Vanderbilt University School of Medicine

Yin, Dengping , M.D., Ph.D.

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Phone Number: 615-343-6990


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A4108 MCN

CC2308 MCN A4108 MCN 37232

Ding, JW, Zhou, T, Ma, L, Yin, D, Shen, J, Ding, CP, Tang, IY, Byrne, GW, Chong, AS. Expression of complement regulatory proteins in accommodated xenografts induced by anti-alpha-Gal IgG1 in a rat-to-mouse model. Am J Transplant, 8(1), 32-40, 2008.

Ding, JW, Zhou, T, Zeng, H, Ma, L, Verbeek, JS, Yin, D, Shen, J, Chong, AS. Hyperacute rejection by anti-Gal IgG1, IgG2a, and IgG2b is dependent on complement and Fc-gamma receptors. J Immunol, 180(1), 261-8, 2008.

Li, Y, Ma, L, Yin, D, Shen, J, Chong, AS. Long-term control of alloreactive B cell responses by the suppression of T cell help. J Immunol, 180(9), 6077-84, 2008. PMCID:2605285

Ma, L, Xiang, Z, Sherrill, TP, Wang, L, Blackwell, TS, Williams, P, Chong, A, Chari, R, Yin, DP. Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation. Transplantation, 85(6), 903-10, 2008. PMCID:2632578

Manicassamy, S, Yin, D, Zhang, Z, Molinero, LL, Alegre, ML, Sun, Z. A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection. J Immunol, 181(1), 513-20, 2008. PMCID:2488962

Wang, R, Zhang, J, Guo, Z, Shen, L, Shang, A, Chen, Y, Yao, S, He, T, Yin, D, Tian, J. In-vivo PET imaging of implanted human retinal pigment epithelium cells in a Parkinson''s disease rat model. Nucl Med Commun, 29(5), 455-61, 2008.

Wang, T, Chen, L, Ahmed, E, Ma, L, Yin, D, Zhou, P, Shen, J, Xu, H, Wang, CR, Alegre, ML, Chong, AS. Prevention of allograft tolerance by bacterial infection with Listeria monocytogenes. J Immunol, 180(9), 5991-9, 2008. PMCID:2597467

Xiang, Z, Ma, LL, Manicassamy, S, Ganesh, BB, Williams, P, Chari, R, Chong, A, Yin, DP. CD4+ T cells are sufficient to elicit allograft rejection and major histocompatibility complex class I molecule is required to induce recurrent autoimmune diabetes after pancreas transplantation in mice. Transplantation, 85(8), 1205-11, 2008. PMCID:2632575

Chen, L, Wang, T, Zhou, P, Ma, L, Yin, D, Shen, J, Molinero, L, Nozaki, T, Phillips, T, Uematsu, S, Akira, S, Wang, CR, Fairchild, RL, Alegre, ML, Chong, A. TLR engagement prevents transplantation tolerance. Am J Transplant, 6(10), 2282-91, 2006.

Chong, AS, Shen, J, Tao, J, Yin, D, Kuznetsov, A, Hara, M, Philipson, LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science, 311(5768), 1774-5, 2006.

Yin, D, Ding, JW, Shen, J, Ma, L, Hara, M, Chong, AS. Liver ischemia contributes to early islet failure following intraportal transplantation: benefits of liver ischemic-preconditioning. Am J Transplant, 6(1), 60-8, 2006.

Yin, D, Tao, J, Lee, DD, Shen, J, Hara, M, Lopez, J, Kuznetsov, A, Philipson, LH, Chong, AS. Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen. Diabetes, 55(12), 3256-63, 2006.

Zeng, H, Waldman, WJ, Yin, DP, Knight, DA, Shen, J, Ma, L, Meister, GT, Chong, AS, Williams, JW. Mechanistic study of malononitrileamide FK778 in cardiac transplantation and CMV infection in rats. Transplantation, 79(1), 17-22, 2005.

