TGF-alpha) in vitro and in vivo on reovirus replication. DNA Cell Biol, 23(7), 430-41, 2004

Schneider, C, Strayhorn, WD, Brantley, DM, Nanney, LB, Yull, FE, Brash, AR. Upregulation of 8-lipoxygenase in the dermatitis of IkappaB-alpha-deficient mice. J Invest Dermatol, 122(3), 691-8, 2004

Ajmal, Nadeem, Nanney, Lillian B, Wolfort, Sean F, . Catfish spine envenomation: a case of delayed presentation.. Wilderness Environ Med, 14, 101-5, 2003

Ajmal, Nadeem, Riordan, Colin L, Cardwell, Nancy, Nanney, Lillian B, Shack, R Bruce. The effectiveness of sodium 2-mercaptoethane sulfonate (mesna) in reducing capsular formation around implants in a rabbit model. Plast Reconstr Surg, 112(5), 1455-61; discussion 1462-3, 2003

Ajmal, Nadeem, Riordan, Colin L, Cardwell, Nancy, Nanney, Lillian B, Shack, R Bruce. Chemically assisted capsulectomy in the rabbit model: a new approach. Plast Reconstr Surg, 112(5), 1449-54; discussion 1462-3, 2003

Draper, Bradley K, Komurasaki, Toshi, Davidson, Mari K, Nanney, Lillian B, . Epiregulin is more potent than EGF or TGFalpha in promoting in vitro wound closure due to enhanced ERK/MAPK activation.. J Cell Biochem, 89, 1126-37, 2003

Draper, Bradley K, Komurasaki, Toshi, Davidson, Mari K, Nanney, Lillian B, . Topical epiregulin enhances repair of murine excisional wounds.. Wound Repair Regen, 11, 188-97, 2003

Milatovic, Snjezana, Nanney, Lillian B, Yu, Yingchun, White, John R, Richmond, Ann, . Impaired healing of nitrogen mustard wounds in CXCR2 null mice.. Wound Repair Regen, 11, 213-9, 2003 PMCID:2667443

Riordan, Colin L, McDonough, Mark, Davidson, Jeffrey M, Corley, Randall, Perlov, Cathy, Barton, Ronald, Guy, Jeffrey, Nanney, Lillian B. Noncontact laser Doppler imaging in burn depth analysis of the extremities. J Burn Care Rehabil, 24(4), 177-86, 2003

Spindler, Kurt P, Murray, Martha M, Detwiler, Kenneth B, Tarter, Jeremy T, Dawson, John M, Nanney, Lillian B, Davidson, Jeffrey M, . The biomechanical response to doses of TGF-beta 2 in the healing rabbit medial collateral ligament.. J Orthop Res, 21, 245-9, 2003

Draper, Bradley K, Davidson, Mari K, Nanney, Lillian B, . MMPs and TIMP-1 are differentially expressed between acute murine excisional and laser wounds.. Lasers Surg Med, 30, 106-16, 2002

Du, Jianguo, Luan, Jing, Liu, Hua, Daniel, Thomas O, Peiper, Stephen, Chen, Theresa S, Yu, Yingchun, Horton, Linda W, Nanney, Lillian B, Strieter, Robert M, Richmond, Ann, . Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress.. J Leukoc Biol, 71, 141-53, 2002 PMCID:2665273

Nanney, Lillian B, Bennett, Laura L, . Comparative evaluation of topical antiseptic/antimicrobial treatment on aspects of wound repair in the porcine model.. Ostomy Wound Manage, Suppl, 14-9, 2002

Riordan, Colin L, Nanney, Lillian B, Upton, Joseph, Wolfort, Sean F, . Vascularized medial sural cutaneous nerve based on the superficial sural artery: a reliable nerve graft.. J Reconstr Microsurg, 18, 147-52; discussion 153-4, 2002

Roman, CD, Choy, H, Nanney, L, Riordan, C, Parman, K, Johnson, D, Beauchamp, RD. Vascular endothelial growth factor-mediated angiogenesis inhibition and postoperative wound healing in rats. J Surg Res, 105(1), 43-7, 2002

