Vanderbilt University School of Medicine

Cooper, William O. , M.D., M.P.H.
Professor of Pediatrics
Professor of Health Policy
Cornelius Vanderbilt Chair

Lab Url: http://www.vanderbiltchildrens.com/interior.php?mid=1858&did=1668

Phone Number: 615-936-2430

Email Address:william.cooper@vanderbilt.edu

Cooper, William's picture

Office Address   Mailing Address

Suite 313 Oxford House, 1313 21st Avenue South, Nashville, TN 37232-4313

Department of Pediatrics Suite 313 Oxford House, 1313 21st Avenue South 37232-4313


Research Description
Dr. Cooper is a pharmacoepidemiologist with a focus on the effects of psychotropic medications in chidlren and adverse effects of prescription medication use during pregnancy. Dr. Cooper has achieved national and international recognition for his work in using computerized databases to ask and answer important questions of drug safety. His work has been funded by the National Institutes of Health, the Agency for Healthcare Research and Quality, the Food and Drug Administration, and national foundations.

Publications
Andrade, SE, Scott, PE, Davis, RL, Li, DK, Getahun, D, Cheetham, TC, Raebel, MA, Toh, S, Dublin, S, Pawloski, PA, Hammad, TA, Beaton, SJ, Smith, DH, Dashevsky, I, Haffenreffer, K, Cooper, WO. Validity of health plan and birth certificate data for pregnancy research. Pharmacoepidemiol Drug Saf, 22(1), 7-15, 2013.

Avalos, LA, Chen, H, Yang, C, Andrade, SE, Cooper, WO, Cheetham, CT, Davis, RL, Dublin, S, Hammad, TA, Kaplan, S, Pawloski, PA, Raebel, MA, Scott, PE, Smith, DH, Toh, S, Li, DK. The Prevalence and Trends of Antiviral Medication Use During Pregnancy in the US: A Population-Based Study of 664,297 Deliveries in 2001-2007. Matern Child Health J, , , 2013.

Bobo, WV, Cooper, WO, Stein, CM, Olfson, M, Graham, D, Daugherty, J, Fuchs, DC, Ray, WA. Antipsychotics and the risk of type 2 diabetes mellitus in children and youth. JAMA Psychiatry, 70(10), 1067-75, 2013.

Callahan, ST, Fuchs, DC, Shelton, RC, Balmer, LS, Dudley, JA, Gideon, PS, Deranieri, MM, Stratton, SM, Williams, CL, Ray, WA, Cooper, WO. Identifying suicidal behavior among adolescents using administrative claims data. Pharmacoepidemiol Drug Saf, 22(7), 769-75, 2013.

Eckrich, MJ, Wang, WC, Yang, E, Arbogast, PG, Morrow, A, Dudley, JA, Ray, WA, Cooper, WO. Adherence to transcranial Doppler screening guidelines among children with sickle cell disease. Pediatr Blood Cancer, 60(2), 270-4, 2013.

Epstein, RA, Bobo, WV, Martin, PR, Morrow, JA, Wang, W, Chandrasekhar, R, Cooper, WO. Increasing pregnancy-related use of prescribed opioid analgesics. Ann Epidemiol, 23(8), 498-503, 2013.

Epstein, RA, Bobo, WV, Shelton, RC, Arbogast, PG, Morrow, JA, Wang, W, Chandrasekhar, R, Cooper, WO. Increasing use of atypical antipsychotics and anticonvulsants during pregnancy. Pharmacoepidemiol Drug Saf, 22(7), 794-801, 2013.

Johnson, KE, Beaton, SJ, Andrade, SE, Cheetham, TC, Scott, PE, Hammad, TA, Dashevsky, I, Cooper, WO, Davis, RL, Pawloski, PA, Raebel, MA, Smith, DH, Toh, S, Li, DK, Haffenreffer, K, Dublin, S. Methods of linking mothers and infants using health plan data for studies of pregnancy outcomes. Pharmacoepidemiol Drug Saf, 22(7), 776-82, 2013.