Hara, M, Yin, D, Dizon, RF, Shen, J, Chong, AS, Bindokas, VP. A mouse model for studying intrahepatic islet transplantation. Transplantation, 78(4), 615-8, 2004.

Ogawa, H, Mohiuddin, MM, Yin, DP, Shen, J, Chong, AS, Galili, U. Mouse-heart grafts expressing an incompatible carbohydrate antigen. II. Transition from accommodation to tolerance. Transplantation, 77(3), 366-73, 2004.

Ogawa, H, Yin, DP, Galili, U. Induction of immune tolerance to a transplantation carbohydrate antigen by gene therapy with autologous lymphocytes transduced with adenovirus containing the corresponding glycosyltransferase gene. Gene Ther, 11(3), 292-301, 2004.

Yin, D, Zeng, H, Ma, L, Shen, J, Xu, H, Byrne, GW, Chong, AS. Cutting Edge: NK cells mediate IgG1-dependent hyperacute rejection of xenografts. J Immunol, 172(12), 7235-8, 2004.

Martin, MJ, Yin, D, Adams, C, Houtz, J, Shen, J, Chong, AS, Sharma, A, Byrne, GW, Wiseman, BS, Logan, JS. Skin graft survival in genetically identical cloned pigs. Cloning Stem Cells, 5(2), 117-21, 2003.

Mohiuddin, MM, Ogawa, H, Yin, DP, Galili, U. Tolerance induction to a mammalian blood group-like carbohydrate antigen by syngeneic lymphocytes expressing the antigen, II: tolerance induction on memory B cells. Blood, 102(1), 229-36, 2003.

Mohiuddin, MM, Ogawa, H, Yin, DP, Shen, J, Galili, U. Antibody-mediated accommodation of heart grafts expressing an incompatible carbohydrate antigen. Transplantation, 75(3), 258-62, 2003.

Ogawa, H, Yin, DP, Shen, J, Galili, U. Tolerance induction to a mammalian blood group-like carbohydrate antigen by syngeneic lymphocytes expressing the antigen. Blood, 101(6), 2318-20, 2003.

Xu, H, Yin, D, Naziruddin, B, Chen, L, Stark, A, Wei, Y, Lei, Y, Shen, J, Logan, JS, Byrne, GW, Chong, AS. The in vitro and in vivo effects of anti-galactose antibodies on endothelial cell activation and xenograft rejection. J Immunol, 170(3), 1531-9, 2003.

Yin, D, Dujovny, N, Ma, L, Varghese, A, Shen, J, Bishop, DK, Chong, AS. IFN-gamma production is specifically regulated by IL-10 in mice made tolerant with anti-CD40 ligand antibody and intact active bone. J Immunol, 170(2), 853-60, 2003.

Dujovny, N, Varghese, A, Shen, J, Yin, D, Ji, S, Ma, L, Finnegan, A, Chong, AS. Acute xenograft rejection mediated by antibodies produced independently of TH1/TH2 cytokine profiles. Am J Transplant, 2(6), 526-34, 2002.

Nathan, MJ, Yin, D, Eichwald, EJ, Bishop, DK. The immunobiology of inductive anti-CD40L therapy in transplantation: allograft acceptance is not dependent upon the deletion of graft-reactive T cells. Am J Transplant, 2(4), 323-32, 2002.

Tanemura, M, Ogawa, H, Yin, DP, Chen, ZC, DiSesa, VJ, Galili, U. Elimination of anti-Gal B cells by alpha-Gal ricin1. Transplantation, 73(12), 1859-68, 2002.

Yin, D, Ma, L, Shen, J, Byrne, GW, Logan, JS, Chong, AS. CTLA-41g in combination with anti-CD40L prolongs xenograft survival and inhibits anti-gal ab production in GT-Ko mice. Am J Transplant, 2(1), 41-7, 2002.