Spindler, K P, Dawson, J M, Stahlman, G C, Davidson, J M, Nanney, L B, . Collagen expression and biomechanical response to human recombinant transforming growth factor beta (rhTGF-beta2) in the healing rabbit MCL.. J Orthop Res, 20, 318-24, 2002

Weinstein, David D, Spector, Sydney, Nanney, Lillian B, King, Lloyd E, . Endogenous opiate alkaloids and human skin.. J Invest Dermatol, 119, 709-10, 2002

Adcock, D, Paulsen, S, Jabour, K, Davis, S, Nanney, L B, Shack, R B, . Analysis of the effects of deep mechanical massage in the porcine model.. Plast Reconstr Surg, 108, 233-40, 2001

Bennett, L L, Rosenblum, R S, Perlov, C, Davidson, J M, Barton, R M, Nanney, L B, . An in vivo comparison of topical agents on wound repair.. Plast Reconstr Surg, 108, 675-87, 2001

Deane, N G, Parker, M A, Aramandla, R, Diehl, L, Lee, W J, Washington, M K, Nanney, L B, Shyr, Y, Beauchamp, R D, . Hepatocellular carcinoma results from chronic cyclin D1 overexpression in transgenic mice.. Cancer Res, 61, 5389-95, 2001

Nanney, L B, Wamil, B D, Whitsitt, J, Cardwell, N L, Davidson, J M, Yan, H P, Hellerqvist, C G, . CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism.. Angiogenesis, 4, 61-70, 2001

Chen, C L, Yull, F E, Cardwell, N, Singh, N, Strayhorn, W D, Nanney, L B, Kerr, L D, . RAG2-/-, I kappa B-alpha-/- chimeras display a psoriasiform skin disease.. J Invest Dermatol, 115, 1124-33, 2000

Devalaraja, R M, Nanney, L B, Du, J, Qian, Q, Yu, Y, Devalaraja, M N, Richmond, A, . Delayed wound healing in CXCR2 knockout mice.. J Invest Dermatol, 115, 234-44, 2000 PMCID:2664868

Haghnegahdar, H, Du, J, Wang, D, Strieter, R M, Burdick, M D, Nanney, L B, Cardwell, N, Luan, J, Shattuck-Brandt, R, Richmond, A. The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. J Leukoc Biol, 67(1), 53-62, 2000 PMCID:2669312

Nanney, L B, Paulsen, S, Davidson, M K, Cardwell, N L, Whitsitt, J S, Davidson, J M, . Boosting epidermal growth factor receptor expression by gene gun transfection stimulates epidermal growth in vivo.. Wound Repair Regen, 8, 117-27, 2000

Nirodi, C S, Devalaraja, R, Nanney, L B, Arrindell, S, Russell, S, Trupin, J, Richmond, A, . Chemokine and chemokine receptor expression in keloid and normal fibroblasts.. Wound Repair Regen, 8, 371-82, 2000

Brash, A R, Jisaka, M, Boeglin, W E, Chang, M S, Keeney, D S, Nanney, L B, Kasper, S, Matusik, R J, Olson, S J, Shappell, S B, . Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues.. Adv Exp Med Biol, 469, 83-9, 1999

Garrard, CL, Clements, RH, Nanney, L, Davidson, JM, Richards, WO. Adhesion formation is reduced after laparoscopic surgery. Surg Endosc, 13(1), 10-3, 1999

Johnson, E N, Nanney, L B, Virmani, J, Lawson, J A, Funk, C D. Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice. J Invest Dermatol, 112(6), 861-5, 1999

Adcock, D, Paulsen, S, Davis, S, Nanney, L, Shack, RB. Analysis of the cutaneous and systemic effects of Endermologie in the porcine model. Aesthet Surg J, 18(6), 414-20, 1998

Boyd, A S, Nanney, L B, King, L E. Immunoperoxidase evaluation of lichen planus biopsies for hepatitis C virus. Int J Dermatol, 37(4), 260-2, 1998

Keeney, D S, Skinner, C, Travers, J B, Capdevila, J H, Nanney, L B, King, L E, Waterman, M R. Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J Biol Chem, 273(48), 32071-9, 1998

Nanney, L B, Skeel, A, Luan, J, Polis, S, Richmond, A, Wang, M H, Leonard, E J. Proteolytic cleavage and activation of pro-macrophage-stimulating protein and upregulation of its receptor in tissue injury. J Invest Dermatol, 111(4), 573-81, 1998