Li, Q, Andrade, SE, Cooper, WO, Davis, RL, Dublin, S, Hammad, TA, Pawloski, PA, Pinheiro, SP, Raebel, MA, Scott, PE, Smith, DH, Dashevsky, I, Haffenreffer, K, Johnson, KE, Toh, S. Validation of an algorithm to estimate gestational age in electronic health plan databases. Pharmacoepidemiol Drug Saf, 22(5), 524-32, 2013.

Lo Re, V, Haynes, K, Goldberg, D, Forde, KA, Carbonari, DM, Leidl, KB, Hennessy, S, Reddy, KR, Pawloski, PA, Daniel, GW, Cheetham, TC, Iyer, A, Coughlin, KO, Toh, S, Boudreau, DM, Selvam, N, Cooper, WO, Selvan, MS, Vanwormer, JJ, Avigan, MI, Houstoun, M, Zornberg, GL, Racoosin, JA, Shoaibi, A. Validity of diagnostic codes to identify cases of severe acute liver injury in the U.S. Food and Drug Administration''s Mini-Sentinel Distributed Database. Pharmacoepidemiol Drug Saf, 22(8), 861-72, 2013.

Ray, WA, Murray, KT, Kawai, V, Graham, DJ, Cooper, WO, Hall, K, Michael Stein, C. Propoxyphene and the risk of out-of-hospital death. Pharmacoepidemiol Drug Saf, 22(4), 403-12, 2013.

Sidney, S, Cheetham, TC, Connell, FA, Ouellet-Hellstrom, R, Graham, DJ, Davis, D, Sorel, M, Quesenberry, CP, Cooper, WO. Recent combined hormonal contraceptives (CHCs) and the risk of thromboembolism and other cardiovascular events in new users. Contraception, 87(1), 93-100, 2013.

Toh, S, Baker, MA, Brown, JS, Kornegay, C, Platt, R, , . Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration''s Mini-Sentinel program. JAMA Intern Med, 173(9), 817-9, 2013.

Toh, S, Li, Q, Cheetham, TC, Cooper, WO, Davis, RL, Dublin, S, Hammad, TA, Li, DK, Pawloski, PA, Pinheiro, SP, Raebel, MA, Scott, PE, Smith, DH, Bobo, WV, Lawrence, JM, Dashevsky, I, Haffenreffer, K, Avalos, LA, Andrade, SE. Prevalence and trends in the use of antipsychotic medications during pregnancy in the U.S., 2001-2007: a population-based study of 585,615 deliveries. Arch Womens Ment Health, 16(2), 149-57, 2013.

Bobo, WV, Cooper, WO, Stein, CM, Olfson, M, Mounsey, J, Daugherty, J, Ray, WA. Positive predictive value of a case definition for diabetes mellitus using automated administrative health data in children and youth exposed to antipsychotic drugs or control medications: a Tennessee Medicaid study. BMC Med Res Methodol, 12, 128, 2012.

Bobo, WV, Davis, RL, Toh, S, Li, DK, Andrade, SE, Cheetham, TC, Pawloski, P, Dublin, S, Pinheiro, S, Hammad, T, Scott, PE, Epstein Jr, RA, Arbogast, PG, Morrow, JA, Dudley, JA, Lawrence, JM, Avalos, LA, Cooper, WO. Trends in the Use of Antiepileptic Drugs among Pregnant Women in the US, 2001-2007: A Medication Exposure in Pregnancy Risk Evaluation Program Study. Paediatr Perinat Epidemiol, 26(6), 578-588, 2012.

Curtis, LH, Weiner, MG, Boudreau, DM, Cooper, WO, Daniel, GW, Nair, VP, Raebel, MA, Beaulieu, NU, Rosofsky, R, Woodworth, TS, Brown, JS. Design considerations, architecture, and use of the Mini-Sentinel distributed data system. Pharmacoepidemiol Drug Saf, 21 Suppl 1, 23-31, 2012.

Hayes, RM, Wu, P, Shelton, RC, Cooper, WO, Dupont, WD, Mitchel, E, Hartert, TV. Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies. Am J Obstet Gynecol, 207(1), 49.e1-9, 2012.

Kawai, VK, Murray, KT, Stein, CM, Cooper, WO, Graham, DJ, Hall, K, Ray, WA. Validation of a computer case definition for sudden cardiac death in opioid users. BMC Res Notes, 5, 473, 2012.

