Vanderbilt University School of Medicine

Casagrande, Vivien A. , Ph.D.
Professor of Cell and Developmental Biology
Professor of Psychology
Professor of Ophthalmology and Visual Sciences

Lab Url: http://www.psy.vanderbilt.edu/faculty/Casagrande/CasagrandeLab/index.htm

Phone Number: (615) 343-4538

Email Address:vivien.casagrande@vanderbilt.edu

Casagrande, Vivien's picture

Office Address   Mailing Address

T-2302 Medical Center North

U-3218 MCN (Learned Labs) 37232-8240


Research Keywords
visual system, brain development, morphology, electrophysiology, imaging, immunocytochemistry, neuroscience, behavior, vision,Neuroscience,Physiology,Vision

Research Description
The overall goal of this research is to understand how the visual thalamus and cortex interact to construct our perceptual world.

The first project explores the unconventional proposal that the primary sensory information received by the visual cortex from the visual thalamus [e.g., the lateral geniculate nucleus (LGN)] is not purely visual but rather visual information, primed by inputs from other sensory modalities. In this project, we hypothesize that the primate brain achieves fast and accurate decision-making in part due to its ability to focus, right from the beginning, on relevant aspects of inputs from all sense organs without appreciating all the details presented by each sense organ. Our specific hypothesis is that auditory and visual information are combined in a task dependent manner in the visual thalamus before this message is processed in cortex.

In a second project, we test the hypothesis that all thalamic nuclei contain some cell groups that act as drivers (send the main message) and some that act as modulators for multiple cortical areas, thus mediating the generation of an array of diverse cortical functions. The thalamus is not simply a passive relay to cortex. Instead, just as primary visual cortex (V1) depends on LGN, the secondary visual area (V2) and the middle temporal visual area (MT) depend on a combination of dedicated pathways through the thalamus (e.g., pulvinar) and direct feedforward connections from V1.This arrangement allows new properties to emerge at both the thalamic and cortical levels through dynamic loops.

A third project focuses on communication between cells in different areas of visual cortex and examines how visual messages are coded and transmitted from lower to higher visual areas and what the role of feedback is in this process.

We use a variety of electrophysiological, anatomical, and imaging approaches to address these questions including single unit and multielectrode recording in both anesthetized and awake behaving primates, light, electron microscopic and confocal examination of cells and circuits, optical imaging of intrinsic signals and pharmacological manipulation. Our laboratory also has had a long standing interest in the evolution of the visual system. Therefore, we continue to use a comparative approach to examine for similarities and differences in the organization of the visual system in a variety of primate species.

Publications
Li, K, Patel, J, Purushothaman, G, Marion, RT, Casagrande, VA. Retinotopic maps in the pulvinar of bush baby (Otolemur garnettii). J Comp Neurol, 521(15), 3432-50, 2013.

Marion, R, Li, K, Purushothaman, G, Jiang, Y, Casagrande, VA. Morphological and neurochemical comparisons between pulvinar and V1 projections to V2. J Comp Neurol, 521(4), 813-32, 2013.

Purushothaman, G, Casagrande, VA. A Generalized ideal observer model for decoding sensory neural responses. Front Psychol, 4, 617, 2013.

Fan, RH, Baldwin, MK, Jermakowicz, WJ, Casagrande, VA, Kaas, JH, Roe, AW. Intrinsic signal optical imaging evidence for dorsal V3 in the prosimian galago (Otolemur garnettii). J Comp Neurol, (520), 4254-4274, 2012.

Purushothaman, G, Marion, R, Li, K, Casagrande, VA. Gating and control of primary visual cortex by pulvinar. Nat Neurosci, (15), 905-912, 2012.

Casagrande, V.A. and Ichida, J.M.. Processing in the Lateral Geniculate Nucleus (LGN). Adlera??s Physiology of the Eye, 11th edition (A. Alm, P.L. Kaufman, (lead) L.A. Levin, S.F.E. Nilsson, J. Ver Hoeve and S.M. Wu, eds) Mosby, Elsevier, , 574-585, 2011.

