Vanderbilt University School of Medicine

Pantel, Jacques , PhD
Adjoint Associate Professor of Molecular Physiology and Biophysics

Lab Url: N/A

Phone Number: 67091


Pantel, Jacques's picture

Office Address   Mailing Address

8425 MRBIV

MPB department 702 Light Hall 37232

Research Keywords
Endocrinology, human genetics, mutation, neuroscience, pharmacology, receptor.

Research Specialty
Human molecular genetics, molecular pharmacology of G protein-coupled receptors, somatic growth disorders, eating disorders.

Pantel, J, Williams, SY, Mi, D, Sebag, J, Corbin, JD, Weaver, CD, Cone, RD. Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay. Eur J Pharmacol, , , 2011.

Pantel, J, Legendre, M, Nivot, S, Morisset, S, Vie-Luton, MP, le Bouc, Y, Epelbaum, J, Amselem, S. Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor. J Clin Endocrinol Metab, 94(11), 4334-41, 2009.

Pantel, J, Legendre, M, Cabrol, S, Hilal, L, Hajaji, Y, Morisset, S, Nivot, S, Vie-Luton, MP, Grouselle, D, de Kerdanet, M, Kadiri, A, Epelbaum, J, Le Bouc, Y, Amselem, S. Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature. J Clin Invest, 116(3), 760-8, 2006. PMCID:1386106

Lacroix, MC, Guibourdenche, J, Fournier, T, Laurendeau, I, Igout, A, Goffin, V, Pantel, J, Tsatsaris, V, Evain-Brion, D. Stimulation of human trophoblast invasion by placental growth hormone. Endocrinology, 146(5), 2434-44, 2005.

Amazit, L, Alj, Y, Tyagi, RK, Chauchereau, A, Loosfelt, H, Pichon, C, Pantel, J, Foulon-Guinchard, E, Leclerc, P, Milgrom, E, Guiochon-Mantel, A. Subcellular localization and mechanisms of nucleocytoplasmic trafficking of steroid receptor coactivator-1. J Biol Chem, 278(34), 32195-203, 2003.

Pantel, J, Grulich-Henn, J, Bettendorf, M, Strasburger, CJ, Heinrich, U, Amselem, S. Heterozygous nonsense mutation in exon 3 of the growth hormone receptor (GHR) in severe GH insensitivity (Laron syndrome) and the issue of the origin and function of the GHRd3 isoform. J Clin Endocrinol Metab, 88(4), 1705-10, 2003.

Machinis, K, Pantel, J, Netchine, I, L??ger, J, Camand, OJ, Sobrier, ML, Dastot-Le Moal, F, Duquesnoy, P, Abitbol, M, Czernichow, P, Amselem, S. Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4. Am J Hum Genet, 69(5), 961-8, 2001. PMCID:1274372

Couzinet, B, Pantel, J, Chanson, P, Young, J, Brailly, S, Huhtaniemi, IT, Bidart, JM, Schaison, G. Measurement of plasma free luteinizing hormone beta-subunit in women. J Clin Endocrinol Metab, 85(6), 2293-8, 2000.

Girodon-Boulandet, E, Pantel, J, Cazeneuve, C, Gijn, MV, Vidaud, D, Lemay, S, Martin, J, Zeller, J, Revuz, J, Goossens, M, Amselem, S, Wolkenstein, P. NF1 gene analysis focused on CpG-rich exons in a cohort of 93 patients with neurofibromatosis type 1. Hum Mutat, 16(3), 274-5, 2000.

Pantel, J, Machinis, K, Sobrier, ML, Duquesnoy, P, Goossens, M, Amselem, S. Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution. J Biol Chem, 275(25), 18664-9, 2000.

Papin, S, Duquesnoy, P, Cazeneuve, C, Pantel, J, Coppey-Moisan, M, Dargemont, C, Amselem, S. Alternative splicing at the MEFV locus involved in familial Mediterranean fever regulates translocation of the marenostrin/pyrin protein to the nucleus. Hum Mol Genet, 9(20), 3001-9, 2000.

Pantel, J, Robert, P, Troalen, F, Kujas, M, Bellet, D, Bidart, JM. Characterization of human lutropin carboxyl-terminus isoforms. Endocrinology, 139(2), 527-33, 1998.

Chanson, P, Pantel, J, Young, J, Couzinet, B, Bidart, JM, Schaison, G. Free luteinizing-hormone beta-subunit in normal subjects and patients with pituitary adenomas. J Clin Endocrinol Metab, 82(5), 1397-402, 1997.

Pantel, J, Robert, P, Troalen, F, Chanson, P, Schaison, G, Bellet, D, Bidart, JM. Characterization of a monoclonal antibody reacting with the free human luteinizing hormone beta-subunit. J Endocrinol, 151(2), 251-8, 1996.

Remy, JJ, Couture, L, Pantel, J, Haertl??, T, Rabesona, H, Bozon, V, Pajot-Augy, E, Robert, P, Troalen, F, Salesse, R, Bidart, JM. Mapping of HCG-receptor complexes. Mol Cell Endocrinol, 125(1-2), 79-91, 1996.

Robert, P, Pantel, J, Troalen, F, Bellet, D, Bidart, JM. Immunochemical mapping of human lutropin: II. Characterization of two monoclonal antipeptide antibodies reacting with the native beta-subunit. Mol Cell Endocrinol, 101(1-2), 21-8, 1994.

Pantel, J, Remy, JJ, Salesse, R, Jolivet, A, Bidart, JM. Unmasking of an immunoreactive site on the alpha subunit of human choriogonadotropin bound to the extracellular domain of its receptor. Biochem Biophys Res Commun, 195(2), 588-93, 1993.

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