Andrade, SE, Davis, RL, Cheetham, TC, Cooper, WO, Li, DK, Amini, T, Beaton, SJ, Dublin, S, Hammad, TA, Pawloski, PA, Raebel, MA, Smith, DH, Staffa, JA, Toh, S, Dashevsky, I, Haffenreffer, K, Lane, K, Platt, R, Scott, PE. Medication Exposure in Pregnancy Risk Evaluation Program. Matern Child Health J, , , 2011.

Bobo, WV, Cooper, WO, Epstein, RA, Arbogast, PG, Mounsey, J, Ray, WA. Positive predictive value of automated database records for diabetic ketoacidosis (DKA) in children and youth exposed to antipsychotic drugs or control medications: a tennessee medicaid study. BMC Med Res Methodol, 11, 157, 2011. PMCID:3235973

Cooper, WO, Gitlin, JD. Commentary: charting a course for success: excellence in clinical care and discovery in academic departments. Acad Med, 86(5), 544-5, 2011.

Cooper, WO, Habel, LA, Sox, CM, Chan, KA, Arbogast, PG, Cheetham, TC, Murray, KT, Quinn, VP, Stein, CM, Callahan, ST, Fireman, BH, Fish, FA, Kirshner, HS, O''Duffy, A, Connell, FA, Ray, WA. ADHD Drugs and Serious Cardiovascular Events in Children and Young Adults. N Engl J Med, , , 2011.

Darbar, M, Emans, SJ, Harris, ZL, Brown, NJ, Scott, TA, Cooper, WO. Part-time physician faculty in a pediatrics department: a study of equity in compensation and academic advancement. Acad Med, 86(8), 968-73, 2011.

Habel, LA, Cooper, WO, Sox, CM, Chan, KA, Fireman, BH, Arbogast, PG, Cheetham, TC, Quinn, VP, Dublin, S, Boudreau, DM, Andrade, SE, Pawloski, PA, Raebel, MA, Smith, DH, Achacoso, N, Uratsu, C, Go, AS, Sidney, S, Nguyen-Huynh, MN, Ray, WA, Selby, JV. ADHD medications and risk of serious cardiovascular events in young and middle-aged adults. JAMA, 306(24), 2673-83, 2011.

Hysinger, EB, Callahan, ST, Caples, TL, Fuchs, DC, Shelton, R, Cooper, WO. Suicidal Behavior Differs Among Early and Late Adolescents Treated With Antidepressant Agents. Pediatrics, , , 2011.

Williams, DJ, Cooper, WO, Kaltenbach, LA, Dudley, JA, Kirschke, DL, Jones, TF, Arbogast, PG, Griffin, MR, Creech, CB. Comparative Effectiveness of Antibiotic Treatment Strategies for Pediatric Skin and Soft-Tissue Infections. Pediatrics, , , 2011.

Callahan, ST, Cooper, WO. Changes in ambulatory health care use during the transition to young adulthood. J Adolesc Health, 46(5), 407-13, 2010.

Jules, A, Kaltenbach, LA, Arbogast, PG, Caples, TL, Po''e, EK, Cooper, WO. Use of drugs known to cause fetal harm among women delivering infants in Haiti. Acad Pediatr, 10(6), 395-9, 2010.

Warren, MD, Arbogast, PG, Dudley, JA, Kaltenbach, L, Ray, WA, Wang, WC, Cooper, WO. Adherence to prophylactic antibiotic guidelines among Medicaid infants with sickle cell disease. Arch Pediatr Adolesc Med, 164(3), 298-9, 2010.

Cooper, WO, Hernandez-Diaz, S, Arbogast, PG, Dudley, JA, Dyer, SM, Gideon, PS, Hall, KS, Kaltenbach, LA, Ray, WA. Antibiotics potentially used in response to bioterrorism and the risk of major congenital malformations. Paediatr Perinat Epidemiol, 23(1), 18-28, 2009.

Pont, SJ, Grijalva, CG, Griffin, MR, Scott, TA, Cooper, WO. National rates of diarrhea-associated ambulatory visits in children. J Pediatr, 155(1), 56-61, 2009.