Casagrande, V.A. and Marion, R.T.. Processing in the Primary Visual Cortex. Adlera??s Physiology of the Eye, 11th edition (A. Alm, P.L. Kaufman, (lead) L.A. Levin, S.F.E. Nilsson, J. Ver Hoeve and S.M. Wu, eds) Mosby, Elsevier, , 586-598, 2011.

Casagrande, V.A. and Purushothaman, G. , Modularity. Encyclopedia of Perception, Sage Publications, E.B. Goldstein, Ed., 561-566, 2009.

Jermakowicz, WJ, Chen, X, Khaytin, I, Bonds, AB, Casagrande, VA. Relationship between spontaneous and evoked spike-time correlations in primate visual cortex. J Neurophysiol, 101(5), 2279-89, 2009. PMCID:2681437

Purushothaman, G, Khaytin, I, Casagrande, VA. Quantification of optical images of cortical responses for inferring functional maps. J Neurophysiol, 101(5), 2708-24, 2009. PMCID:2681427

Boyd, J.D., I. Khaytin, and V. A. Casagrande. Comparative Evolutionary Aspects across Orders. Encyclopedia of Neuroscience (A. Butler, ed.), Springer Berlin Heidelberg, , 1448-1455, 2008.

Casagrande, V.A., I. Khaytin, and Boyd, J.. Evolution of the Visual System: Mammals-Color Vision and the Function of Parallel Visual Pathways in Primates. in Primates. In Encyclopedia of Neuroscience (A. Butler, ed), Springer Berlin Heidelberg, , 1472-1475, 2008.

Khaytin,I, Xin Chen, D.W. Royal, O. Ruiz, W.J. Jermakowicz, R.M. Siegel and Vivien A. Casagrande. Functional organization of temporal frequency selectivity in primate visual cortex. Cerebral Cortex, 18, 1828-1842, 2008.

Casagrande, V.A., X. Chen and W. J. Jermakowicz What language is spoken here? Conversations between neurons in primate visual cortex. Proceedings of the 1st International Conference on Cognitive Neurodynamics (ICCN-07) and 3rd International conference on Physiological Biophysics. Cognitive Neurodynamics (ICCN 2007 proceedings

Casagrande, V.A., Khaytin, I., and Boyd, J.. The evolution of parallel visual pathways in the brains of primates. Evolution of the Nervous System (T.M. Preuss and J. Kaas, eds.), 4, 87-108, 2007.

Casagrande, VA, Yazar, F, Jones, KD, Ding, Y. The morphology of the koniocellular axon pathway in the macaque monkey. Cereb Cortex, 17(10), 2334-45, 2007.

Jermakowicz, WJ, Casagrande, VA. Neural networks a century after Cajal. Brain. Res. Rev., (55), 264-284, 2007. PMCID:2101763

Xu, X, Anderson, TJ, Casagrande, VA. How do functional maps in primary visual cortex vary with eccentricity. J Comp Neurol, 501(5), 741-55, 2007.

Elston, G.N., R. Benavides-Piccione, A. Elston, B. Zietsch, J. DeFelipe, P. Manger, V. Casagrande and J. Kaas. Specializations of the granular prefrontal cortex of primates: implications for cognitive processing. Anatomical Record Part A, 288A(1), 26-35, 2006.

Royal, DW, S?!ry, G, Schall, JD, Casagrande, VA. Correlates of motor planning and postsaccadic fixation in the macaque monkey lateral geniculate nucleus. Exp Brain Res, 168(1-2), 62-75, 2006.

Ruiz, O, Royal, DW, Sary, G, Chen, X, Schall, JD, Casagrande, VA. Low-threshold Ca2+-associated bursts are rare Events in the LGN of the awake behaving monkey. J Neurophysiol, 95(6), 3401-13, 2006.

