Vanderbilt University School of Medicine

Lamb, Fred Sanford , MD, PhD
Professor of Pediatrics
Cornelius Vanderbilt Chair
Professor of Molecular Physiology and Biophysics

Lab Url: N/A

Phone Number: 615-936-1301


Lamb, Fred's picture

Office Address   Mailing Address

1065 Light Hall

Agarwal, HS, Hardison, DC, Saville, BR, Donahue, BS, Lamb, FS, Bichell, DP, Harris, ZL. Residual lesions in postoperative pediatric cardiac surgery patients receiving extracorporeal membrane oxygenation support. J Thorac Cardiovasc Surg, 147(1), 434-41, 2014.

Ganapathi, SB, Wei, SG, Zaremba, A, Lamb, FS, Shears, SB. Functional regulation of ClC-3 in the migration of vascular smooth muscle cells. Hypertension, 61(1), 174-9, 2013.

Garbrecht, MR, Lamb, FS. Placental HSD2 Expression and Activity Is Unaffected by Maternal Protein Consumption or Gender in C57BL/6 Mice. ISRN Endocrinol, 2013, 867938, 2013.

Lamb, FS, Hook, JS, Hilkin, BM, Huber, JN, Volk, AP, Moreland, JG. Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species. J Biol Chem, 287(15), 12395-404, 2012.

Roghair, RD, Volk, KA, Lamb, FS, Segar, JL. Impact of maternal dexamethasone on coronary PGE(2) production and prostaglandin-dependent coronary reactivity. Am J Physiol Regul Integr Comp Physiol, 303(5), R513-9, 2012.

Vucovich, M, Ehinger, N, Poole, SD, Lamb, FS, Reese, J. Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice. EJ Neonatol Res, 2(1), 13-24, 2012.

Bozeat, ND, Xiang, SY, Ye, LL, Yao, TY, Duan, ML, Burkin, DJ, Lamb, FS, Duan, DD. Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning. Cell Physiol Biochem, 28(6), 1265-78, 2011.

Chu, X, Filali, M, Stanic, B, Takapoo, M, Sheehan, A, Bhalla, R, Lamb, FS, Miller, FJ. A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation. Arterioscler Thromb Vasc Biol, 31(2), 345-51, 2011.

Roghair, RD, Wemmie, JA, Volk, KA, Scholz, TD, Lamb, FS, Segar, JL. Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice. Clin Sci (Lond), 121(10), 427-36, 2011.

Matsuda, JJ, Filali, MS, Collins, MM, Volk, KA, Lamb, FS. The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pH. J Biol Chem, 285(4), 2569-79, 2010.

Matsuda, JJ, Filali, MS, Moreland, JG, Miller, FJ, Lamb, FS. Activation of swelling-activated chloride current by tumor necrosis factor-alpha requires ClC-3-dependent endosomal reactive oxygen production. J Biol Chem, 285(30), 22864-73, 2010.

Miller, FJ, Chu, X, Stanic, B, Tian, X, Sharma, RV, Davisson, RL, Lamb, FS. A differential role for endocytosis in receptor-mediated activation of Nox1. Antioxid Redox Signal, 12(5), 583-93, 2010.

Volk, KA, Roghair, RD, Jung, F, Scholz, TD, Lamb, FS, Segar, JL. Coronary endothelial function and vascular smooth muscle proliferation are programmed by early-gestation dexamethasone exposure in sheep. Am J Physiol Regul Integr Comp Physiol, 298(6), R1607-14, 2010.

Lamb, FS, Moreland, JG, Miller, FJ. Electrophysiology of reactive oxygen production in signaling endosomes. Antioxid Redox Signal, 11(6), 1335-47, 2009.

Roghair, RD, Segar, JL, Volk, KA, Chapleau, MW, Dallas, LM, Sorenson, AR, Scholz, TD, Lamb, FS. Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice. Am J Physiol Regul Integr Comp Physiol, 296(3), R651-62, 2009.

von Bergen, NH, Koppenhafer, SL, Spitz, DR, Volk, KA, Patel, SS, Roghair, RD, Lamb, FS, Segar, JL, Scholz, TD. Fetal programming alters reactive oxygen species production in sheep cardiac mitochondria. Clin Sci (Lond), 116(8), 659-68, 2009.

George, CL, Goss, KL, Meyerholz, DK, Lamb, FS, Snyder, JM. Surfactant-associated protein A provides critical immunoprotection in neonatal mice. Infect Immun, 76(1), 380-90, 2008.

Matsuda, JJ, Filali, MS, Volk, KA, Collins, MM, Moreland, JG, Lamb, FS. Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent. Am J Physiol Cell Physiol, 294(1), C251-62, 2008.

Roghair, RD, Miller, FJ, Scholz, TD, Lamb, FS, Segar, JL. Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone. Pediatr Res, 63(4), 370-4, 2008.

Volk, AP, Heise, CK, Hougen, JL, Artman, CM, Volk, KA, Wessels, D, Soll, DR, Nauseef, WM, Lamb, FS, Moreland, JG. ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change. J Biol Chem, 283(49), 34315-26, 2008.

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