Bowen, ME, Ray, WA, Arbogast, PG, Ding, H, Cooper, WO. Increasing exposure to angiotensin-converting enzyme inhibitors in pregnancy. Am J Obstet Gynecol, 198(3), 291.e1-5, 2008. PMCID:2666985

Carpenter, LR, Pont, SJ, Cooper, WO, Griffin, MR, Dudley, JA, Arbogast, P, Schaffner, W, Jones, TF. Stool cultures and antimicrobial prescriptions related to infectious diarrhea. J Infect Dis, 197(12), 1709-12, 2008. PMCID:2666985

Carroll, KN, Arbogast, PG, Dudley, JA, Cooper, WO. Increase in incidence of medically treated thyroid disease in children with Down Syndrome after rerelease of American Academy of Pediatrics Health Supervision guidelines. Pediatrics, 122(2), e493-8, 2008. PMCID:2666985

Cooper, WO, Hernandez-Diaz, S, Gideon, P, Dyer, SM, Hall, K, Dudley, J, Cevasco, M, Thompson, AB, Ray, WA. Positive predictive value of computerized records for major congenital malformations. Pharmacoepidemiol Drug Saf, 17(5), 455-60, 2008. PMCID:2666985

Cooper, WO, Ray, WA, Arbogast, PG, Garrison, M, Dudley, JA, Christakis, DA. Health plan notification and feedback to providers is associated with increased filling of preventer medications for children with asthma enrolled in Medicaid. J Pediatr, 152(4), 481-8, 2008. PMCID:2666985

Pont, SJ, Carpenter, LR, Griffin, MR, Jones, TF, Schaffner, W, Dudley, JA, Arbogast, PG, Cooper, WO. Trends in healthcare usage attributable to diarrhea, 1995-2004. J Pediatr, 153(6), 777-82, 2008.

Warren, MD, Cooper, WO. Honey improves cough in children compared to no treatment. J Pediatr, 152(5), 739-40, 2008. PMCID:2666985

Callahan, ST, Cooper, WO. Continuity of health insurance coverage among young adults with disabilities. Pediatrics, 119(6), 1175-80, 2007. PMCID:2666985

Collins, SR, Griffin, MR, Arbogast, PG, Walsh, WF, Rush, MR, Carter, BS, Dudley, J, Cooper, WO. The rising prevalence of gastroschisis and omphalocele in Tennessee. J Pediatr Surg, 42(7), 1221-4, 2007. PMCID:2666985

Cooper, WO. Clinical implications of increased congenital malformations after first trimester exposures to angiotensin-converting enzyme inhibitors. J Cardiovasc Nurs, 23(1), 20-4, 2007. PMCID:2666985

Cooper, WO, Willy, ME, Pont, SJ, Ray, WA. Increasing use of antidepressants in pregnancy. Am J Obstet Gynecol, 196(6), 544.e1-5, 2007. PMCID:2666985

Enriquez, R, Griffin, MR, Carroll, KN, Wu, P, Cooper, WO, Gebretsadik, T, Dupont, WD, Mitchel, EF, Hartert, TV. Effect of maternal asthma and asthma control on pregnancy and perinatal outcomes. J Allergy Clin Immunol, 120(3), 625-30, 2007. PMCID:2666985

Gunn, VL, Phillippi, RM, Cooper, WO. Improvement in booster seat use in Tennessee. Pediatrics, 119(1), e131-6, 2007.

Kurian, BT, Ray, WA, Arbogast, PG, Fuchs, DC, Dudley, JA, Cooper, WO. Effect of regulatory warnings on antidepressant prescribing for children and adolescents. Arch Pediatr Adolesc Med, 161(7), 690-6, 2007. PMCID:2666985

Warren, MD, Pont, SJ, Barkin, SL, Callahan, ST, Caples, TL, Carroll, KN, Plemmons, GS, Swan, RR, Cooper, WO. The effect of honey on nocturnal cough and sleep quality for children and their parents. Arch Pediatr Adolesc Med, 161(12), 1149-53, 2007. PMCID:2666985

Callahan, ST, Cooper, WO. Access to health care for young adults with disabling chronic conditions. Arch Pediatr Adolesc Med, 160(2), 178-82, 2006.