Xu, X, Collins, CE, Khaytin, I, Kaas, JH, Casagrande, VA. Unequal representation of cardinal vs. oblique orientations in the middle temporal visual area. Proc Natl Acad Sci U S A, 103(46), 17490-5, 2006. PMCID:1859956

Casagrande, V.A., R. Guillery, and S. Sherman, eds. Cortical function: a view from the thalamus (book). In Progress in Brain Research vol. 149, Amsterdam: Elsevier, pp 11-31.

Casagrande, V.A., Royal, D.W., Sa??, Gy. Extraretinal inputs and feedback mechanisms to the lateral geniculate nucleus (LGN). In The Primate Visual System: A Comparative Approach (Jan Kremers, ed.) Hoboken, New Jersey: John Wiley and Sons, pp. 191-206.

Casagrande, V. A., Gy. Sary, D. Royal, and O. Rui. On the impact of attention and motor planning on the lateral geniculate nucleus. In Progress in Brain Research, vol. 149: Cortical Function: A View from the Thalamus (V. A. Casagrande, S. M. Sherman and R. W. Guillery, eds), Amsterdam: Elsevier, 11-29, 2005.

Casagrande, VA, S?!ry, G, Royal, D, Ruiz, O. On the impact of attention and motor planning on the lateral geniculate nucleus. Prog Brain Res, 149, 11-29, 2005. PMCID:1859956

Collins CE, Xu X, Khaytin I, Kaskan PM, Casagrande VA, Kaas JH. Optical imaging of visually evoked responses in the middle temporal area after deactivation of primary visual cortex in adult primates. Proceedings of the National Academy of Sciences USA, 102(15), 5594-5599, 2005.

Collins, CE, Xu, X, Khaytin, I, Kaskan, PM, Casagrande, VA, Kaas, JH. Optical imaging of visually evoked responses in the middle temporal area after deactivation of primary visual cortex in adult primates. Proc Natl Acad Sci U S A, 102(15), 5594-9, 2005. PMCID:556248

Elston GN, Elston E, Casagrande V, Kaas JH. Areal specialization of pyramidal cell structure in the visual cortex of the tree shrew: a new twist revealed in the evolution of cortical circuitry. Experimental Brain Research, 163, 13-20, 2005.

Elston, GN, Elston, A, Casagrande, V, Kaas, JH. Pyramidal neurons of granular prefrontal cortex of the galago: complexity in evolution of the psychic cell in primates. Anat Rec A Discov Mol Cell Evol Biol, 285(1), 610-8, 2005.

Elston, GN, Elston, A, Kaas, JH, Casagrande, V. Regional specialization in pyramidal cell structure in the visual cortex of the galago: an intracellular injection study of striate and extrastriate areas with comparative notes on new world and old world monkeys. Brain Behav Evol, 66(1), 10-21, 2005.

Xu, X, Bosking, WH, White, LE, Fitpatrick, D, Casagrande, VA. Functional Organization of Visual Cortex in the Prosimian Bush Baby Revealed by Optical Imaging of Intrinsic Signals. J Neurophysiol, , , 2005.

Wiencken-Barger AE, Mavity-Hudson J, Bartsch U, Schachner M, and Casagrande VA. The role of L1 in axon pathfinding and fasciculation. Cerebral Cortex, 14(2), 121-31, 2004.

Xu X, Bosking W, S?!ry Gy, Stefansic J, Shima D, and Casagrande V. Functional organization of visual cortex in the owl monkey. Journal of Neuroscience, 28(24), 6237-47, 2004.

