Vanderbilt University School of Medicine

Kallianpur, Asha , M.D., M.P.H.

Lab Url: N/A

Phone Number: 6-8316

Email Address:asha.kallianpur@vanderbilt.edu

Kallianpur, Asha's picture

Office Address   Mailing Address

Institute for Medicine & Public Health, 2525 West End Avenue, Sixth Floor

Institute for Medicine & Public Health, Vanderbilt Epidemiology Center Vanderbilt University School of Medicine 37203-1738


Research Keywords
iron metabolism, hemochromatosis, genetic polymorphism, oxidative injury, genetic epidemiology, genomics, cancer risk and survival, chronic disease complications, HIV/AIDS, peripheral neuropathy, lipoatrophy, antiretroviral toxicity

Research Specialty
Iron-related genetic epidemiology of cancer risk, cancer survival, and chronic disease complications

Research Description
Dr. Asha Kallianpur is a physician-scientist and epidemiologist on the faculty of the Department of Medicine and Institute for Medicine & Public Health at Vanderbilt University. She is trained in Internal Medicine and Hematology, and her expertise includes: genetic disorders of iron metabolism such as hereditary hemochromatosis, oxidative injury, and the impact of variation in iron transport on chronic diseases and cancer. Her research team actively investigates the role of nuclear and mitochondrial genomic variation, including variation in iron transport, on breast and endometrial cancer etiology, cancer survival, and on chronic disease complications. With collaborators in Hematology, Infectious Diseases, Neurology, and Neuropathology, Dr. Kallianpur has studied the role of iron transport in chemotherapy toxicities and in antiretroviral drug-associated complications such as neuropathy and lipoatrophy, major problems for patients with cancer and HIV/AIDS, respectively, worldwide. The consistent theme of her iron-related translational work has been to develop the evidence base for interventions to improve clinical outcomes for patients with, or at risk for, cancer and other chronic conditions. Her ultimate goal is to translate accumulated knowledge about the relative risks and benefits of dietary and supplemental iron, into low-cost interventions for primary and secondary disease prevention.

Clinical Interests
Impact of iron deficiency and iron overload the clinical course of chronic diseases, benign hematology

Publications
Kallianpur AR, Poehling KA, Dittus RS. In: Saint S, Drazen J, and Solomon C (eds). High Time for Action. New England Journal of Medicine Clinical Problem-Solving. McGraw-Hill, New York, copyright 2006, , , .

Canter, JA, Robbins, GK, Selph, D, Clifford, DB, Kallianpur, AR, Shafer, R, Levy, S, Murdock, DG, Ritchie, MD, Haas, DW, Hulgan, T.. African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy. J Infect Dis, 201(11), 1703-7, 2010.

Dorjgochoo T, Gu K, Kallianpur AR, Zheng Y, Chen Z et al. Soy intake in association with menopausal symptoms during the first 6 and 36 months after breast cancer diagnosis. . Breast Cancer Res Treat (in press), , , 2010.

Dorjgochoo, T, Kallianpur, A, Zheng, Y, Gu, K, Chen, Z, Zheng, W, Lu, W, Shu, XO. Impact of menopausal symptoms on quality of life 6 months after systemic breast cancer treatment: results from the Shanghai Breast Cancer Survival Study. Breast Cancer Res Treat, 119(3), 725-35, 2010. PMCID:2731694

Kallianpur, AR, Lee, SA, Xu, WH, Zheng, W, Gao, YT, Cai, H, Ruan, ZX, Xiang, YB, Shu, XO. Dietary iron intake and risk of endometrial cancer: a population-based case-control study in Shanghai, China. Nutr Cancer, 62(1), 40-50, 2010.

Dorjgochoo, T, Gu, K, Kallianpur, A, Zheng, Y, Zheng, W, Chen, Z, Lu, W, Shu, XO. Menopausal symptoms among breast cancer patients 6 months after diagnosis: a report from the Shanghai Breast Cancer Survival Study. Menopause, 16(6), 1205-12, 2009. PMCID:2731694

Kallianpur, AR, Hulgan, T. Pharmacogenetics of nucleoside reverse-transcriptase inhibitor-associated peripheral neuropathy. Pharmacogenomics, 10(4), 623-37, 2009. PMCID:2706211

Murff, HJ, Shu, XO, Li, H, Dai, Q, Kallianpur, A, Yang, G, Cai, H, Wen, W, Gao, YT, Zheng, W. A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese women. Cancer Epidemiol Biomarkers Prev, 18(8), 2283-91, 2009. PMCID:2731694

Canter, JA, Haas, DW, Kallianpur, AR, Ritchie, MD, Robbins, GK, Shafer, RW, Clifford, DB, Murdock, DG, Hulgan, T. The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy. Pharmacogenomics J, 8(1), 71-7, 2008. PMCID:2615483

Dorjgochoo, T, Kallianpur, A, Gao, YT, Cai, H, Yang, G, Li, H, Zheng, W, Shu, XO. Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women''s Health Study. Menopause, 15(5), 924-33, 2008. PMCID:2615483

Hulgan, T, Tebas, P, Canter, JA, Mulligan, K, Haas, DW, Dub??, M, Grinspoon, S, Robbins, GK, Motsinger, AA, Kallianpur, AR, , . Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy. J Infect Dis, 197(6), 858-66, 2008. PMCID:2615483