Callahan, ST, Hickson, GB, Cooper, WO. Health care access of Hispanic young adults in the United States. J Adolesc Health, 39(5), 627-33, 2006.

Cooper, WO, Hernandez-Diaz, S, Arbogast, PG, Dudley, JA, Dyer, S, Gideon, PS, Hall, K, Ray, WA. Major congenital malformations after first-trimester exposure to ACE inhibitors. N Engl J Med, 354(23), 2443-51, 2006.

Bowen, ME, Poehling, KA, Gunn, VL, Carroll, KN, Callahan, ST, Arbogast, PG, Cooper, WO. Does the use of oxycodone affect diagnostic accuracy in children with acute abdominal pain. Arch Pediatr Adolesc Med, 159(4), 326-8, 2005.

Callahan, ST, Cooper, WO. Uninsurance and health care access among young adults in the United States. Pediatrics, 116(1), 88-95, 2005.

Carroll, KN, Cooper, WO, Blackford, JU, Hickson, GB. Characteristics of families that complain following pediatric emergency visits. Ambul Pediatr, 5(6), 326-31, 2005.

Cooper, WO. Validity of maternal report of acute health care for children: evaluating proxy interview responses. Arch Pediatr Adolesc Med, 159(2), 193-4, 2005.

Cooper, WO, Arbogast, PG, Ding, H, Hickson, GB, Fuchs, DC, Ray, WA. Trends in prescribing of antipsychotic medications for US children. Ambul Pediatr, 6(2), 79-83, 2005.

Cooper, WO, Arbogast, PG, Hickson, GB, Daugherty, JR, Ray, WA. Gaps in enrollment from a Medicaid managed care program: effects on emergency department visits and hospitalizations for children with asthma. Med Care, 43(7), 718-25, 2005.

Gunn, VL, Hickson, GB, Cooper, WO. Factors affecting pediatricians'' reporting of suspected child maltreatment. Ambul Pediatr, 5(2), 96-101, 2005.

Gunn, VL, Phillippi, RM, Cooper, WO. Racial differences in child safety restraint use in Tennessee. Inj Prev, 11(6), 340-2, 2005. PMCID:1730290

Shankar, SM, Arbogast, PG, Mitchel, E, Cooper, WO, Wang, WC, Griffin, MR. Medical care utilization and mortality in sickle cell disease: A population-based study. Am J Hematol, 80(4), 262-70, 2005.

Butler, K, Cooper, WO. Adherence of pediatric asthma patients with oral corticosteroid prescriptions following pediatric emergency department visit or hospitalization. Pediatr Emerg Care, 20(11), 730-5, 2004.

Callahan, S Todd, Cooper, William O. Gender and uninsurance among young adults in the United States. Pediatrics, 113(2), 291-7, 2004.

Cooper, WO, Hickson, GB, Fuchs, C, Arbogast, PG, Ray, WA. New users of antipsychotic medications among children enrolled in TennCare. Arch Pediatr Adolesc Med, 158(8), 753-9, 2004.

Cooper, William O, Hickson, Gerald B, Ray, Wayne A. Prescriptions for contraindicated category X drugs in pregnancy among women enrolled in TennCare. Paediatr Perinat Epidemiol, 18(2), 106-11, 2004.

Valet, Robert S, Kutny, Diane F, Hickson, Gerald B, Cooper, William O. Family reports of care denials for children enrolled in TennCare. Pediatrics, 114(1), e37-42, 2004.

Cooper, William O, Boyce, Thomas G, Wright, Peter F, Griffin, Marie R. Do childhood vaccines have non-specific effects on mortality. Bull World Health Organ, 81(11), 821-6, 2003. PMCID:2572354

Cooper, William O, Lutenbacher, Melanie, Faccia, Kate, Hepworth, Joseph T. Planning of youth violence-prevention programs: development of a guiding measure. Public Health Nurs, 20(6), 432-9, 2003.

Porter, Christopher C, Poehling, Katherine A, Hamilton, Rodney, Frangoul, Haydar, Cooper, William O. Influenza immunization practices among pediatric oncologists.. J Pediatr Hematol Oncol, 25(2), 134-8, 2003.

