Vanderbilt University School of Medicine

Koethe, John Robert , MD
Assistant Professor of Medicine

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Email Address:john.r.koethe

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S-2104 MCN

A2200-MCN 37232-2582

Clinical Research Description
Dr. Koethe received his M.D. degree from Yale University in 2004, followed by a residency at Johns Hopkins Hospital and a clinical fellowship in infectious diseases at Vanderbilt University. He was a NIH/Fogarty International Clinical Research Fellow at the Centre for Infectious Diseases Research in Zambia from 2008 to 2009. Dr. Koethea??s research interests include the impact of both undernutrition and obesity on the response to antiretroviral therapy, immune function, and health outcomes among HIV-infected adults, and the role of nutritional supplementation as a component of HIV treatment in resource-limited international settings.

Koethe, JR, Bian, A, Shintani, AK, Boger, MS, Mitchell, VJ, Erdem, H, Hulgan, T. Serum Leptin Level Mediates the Association of Body Composition and Serum C-Reactive Protein in HIV-Infected Persons on Antiretroviral Therapy. AIDS Res Hum Retroviruses, , , 2012.

Koethe, JR, Blevins, M, Bosire, C, Nyirenda, C, Kabagambe, EK, Mwango, A, Kasongo, W, Zulu, I, Shepherd, BE, Heimburger, DC. Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa. Public Health Nutr, , 1-10, 2012.

Menge, TJ, Koethe, JR, Jenkins, CA, Wright, PW, Shinar, AA, Miller, GG, Holt, GE. Acute Kidney Injury After Placement of an Antibiotic-Impregnated Cement Spacer During Revision Total Knee Arthroplasty. J Arthroplasty, , , 2012.

Koethe, JR, Blevins, M, Nyirenda, C, Kabagambe, EK, Shepherd, BE, Wester, CW, Zulu, I, Chiasera, JM, Mulenga, LB, Mwango, A, Heimburger, DC. Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia. J Int AIDS Soc, 14, 19, 2011. PMCID:3094357

Koethe, JR, Jenkins, CA, Shepherd, BE, Stinnette, SE, Sterling, TR. An optimal body mass index range associated with improved immune reconstitution among HIV-infected adults initiating antiretroviral therapy. Clin Infect Dis, 53(9), 952-60, 2011.

Wester, CW, Koethe, JR, Shepherd, BE, Stinnette, SE, Rebeiro, PF, Kipp, AM, Hong, H, Bussmann, H, Gaolathe, T, McGowan, CC, Sterling, TR, Marlink, RG. Non-AIDS-defining events among HIV-1-infected adults receiving combination antiretroviral therapy in resource-replete versus resource-limited urban setting. AIDS, 25(12), 1471-9, 2011. PMCID:3188442

Heimburger, DC, Koethe, JR, Nyirenda, C, Bosire, C, Chiasera, JM, Blevins, M, Munoz, AJ, Shepherd, BE, Potter, D, Zulu, I, Chisembele-Taylor, A, Chi, BH, Stringer, JS, Kabagambe, EK. Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study. PLoS One, 5(5), e10687, 2010. PMCID:2872675

Koethe, JR, Heimburger, DC. Nutritional aspects of HIV-associated wasting in sub-Saharan Africa. Am J Clin Nutr, 91(4), 1138S-1142S, 2010. PMCID:2844686

Koethe, JR, Limbada, MI, Giganti, MJ, Nyirenda, CK, Mulenga, L, Wester, CW, Chi, BH, Stringer, JS. Early immunologic response and subsequent survival among malnourished adults receiving antiretroviral therapy in Urban Zambia. AIDS, 24(13), 2117-21, 2010. PMCID:2919155

Koethe, JR, Lukusa, A, Giganti, MJ, Chi, BH, Nyirenda, CK, Limbada, MI, Banda, Y, Stringer, JS. Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia. J Acquir Immune Defic Syndr, 53(4), 507-13, 2010. PMCID:2844686

Koethe, JR, Westfall, AO, Luhanga, DK, Clark, GM, Goldman, JD, Mulenga, PL, Cantrell, RA, Chi, BH, Zulu, I, Saag, MS, Stringer, JS. A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics. PLoS One, 5(3), e9680, 2010. PMCID:2837376

Koethe, JR, Chi, BH, Megazzini, KM, Heimburger, DC, Stringer, JS. Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings. Clin Infect Dis, 49(5), 787-98, 2009. PMCID:3092426

Koethe, JR, Moore, RD, Wagner, KR. Physician specialization and women''s primary care services in an urban HIV clinic. AIDS Patient Care STDS, 22(5), 373-80, 2008. PMCID:2597508

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