Kallianpur, AR, Lee, SA, Gao, YT, Lu, W, Zheng, Y, Ruan, ZX, Dai, Q, Gu, K, Shu, XO, Zheng, W. Dietary animal-derived iron and fat intake and breast cancer risk in the Shanghai Breast Cancer Study. Breast Cancer Res Treat, 107(1), 123-32, 2008. PMCID:2615483

Lee, SA, Kallianpur, A, Xiang, YB, Wen, W, Cai, Q, Liu, D, Fazio, S, Linton, MF, Zheng, W, Shu, XO. Intra-individual variation of plasma adipokine levels and utility of single measurement of these biomarkers in population-based studies. Cancer Epidemiol Biomarkers Prev, 16(11), 2464-70, 2007. PMCID:2615483

Canter JA, Kallianpur AR, Parl FF, Millikan RC.. Response to Mims et al regarding "Mitochondrial DNA G10398A Polymorphism and Invasive Breast Cancer in African-American Women". Cancer Res, (66), 1880-1, 2006.

Canter, JA, Kallianpur, AR, Fowke, JH. Re: North American white mitochondrial haplogroups in prostate and renal cancer. J Urol, 176(5), 2308-9; author reply 2309, 2006. PMCID:2615483

Kallianpur, AR, Hulgan, T, Canter, JA, Ritchie, MD, Haines, JL, Robbins, GK, Shafer, RW, Clifford, DB, Haas, DW. Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy. AIDS, 20(11), 1503-13, 2006.

Pimanda, JE, Silberstein, L, Dominici, M, Dekel, B, Bowen, M, Oldham, S, Kallianpur, A, Brandt, SJ, Tannahill, D, G??ttgens, B, Green, AR. Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells. Mol Cell Biol, 26(7), 2615-25, 2006. PMCID:1430329

Canter, JA, Kallianpur, AR, Parl, FF, Millikan, RC. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res, 65(17), 8028-33, 2005.

Hulgan, T, Haas, DW, Haines, JL, Ritchie, MD, Robbins, GK, Shafer, RW, Clifford, DB, Kallianpur, AR, Summar, M, Canter, JA. Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. AIDS, 19(13), 1341-9, 2005.

Kallianpur, AR. Iron and oxidative injury-- a commentary on "Fatty acid-mediated iron translocation: a synergistic mechanism of oxidative injury" by D. Yao et al. Free Radic Biol Med, 39(10), 1305-9, 2005.

Kallianpur, AR. Genomic screening and complications of hematopoietic stem cell transplantation: has the time come. Bone Marrow Transplant, 35(1), 1-16, 2005.

Kallianpur, AR, Hall, LD, Yadav, M, Byrne, DW, Speroff, T, Dittus, RS, Haines, JL, Christman, BW, Summar, ML. The hemochromatosis C282Y allele: a risk factor for hepatic veno-occlusive disease after hematopoietic stem cell transplantation. Bone Marrow Transplant, 35(12), 1155-64, 2005.

Kallianpur, AR, Hall, LD, Yadav, M, Christman, BW, Dittus, RS, Haines, JL, Parl, FF, Summar, ML. Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer. Cancer Epidemiol Biomarkers Prev, 13(2), 205-12, 2004.

Summar, ML, Hall, L, Christman, B, Barr, F, Smith, H, Kallianpur, A, Brown, N, Yadav, M, Willis, A, Eeds, A, Cermak, E, Summar, S, Wilson, A, Arvin, M, Putnam, A, Wills, M, Cunningham, G. Environmentally determined genetic expression: clinical correlates with molecular variants of carbamyl phosphate synthetase I. Mol Genet Metab, 81 Suppl 1, S12-9, 2004.

Kallianpur, AR. Medical consensus and informed consent: the patient needs more time. Lancet, 362(9400), 2011, 2003.

Kallianpur, AR, Poehling, KA, Dittus, RS. Clinical problem-solving. High time for action. N Engl J Med, 344(1), 48-51, 2001.

Luther, JM, Lakey, DL, Larson, RS, Kallianpur, AR, D''Agata, E, Cousar, JB, Haas, DW. Utility of bone marrow biopsy for rapid diagnosis of febrile illnesses in patients with human immunodeficiency virus infection. South Med J, 93(7), 692-7, 2000.

Stein, RS, Greer, JP, Goodman, S, Kallianpur, A, Ahmed, MS, Wolff, SN. High-dose therapy with autologous or allogeneic transplantation as salvage therapy for small cleaved cell lymphoma of follicular center cell origin. Bone Marrow Transplant, 23(3), 227-33, 1999.

Kallianpur, AR, Jordan, JE, Brandt, SJ. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood, 83(5), 1200-8, 1994.

Kallianpur, A, Fleet, WF, Morgan, HJ. Hypokalemia and weight loss in a young woman. J Tenn Med Assoc, 83(9), 464-5, 1990.

Kallianpur, AR, Carstens, PH, Liotta, LA, Frey, KP, Siegal, GP. Immunoreactivity in malignant mesotheliomas with antibodies to basement membrane components and their receptors. Mod Pathol, 3(1), 11-8, 1990.


Postdoctoral Position Available
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Postdoctoral Position Details
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Updated Date
08/05/2010



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