Paulsen, S M, Nanney, L B, Lynch, J B. Titanium tetrachloride: an unusual agent with the potential to create severe burns. J Burn Care Rehabil, 19(5), 377-81, 1998

Paulsen, S M, Wurster, S H, Nanney, L B. Expression of inducible nitric oxide synthase in human burn wounds. Wound Repair Regen, 6(2), 142-8, 1998

Boyd, A, Nanney, L, Cameron, G, King, L. Expression of bcl-2 in lichen planus, acute graft-versus-host disease, and erythema multiforme. Am J Dermatopathol, 19(1), 46-51, 1997

Charous, S J, Stricklin, G P, Nanney, L B, Netterville, J L, Burkey, B B. Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma. Ann Otol Rhinol Laryngol, 106(4), 271-8, 1997

Jisaka, M, Kim, R B, Boeglin, W E, Nanney, L B, Brash, A R. Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin. J Biol Chem, 272(39), 24410-6, 1997

Nanney, L B, Davidson, M K, Gates, R E, Kano, M, King, L E. Altered distribution and expression of protein tyrosine phosphatases in normal human skin as compared to squamous cell carcinomas. J Cutan Pathol, 24(9), 521-32, 1997

Zhang, T, Nanney, L B, Luongo, C, Lamps, L, Heppner, K J, DuBois, R N, Beauchamp, R D. Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients. Cancer Res, 57(1), 169-75, 1997

Zhang, T, Nanney, L B, Peeler, M O, Williams, C S, Lamps, L, Heppner, K J, DuBois, R N, Beauchamp, R D. Decreased transforming growth factor beta type II receptor expression in intestinal adenomas from Min/+ mice is associated with increased cyclin D1 and cyclin-dependent kinase 4 expression. Cancer Res, 57(9), 1638-43, 1997

Benn, S I, Whitsitt, J S, Broadley, K N, Nanney, L B, Perkins, D, He, L, Patel, M, Morgan, J R, Swain, W F, Davidson, J M. Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin. J Clin Invest, 98(12), 2894-902, 1996 PMCID:507757

Nanney, L B, Sundberg, J P, King, L E. Increased epidermal growth factor receptor in fsn/fsn mice. J Invest Dermatol, 106(6), 1169-74, 1996

Nanney, L B, Wenczak, B A, Lynch, J B. Progressive burn injury documented with vimentin immunostaining. J Burn Care Rehabil, 17(3), 191-8, 1996

Schaffer, C J, Nanney, L B. Cell biology of wound healing. Int Rev Cytol, 169, 151-81, 1996

Spindler, K P, Clark, S W, Nanney, L B, Davidson, J M. Expression of collagen and matrix metalloproteinases in ruptured human anterior cruciate ligament: an in situ hybridization study. J Orthop Res, 14(6), 857-61, 1996

Williams, C S, Luongo, C, Radhika, A, Zhang, T, Lamps, L W, Nanney, L B, Beauchamp, R D, DuBois, R N. Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology, 111(4), 1134-40, 1996

Blessing, M, Nanney, L B, King, L E, Hogan, B L. Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene. Teratog Carcinog Mutagen, 15(1), 11-21, 1995

Morita, K, Hogan, M E, Nanney, L B, King, L E, Manabe, M, Sun, T T, Sundberg, J P. Cutaneous ultrastructural features of the flaky skin (fsn) mouse mutation. J Dermatol, 22(6), 385-95, 1995

Nanney, L B, Mueller, S G, Bueno, R, Peiper, S C, Richmond, A. Distributions of melanoma growth stimulatory activity of growth-regulated gene and the interleukin-8 receptor B in human wound repair. Am J Pathol, 147(5), 1248-60, 1995 PMCID:1869526

Nanney, LB, Fortney, DZ, Durham, DR. Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds. Wound Repair Regen, 3(4), 442-8, 1995

Roesel, J F, Nanney, L B. Assessment of differential cytokine effects on angiogenesis using an in vivo model of cutaneous wound repair. J Surg Res, 58(5), 449-59, 1995