Yin, D, Ma, L, Varghese, A, Shen, J, Chong, AS. Intact active bone transplantation synergizes with anti-CD40 ligand therapy to induce B cell tolerance. J Immunol, 168(10), 5352-8, 2002.

Yin, D, Ma, L, Zeng, H, Shen, J, Chong, AS. Allograft tolerance induced by intact active bone co-transplantation and anti-CD40L monoclonal antibody therapy. Transplantation, 74(3), 345-54, 2002.

Yin, DP, Ma, LL, Sankary, HN, Shen, J, Zeng, H, Varghese, A, Chong, AS. Role of CD4+ and CD8+ T cells in the rejection of concordant pancreas xenografts. Transplantation, 74(9), 1236-41, 2002.

Tanemura, M, Yin, D, DiSesa, VJ, Galili, U. Preventing anti-Gal response in xenograft recipients by an alpha-Gal toxin. Transplant Proc, 33(1-2), 699-700, 2001.

Yin, DP, Sankary, HN, Ma, LL, Shen, J, Qin, Y, Blinder, L, Williams, JW, Chong, AS. Lewis rat pancreas, but not cardiac xenografts, are resistant to anti-gal antibody mediated hyperacute rejection. Transplantation, 71(10), 1385-9, 2001.

Chong, A, Blinder, L, Ma, L, Yin, D, Shen, J, Williams, JW, Byrne, G, Schwarz, A, Diamond, LS, Logan, JE. Anti-galactose-alpha(1,3) galactose antibody production in alpha1,3-galactosyltransferase gene knockout mice after xeno and allo transplantation. Transpl Immunol, 8(2), 129-37, 2000.

Chong, AS, Blinder, L, Ma, L, Yin, D, Shen, J, Williams, JW, Byrne, G, Schwarz, A, Diamond, LS, Logan, JE. Anti-galactose-alpha(1,3)Galactose antibody production in alpha1, 3-galactosyltransferase gene knockout mice after xeno- and allotransplantation. Transplant Proc, 32(5), 844-5, 2000.

Chong, AS, Ma, L, Yin, D, Shen, J, Blinder, L, XiuLong, X, Williams, J, Byrne, G, Diamond, L, Logan, J. Nondepleting anti-CD4 but not anti-CD8 antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1, 3-galactosyl-transferase knock-out mice. Transplant Proc, 32(5), 1005, 2000.

Chong, AS, Ma, L, Yin, D, Shen, J, Blinder, L, XiuLong, X, Williams, JW, Byrne, G, Diamond, LE, Logan, JS. Non-depleting anti-CD4, but not anti-CD8, antibody induces long-term survival of xenogeneic and allogeneic hearts in alpha1,3-galactosyltransferase knockout (GT-Ko) mice. Xenotransplantation, 7(4), 275-83, 2000.

Chong, AS, Ma, LL, Yin, D, Blinder, L, Shen, J, Williams, JW. Tolerance of T-independent xeno-antibody responses in the hamster-to-rat xenotransplantation model is species-restricted but not tissue-specific. Xenotransplantation, 7(1), 48-57, 2000.

Tanemura, M, Yin, D, Chong, A, Galili, U. Differential immune response to carbohydrate epitopes on allo- and xenografts: implications for accommodation. Transplant Proc, 32(5), 991-3, 2000.

Tanemura, M, Yin, D, Chong, AS, Galili, U. Differential immune responses to alpha-gal epitopes on xenografts and allografts: implications for accommodation in xenotransplantation. J Clin Invest, 105(3), 301-10, 2000. PMCID:377438

Yin, DP, Sankary, HN, Shen, J, Ma, LL, Blinder, L, Foster, P, Williams, JW, Chong, A. Efficacy of FK506, leflunomide, anti-CD4, and CTLA4IG treatments in rat to mouse pancreas xenograft transplantation. Transplant Proc, 32(5), 1003-4, 2000.