Xu X, Collins CE, Kaskan PM, Khaytin I, Kaas JH, and Casagrande VA. Optical imaging of visually evoked responses in prosimian primates reveals conserved features of the middle temporal visual area. Proceedings of the National Academy of Sciences USA, 101(8), 2566-71, 2004. PMCID:356990

Casagrande, VA, Xu X, and S?!ry G. Static and dynamic views of visual cortical organization, pp. 389-408 in Rakic P, Azmitia E, deFelipe J, Ribak C and Jones E, eds., in Changing Views of Cajal's Neuron. In Progress in Brain Research, Vol. 136 (Oxford, UK: Elsevier Science B.V.), 2003.

Casagrande, V. A. & Royal, D. . Parallel visual pathways in a dynamic system. . Primate Vision (J. H. Kaas and C. E. Collins, eds.) Boca Raton, FL: CRC Press, , 1-28, 2003.

Casagrande, V. A. & Xu, X.. Parallel visual pathways: a comparative perspective. . The Visual Neurosciences (L. Chalupa and John S. Werner, eds.), , 494-506, 2003.

Emeric, E., Xu, X., Mavity-Hudson, J., Gallucci, M., Thomas, A., Barahimi, B., Shima, D., Stefansic, J., Bonds, A. B. & Casagrande, V. A.. Visuotopic organization of bush baby primary visual cortex (V1) revealed by optical imaging. Vision Sciences Society. Journal of Vision, 3(9), 376a, 2003.

Ichida, J. M.,Royal, D., Sary G., Schall, J., & Casagrande, V. A. . Are there significant onset latency differences between LGN cells that carry S cone signals compared to those that carry M or L cone signals? . Washington, DC: Society for Neuroscience, 2003. Online., , , 2003.

Joos KM, Mawn LA, Shen JH, and Casagrande VA. Chronic and acute analysis of optic nerve sheath fenestration with the free electron laser in monkeys. Lasers in Surgery and Medicine, 32(1), 32-41, 2003.

Joos, K., Mawn, L., Shen, J. & Casagrande, V. A.. Chronic and acute analysis of optic nerve sheath fenestration with the free electron laser in monkeys. . Lasers in Surgery and Medicine , 32, 32-41, 2003.

Royal, D. W.,Sary, G., Schall, J., & Casagrande, V. A. . Are spike bursts and pseudo- bursts in the lateral geniculate nucleus (LGN) related to behavioral events?. Washington, DC: Society for Neuroscience, 2003. Online., , , 2003.

Royal, D., Sary, G., Schall, J. & Casagrande, V. A. . Is there a relationship between spike bursts in the lateral geniculate nucleus (LGN) and behavioral events? . Vision Sciences Society,Journal of Vision, 3(9), 366a, 2003.

Shostak Y, Ding Y, and Casagrande VA. Neurochemical comparison of synaptic arrangements of parvocellular, magnocellular, and koniocellular geniculate pathways in owl monkey (Aotus trivirgatus) visual cortex. Journal of Comparative Neurology, 456(1), 12-28, 2003.

Thomas, A., Gallucci, M., Xu, X., Allison, J., Stefansic, J., Shima, D., Casagrande, V. & Bonds, A. B. (2003).. Compound stimuli promote architectural reorganization in cat striate cortex.. Vision Sciences Society, Journal of Vision, 3(9), 379a, 2003.

Xu X, Bonds AB, and Casagrande VA. Modeling receptive-field structure of koniocellular, magnocellular, and parvocellular LGN cells in the owl monkey (Aotus trivigatus). Visual Neuroscience, 19(6), 703-11, 2003.

Xu, X., Boyd, J., Gallucci, M., Emeric, E., Barahimi, B., Stefansic, J., Shima, D., Melzer, P., Allison, J., Bonds, A. B. & Casagrande, V. A. . Spatial frequency preference maps of primatevisual cortex revealed by optical imaging of intrinsic signals. . Vision Sciences Society, Journal of Vision, 3(9), 107a, 2003.

Casagrande VA, Xu X, and S?!ry Gy. Static and dynamic views of visual cortical organization. Progress in Brain Research, 136, 389-408, 2002.