Spindler, KP, Nanney, LB, Davidson, JM. Proliferative responses to platelet-derived growth factor in young and old rat patellar tendon. Connect Tissue Res, 31(2), 171-7, 1995

Gates, R E, King, L E, Hanks, S K, Nanney, L B. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture. Cell Growth Differ, 5(8), 891-9, 1994

Gunaratne, P, Stoscheck, C, Gates, R E, Li, L, Nanney, L B, King, L E. Protein tyrosyl phosphatase-1B is expressed by normal human epidermis, keratinocytes, and A-431 cells and dephosphorylates substrates of the epidermal growth factor receptor. J Invest Dermatol, 103(5), 701-6, 1994

Nanney, L B, Coffey, R J, Ellis, D L. Expression and distribution of transforming growth factor-alpha within melanocytic lesions. J Invest Dermatol, 103(5), 707-14, 1994

Stricklin, G P, Li, L, Nanney, L B. Localization of mRNAs representing interstitial collagenase, 72-kda gelatinase, and TIMP in healing porcine burn wounds. J Invest Dermatol, 103(3), 352-8, 1994

Stricklin, G P, Nanney, L B. Immunolocalization of collagenase and TIMP in healing human burn wounds. J Invest Dermatol, 103(4), 488-92, 1994

Blessing, M, Nanney, L B, King, L E, Jones, C M, Hogan, B L. Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. Genes Dev, 7(2), 204-15, 1993

Dominey, A M, Wang, X J, King, L E, Nanney, L B, Gagne, T A, Sellheyer, K, Bundman, D S, Longley, M A, Rothnagel, J A, Greenhalgh, D A. Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ, 4(12), 1071-82, 1993

Durham, D R, Fortney, D Z, Nanney, L B. Preliminary evaluation of vibriolysin, a novel proteolytic enzyme composition suitable for the debridement of burn wound eschar. J Burn Care Rehabil, 14(5), 544-51, 1993

Fava, R A, Nanney, L B, Wilson, D, King, L E. Annexin-1 localization in human skin: possible association with cytoskeletal elements in keratinocytes of the stratum spinosum. J Invest Dermatol, 101(5), 732-7, 1993

Levine, J H, Moses, H L, Gold, L I, Nanney, L B. Spatial and temporal patterns of immunoreactive transforming growth factor beta 1, beta 2, and beta 3 during excisional wound repair. Am J Pathol, 143(2), 368-80, 1993 PMCID:1887040

Molina, P E, Eltayeb, K, Hourani, H, Okamura, K, Nanney, L B, Williams, P, Abumrad, N N. Hormonal and metabolic effects of neuroglucopenia. Brain Res, 614(1-2), 99-108, 1993

Quaglino, D, Fornieri, C, Nanney, L B, Davidson, J M. Extracellular matrix modifications in rat tissues of different ages. Correlations between elastin and collagen type I mRNA expression and lysyl-oxidase activity. Matrix, 13(6), 481-90, 1993

Stricklin, G P, Li, L, Jancic, V, Wenczak, B A, Nanney, L B. Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds. Am J Pathol, 143(6), 1657-66, 1993 PMCID:1887264

Tettelbach, W, Nanney, L, Ellis, D, King, L, Richmond, A. Localization of MGSA/GRO protein in cutaneous lesions. J Cutan Pathol, 20(3), 259-66, 1993

Wenczak, B, Nanney, LB. Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds. Wound Repair Regen, 1(4), 219-30, 1993

Ellis, D L, King, L E, Nanney, L B. Increased epidermal growth factor receptors in melanocytic lesions. J Am Acad Dermatol, 27(4), 539-46, 1992

Nanney, L B, Ellis, D L, Levine, J, King, L E. Epidermal growth factor receptors in idiopathic and virally induced skin diseases. Am J Pathol, 140(4), 915-25, 1992 PMCID:1886376

Nanney, L B, Gates, R E, Todderud, G, King, L E, Carpenter, G. Altered distribution of phospholipase C-gamma 1 in benign hyperproliferative epidermal diseases. Cell Growth Differ, 3(4), 233-9, 1992

Nanney, L B, Yates, R A, King, L E. Modulation of epidermal growth factor receptors in psoriatic lesions during treatment with topical EGF. J Invest Dermatol, 98(3), 296-301, 1992