Sankary, HN, Yin, DP, Chong, AS, Ma, LL, Blinder, L, Shen, JK, Foster, P, Liu, LP, Li, C, Williams, JW. The portosystemic shunt protects liver against ischemic reperfusion injury. Transplantation, 68(7), 958-63, 1999.

Krieger, NR, Yuh, D, McIntyre, WB, Flavin, TF, Yin, D, Robbins, R, Fathman, CG. Prolongation of cardiac graft survival with anti-CD4Ig plus hCTLA4Ig in primates. J Surg Res, 76(2), 174-8, 1998.

Sankary, HN, Yin, DP, Chong, AS, Ma, LL, Blinder, L, Shen, JK, Foster, P, Williams, JW. FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation. Transplantation, 66(7), 832-7, 1998.

Yin, D, Ma, LL, Blinder, L, Shen, J, Sankary, H, Williams, JW, Chong, AS. Induction of species-specific host accommodation in the hamster-to-rat xenotransplantation model. J Immunol, 161(4), 2044-51, 1998.

Yin, DP, Sankary, HN, Chong, AS, Ma, LL, Shen, J, Foster, P, Williams, JW. Protective effect of ischemic preconditioning on liver preservation-reperfusion injury in rats. Transplantation, 66(2), 152-7, 1998.

Yin, DP, Sankary, HN, Talor-Edwards, C, Chong, AS, Foster, P, Shen, J, Ma, LL, Williams, JW, Fathman, CG. Anti-CD4 therapy in combined heart-kidney, heart-liver, and heart-small bowel allotransplants in high-responder rats. Transplantation, 66(1), 1-5, 1998.

Chong, AS, Ma, LL, Shen, J, Blinder, L, Yin, DP, Williams, JW. Modification of humoral responses by the combination of leflunomide and cyclosporine in Lewis rats transplanted with hamster hearts. Transplantation, 64(12), 1650-7, 1997.

Guo, Z, Chong, AS, Tian, Y, Shen, J, Yin, D, Mital, D, Foster, P, Sankary, H, McChesney, L, Jensik, S, Williams, JW. Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice. Transplant Proc, 29(4), 2155, 1997.

Yin, D, Zhang, X, Feng, Y, Cao, B, Li, W, Qian, H, Fu, T, Wu, Z. Regulation of rhTNF in abdominal cavity to the expression of C-erbB-2 of ovarian cancer nude mice ascites tumor. Chin Med J (Engl), 110(4), 311-2, 1997.

Yin, DP, Sankary, HN, Chong, AS, Blinder, L, Ma, LL, Williams, JW. Effect of anti-CD4 monoclonal antibody combined with human CTLA4Ig on the survival of hamster liver and heart xenografts in Lewis rats. Transplantation, 64(2), 317-21, 1997.

Krieger, NR, Yin, DP, Fathman, CG. CD4+ but not CD8+ cells are essential for allorejection. J Exp Med, 184(5), 2013-8, 1996. PMCID:2192869

Yin, DP, Sankary, HN, Williams, J, Krieger, N, Fathman, CG. Induction of tolerance to small bowel allografts in high-responder rats by combining anti-CD4 with CTLA4Ig. Transplantation, 62(11), 1537-9, 1996.

Zeng, D, Ready, A, Huie, P, Hayamizu, K, Holm, B, Yin, D, Sibley, RK, Strober, S. Mechanisms of tolerance to rat heart allografts using posttransplant TLI. Changes in cytokine expression. Transplantation, 62(4), 510-7, 1996.

Yin, D, Fathman, CG. Induction of tolerance to heart allografts in high responder rats by combining anti-CD4 with CTLA4Ig. J Immunol, 155(4), 1655-9, 1995.

Yin, D, Fathman, CG. Tissue-specific effects of anti-CD4 therapy in induction of allograft unresponsiveness in high and low responder rats. Transpl Immunol, 3(3), 258-64, 1995.

Yin, D, Fathman, CG. CD4-positive suppressor cells block allotransplant rejection. J Immunol, 154(12), 6339-45, 1995.

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