Casagrande, V. A., & Ichida, J. M.. The lateral geniculate nucleus. . F. H. Adler (Ed.), Physiology of the eye, , 655-668, 2002.

Casagrande, V. A., & Ichida, J. M. . The visual cortex.. F. H. Adler (Ed.), Physiology of the eye, , 669-685, 2002.

Ichida JM and Casagrande VA. Organization of the feedback pathway from striate cortex (V1) to the lateral geniculate nucleus (LGN) in the owl monkey (Aotus trivirgatus). Journal of Comparative Neurology, 454(3), 272-83, 2002.

Joos, K. M., Shen, J. H., Robinson, R. D., & Casagrande, V. A. . Free electron laser-treated tisseel aids closure of trabeculectomy leaks. Investigative Ophthalmology & Visual Science.. Investigative Ophthalmology & Visual Science., , , 2002.

Lyon DC, Xu X, Casagrande VA, Stefansic JD, Shima D, and Kaas JH. Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys. Proceedings of the National Academy of Sciences USA, 99(24), 15735-42, 2002. PMCID:137785

Shostak Y, Ding Y, Mavity-Hudson J, and Casagrande VA. Cortical synaptic arrangements of the third visual pathway in three primate species: Macaca mulatta, Saimiri sciureus, and Aotus trivirgatus. Journal of Neuroscience, 22(7), 2885-93, 2002.

Shostak, Y., Ding, Y., & Casagrande, V. A. (. Neurochemical comparison of synaptic circuitry of koniocellular (K), magnocellular (M) and parvocellular (P) geniculate pathways in owl monkey (Aotus trivirgatus) visual cortex. Journal of Comparative Neurology, 454, 168-184.. Journal of Comparative Neurology, 454, 168-184, 2002.

Wiencken-Barger, A. E., & Casagrande, V. A.. Visual system development and neural activity.. V. S. Ramachandran (Ed.), Encyclopedia of the human brain, , 791-804, 2002.

Xu X, Ichida J, Shostak Y, Bonds AB, and Casagrande VA. Are primate lateral geniculate nucleus (LGN) cells really sensitive to orientation or direction. Visual Neuroscience, 19(1), 97-108, 2002.

Xu, X., Bosking, W., Sary, G., Jones, M., Royal, D., Stefansic, J., Shima, D., Fitzpatrick, D., & Casagrande, V. A.. The functional of organization of orientation maps in owl monkey V1 and V2 revealed by optical imaging of intrinsic signals. Visual Science Society, B1, 100.. Visual Science Society, B1, 100, 2002.

Xu, X, Ichida, JM, Allison, JD, Boyd, JD, Bonds, AB, Casagrande, VA. A comparison of koniocellular, magnocellular and parvocellular receptive field properties in the lateral geniculate nucleus of the owl monkey (Aotus trivirgatus). J Physiol, 531(Pt 1), 203-18, 2001. PMCID:2278453

Casagrande VA and Wiencken-Barger AE, Developmental plasticity in the mammalian visual system, pp. 1-48 in Kaas JH, ed., The Mutable Brain: Dynamic and Plastic Features of the Developing and Mature Brain (Amsterdam, Netherlands: Harwood), 2000

Allison JD, Melzer P, Ding Y, Bonds AB, and Casagrande VA. Differential contributions of magnocellular and parvocellular pathways to the contrast response of neurons in bush baby primary visual cortex (V1). Visual Neuroscience, 17(1), 71-6, 2000.

Boyd JD, Mavity-Hudson JA, and Casagrande VA. The connections of layer 4 subdivisions in the primary visual cortex (V1) of the owl monkey. Cerebral Cortex, 10(7), 644-62, 2000.

Ichida JM, Rosa MG, Casagrande VA. Does the visual system of the flying fox resemble that of primates? The distribution of calcium-binding proteins in the primary visual pathway of Pteropus poliocephalus. Journal of Comparative Neurology, 417(1), 73-87, 2000.