Sox, CM, Cooper, WO, Koepsell, TD, DiGiuseppe, DL, Christakis, DA. Provision of pneumococcal prophylaxis for publicly insured children with sickle cell disease. JAMA, 290(8), 1057-61, 2003.

Cooper, W O, Kuhlthau, K. Evaluating medicaid managed care programs for children.. Ambul Pediatr, 1(2), 112-6, 2002.

Cooper, William O, Griffin, Marie R, Arbogast, Patrick, Hickson, Gerald B, Gautam, Shiva, Ray, Wayne A. Very early exposure to erythromycin and infantile hypertrophic pyloric stenosis.. Arch Pediatr Adolesc Med, 156(7), 647-50, 2002.

Cooper, William O, Ray, Wayne A, Griffin, Marie R. Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis.. Obstet Gynecol, 100(1), 101-6, 2002.

Cooper, William O, Staffa, Judy A, Renfrew, J William, Graham, David J, Ray, Wayne A. Oral corticosteroid use among children in TennCare.. Ambul Pediatr, 2(5), 375-81, 2002.

Lutenbacher, Melanie, Cooper, William O, Faccia, Kathleen. Planning youth violence prevention efforts: decision-making across community sectors.. J Adolesc Health, 30(5), 346-54, 2002.

Cooper, W O, Hickson, G B. Corticosteroid prescription filling for children covered by Medicaid following an emergency department visit or a hospitalization for asthma.. Arch Pediatr Adolesc Med, 155(10), 1111-5, 2001.

Cooper, W O, Lutenbacher, M, Faccia, K. Components of effective youth violence prevention programs for 7- to 14-year-olds.. Arch Pediatr Adolesc Med, 154(11), 1134-9, 2000.

Tamura, Y, Welch, D C, Zic, J A, Cooper, W O, Stein, S M, Hummell, D S. Scurvy presenting as painful gait with bruising in a young boy.. Arch Pediatr Adolesc Med, 154(7), 732-5, 2000.

Cooper, W O, Hickson, G B, Gray, C L, Ray, W A. Changes in continuity of enrollment among high-risk children following implementation of TennCare.. Arch Pediatr Adolesc Med, 153(11), 1145-9, 1999.

Cooper, W O, Hickson, G B, Mitchel, E F, Edwards, K M, Thapa, P B, Ray, W A. Early childhood mortality from community-acquired infections.. Am J Epidemiol, 150(5), 517-27, 1999.

Cooper, W O, Hickson, G B, Mitchel, E F, Ray, W A. Comparison of perinatal outcomes among TennCare managed care organizations.. Pediatrics, 104(3 Pt 1), 525-9, 1999.

Cooper, W O, Daniels, S R, Loggie, J M. Prevalence and correlates of blood pressure elevation in children with Guillain-Barr?? syndrome.. Clin Pediatr (Phila), 37(10), 621-4, 1998.

Hickson, G B, Cooper, W O, Campbell, P W, Altemeier, W A. Effects of pediatrician characteristics on management decisions in simulated cases involving apparent life-threatening events.. Arch Pediatr Adolesc Med, 152(4), 383-7, 1998.

Cooper, W O, Federspiel, C F, Griffin, M R, Hickson, G B. New use of anticonvulsant medications among children enrolled in the Tennessee Medicaid Program.. Arch Pediatr Adolesc Med, 151(12), 1242-6, 1997.

Cooper, W O, Kotagal, U R, Atherton, H D, Lippert, C A, Bragg, E, Donovan, E F, Perlstein, P H. Use of health care services by inner-city infants in an early discharge program.. Pediatrics, 98(4 Pt 1), 686-91, 1996.

Cooper, W O, Atherton, H D, Kahana, M, Kotagal, U R. Increased incidence of severe breastfeeding malnutrition and hypernatremia in a metropolitan area.. Pediatrics, 96(5 Pt 1), 957-60, 1995.

Cooper, W O, Fava, R A, Gates, C A, Cremer, M A, Townes, A S. Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-beta.. Clin Exp Immunol, 89(2), 244-50, 1992. PMCID:1554423


Postdoctoral Position Available
No

Postdoctoral Position Details
N/A

Updated Date
10/22/2013



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