Romano, M, Polk, W H, Awad, J A, Arteaga, C L, Nanney, L B, Wargovich, M J, Kraus, E R, Boland, C R, Coffey, R J. Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo. J Clin Invest, 90(6), 2409-21, 1992 PMCID:443397

Stoscheck, C M, Nanney, L B, King, L E. Quantitative determination of EGF-R during epidermal wound healing. J Invest Dermatol, 99(5), 645-9, 1992

Wenczak, B A, Lynch, J B, Nanney, L B. Epidermal growth factor receptor distribution in burn wounds. Implications for growth factor-mediated repair. J Clin Invest, 90(6), 2392-401, 1992 PMCID:443395

Birecree, E, King, L E, Nanney, L B. Epidermal growth factor and its receptor in the developing human nervous system. Brain Res Dev Brain Res, 60(2), 145-54, 1991

Davidson, J M, Nanney, L B, Broadley, K N, Whitsett, J S, Aquino, A M, Beccaro, M, Rastrelli, A. Hyaluronate derivatives and their application to wound healing: preliminary observations. Clin Mater, 8(1-2), 171-7, 1991

Fava, R A, Olsen, N J, Postlethwaite, A E, Broadley, K N, Davidson, J M, Nanney, L B, Lucas, C, Townes, A S. Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med, 173(5), 1121-32, 1991 PMCID:2118851

King, L E, Holbrook, K A, Stoscheck, C, Underwood, R A, Nanney, L B. Growth factor receptors and hair loss. J Invest Dermatol, 96(5), 79S, 1991

Quaglino, D, Nanney, L B, Ditesheim, J A, Davidson, J M. Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model. J Invest Dermatol, 97(1), 34-42, 1991

Reilly, M K, Perry, M O, Nanney, L B. True ablation of atheromatous plaques with laser energy. A phase I safety study. Ann Surg, 213(5), 440-4; discussion 444-5, 1991 PMCID:1358469

Yates, R A, Nanney, L B, Gates, R E, King, L E. Epidermal growth factor and related growth factors. Int J Dermatol, 30(10), 687-94, 1991

Ellis, D L, Nanney, L B, King, L E. Increased epidermal growth factor receptors in seborrheic keratoses and acrochordons of patients with the dysplastic nevus syndrome. J Am Acad Dermatol, 23(6 Pt 1), 1070-7, 1990

Fava, R A, Casey, T T, Wilcox, J, Pelton, R W, Moses, H L, Nanney, L B. Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules. Blood, 76(10), 1946-55, 1990

King, L E, Gates, R E, Stoscheck, C M, Nanney, L B. The EGF/TGF alpha receptor in skin. J Invest Dermatol, 94(6 Suppl), 164S-170S, 1990

King, L E, Gates, R E, Stoscheck, C M, Nanney, L B. Epidermal growth factor/transforming growth factor alpha receptors and psoriasis. J Invest Dermatol, 95(5), 10S-12S, 1990

King, LE, Gates, RE, Stoscheck, CM, Nanney, LB. Epidermal growth factor/transforming growth factor alpha receptors and psoriasis. J Invest Dermatol, 95(5 Suppl), 10S-2S, 1990

Nanney, L B. Epidermal and dermal effects of epidermal growth factor during wound repair. J Invest Dermatol, 94(5), 624-9, 1990

Nanney, L B, King, L E, Dale, B A. Epidermal growth factor receptors in genetically induced hyperproliferative skin disorders. Pediatr Dermatol, 7(4), 256-65, 1990

Nanney, L B, Stoscheck, C M, King, L E, Underwood, R A, Holbrook, K A. Immunolocalization of epidermal growth factor receptors in normal developing human skin. J Invest Dermatol, 94(6), 742-8, 1990

Nanney, L. B., Stoscheck, C. M., King, L. E., Underwood, R. A., and Holbrook, C. A. Immuno localization of epidermal growth factor receptors in normal developing human skin. J. Invest. Dermat., 94, 742-848, 1990

Quaglino, D, Nanney, L B, Kennedy, R, Davidson, J M. Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin. I. Excisional wound model. Lab Invest, 63(3), 307-19, 1990

Quaglino, D., Nanney, L. B., Kennedy, R., and Davidson, J. M. Transforming growth factor b stimulates wound healing and modulates extracellular matrix gene expression in pig skin. Lab. Invest., 63, 307-319 , 1990

Brown, G L, Nanney, L B, Griffen, J, Cramer, A B, Yancey, J M, Curtsinger, L J, Holtzin, L, Schultz, G S, Jurkiewicz, M J, Lynch, J B. Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med, 321(2), 76-9, 1989

Birecree, E, Whetsell, W O, Stoscheck, C, King, L E, Nanney, L B. Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease. J Neuropathol Exp Neurol, 47(5), 549-60, 1988

King, L E, Ellis, D L, Gates, R E, Inman, W H, Stoscheck, C M, Fava, R A, Nanney, L B. The role of epidermal growth factor in skin diseases. Am J Med Sci, 296(3), 154-8, 1988

Nanney, L B, Stoscheck, C M, King, L E. Characterization of binding and receptors for epidermal growth factor in smooth muscle. Cell Tissue Res, 254(1), 125-32, 1988

Werner, M H, Nanney, L B, Stoscheck, C M, King, L E. Localization of immunoreactive epidermal growth factor receptors in human nervous system. J Histochem Cytochem, 36(1), 81-6, 1988

Ellis, D L, Kafka, S P, Chow, J C, Nanney, L B, Inman, W H, McCadden, M E, King, L E. Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Tr??lat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes. N Engl J Med, 317(25), 1582-7, 1987

Healy, D A, Merrill, W H, Nanney, L B, Smith, B M. The influence of preservation techniques on prostacyclin biosynthesis in venous autografts. Curr Surg, 43(2), 103-5, 1986

Nanney, L B, Stoscheck, C M, Magid, M, King, L E. Altered [125I]epidermal growth factor binding and receptor distribution in psoriasis. J Invest Dermatol, 86(3), 260-5, 1986

Nanney, L. B., Stoscheck, C. M., and King, L. E. Altered 1251-epidermal growth factor binding and receptor distribution in psoriasis. J. Invest. Dermat., 86, 260-265, 1986

Rees, R S, Nanney, L B, Fleming, P, Cary, A. Tissue expansion: its role in traumatic below-knee amputations. Plast Reconstr Surg, 77(1), 133-7, 1986

Magid, M, Nanney, L B, Stoscheck, C M, King, L E. Epidermal growth factor binding and receptor distribution in term human placenta. Placenta, 6(6), 519-26, 1985

Rees, R S, Reilley, A F, Nanney, L B, Lynch, J B. Sacral pressure sores: treatment with island gluteus maximus musculocutaneous flaps. South Med J, 78(10), 1147-51, 1985

Nanney, L B, Magid, M, Stoscheck, C M, King, L E. Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol, 83(5), 385-93, 1984

Nanney, L B, McKanna, J A, Stoscheck, C M, Carpenter, G, King, L E. Visualization of epidermal growth factor receptors in human epidermis. J Invest Dermatol, 82(2), 165-9, 1984

Nanney, L. B., Magid, M., Stoscheck, C. M., and King, L. E. Epidermal growth factor binding and receptor distribution in normal human skin and appendages. J. Invest. Dermat., 385-393, 1984

Rees, R S, Nanney, L B, Yates, R A, King, L E. Interaction of brown recluse spider venom on cell membranes: the inciting mechanism. J Invest Dermatol, 83(4), 270-5, 1984

Nanney, L B, Newton, E D, Franklin, J D, Rees, R S, Lynch, J B. Venous endothelial changes after experimental cooling of free flaps. J Surg Res, 34(3), 271-8, 1983

Nanney, L B. Changes in the microvasculature of skin subjected to thermal injury. Burns Incl Therm Inj, 8(5), 321-7, 1982

Nanney, L B. Histochemical alterations in severely burned guinea pig skin. Plast Reconstr Surg, 68(5), 753-9, 1981

Nanney, L B. The effects of severe thermal injury on the glycosaminoglycans of guinea pig skin. J Invest Dermatol, 76(4), 227-30, 1981


Postdoctoral Position Available
No

Postdoctoral Position Details
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Updated Date
07/26/2013