Joos KM, Shen JH, Shetlar DJ, and Casagrande VA. Optic nerve sheath fenestration with a novel wavelength produced by the free electron laser (FEL). Lasers in Surgery and Medicine, 27(3), 191-205, 2000.

Wiencken AE and Casagrande VA. The distribution of NADPH diaphorase and nitric oxide synthetase (NOS) in relation to the functional compartments of areas V1 and V2 of primate visual cortex. Cerebral Cortex, 10(5), 499-511, 2000.

Boyd JD and Casagrande VA. Relationships between cytochrome oxidase (CO) blobs in primate primary visual cortex (V1) and the distribution of neurons projecting to the middle temporal area (MT). Journal of Comparative Neurology, 409(4), 573-91, 1999.

Casagrande VA. The mystery of the visual system K pathway. Journal of Physiology, 517(3), 630, 1999. PMCID:2269392

Wiencken AE and Casagrande VA. Endothelial nitric oxide synthetase (eNOS) in astrocytes: another source of nitric oxide in neocortex. Glia, 26(4), 280-90, 1999.

Casagrande VA. Review of The First Steps in Seeing by Rodieck RW, Sinauer Associates. Trends in Neurosciences, 22, 327-328, 1998.

Casagrande VA. The Cortical Discoverer Prize: Tamas F. Freund. Cerebral Cortex, 8(5), 478-9, 1998.

Casagrande VA. The Cortical Scholar Prize: Dun H. Ha and Frank A. Middleton. Cerebral Cortex, 8(5), 477-8, 1998.

Casagrande VA. The Cortical Explorer Award: Nelson Spruston. Cerebral Cortex, 8(5), 478, 1998.

Ding Y and Casagrande VA. Synaptic and neurochemical characterization of parallel pathways to the cytochrome oxidase blobs of primate visual cortex. Journal of Comparative Neurology, 391(4), 429-43, 1998.

Yamada, E. S., Marshak. D. W., Carlos, L., Silveira, L., & Casagrande, V. A. . Morphology of P and M retinal ganglion cells of the bush baby. Vision Research, 38, 3345-3352.. , 38, 3345-3352, 1998.

Yamada, E. S., Marshak. D. W., Carlos, L., Silveira, L., & Casagrande, V. A. . Morphology of P and M retinal ganglion cells of the bush baby. Vision Research, 38, 3345-3352.. , 38, 3345-3352, 1998.

Yamada, ES, Marshak, DW, Silveira, LC, Casagrande, VA. Morphology of P and M retinal ganglion cells of the bush baby. Vision Res, 38(21), 3345-52, 1998.

Ding Y and Casagrande VA. The distribution and morphology of LGN K pathway axons within the layers and CO blobs of owl monkey V1. Visual Neuroscience, 14(4), 691-704, 1997.

Rosa MG, Casagrande VA, Preuss T, Kaas JH. Visual field representation in striate and prestriate cortices of a prosimian primate (Galago garnetti). Journal of Neurophysiology, 77(6), 3193-217, 1997.

Casagrande VA and Wiencken AE, Prenatal development of axon outgrowth and connectivity, pp. 83-93 in Mize RR, Erzurumulu RS, eds., in Neural Development and Plasticity, vol. 108, Progress in Brain Research (New York: Elsevier), 1996

Allison JD, Kabara JF, Snider RK, Casagrande VA, Bonds AB. GABAB-receptor-mediated inhibition reduces the orientation selectivity of the sustained response of striate cortical neurons in cats. Visual Neuroscience, 13(3), 559-66, 1996.

Casagrande VA and Boyd JD. The neural architecture of binocular vision. Eye, 10 ( Pt 2), 153-60, 1996.

Casagrande VA and Wiencken AE. Prenatal development of axon outgrowth and connectivity. Progress in Brain Research, 108, 83-93, 1996.

Singleton CD and Casagrande VA. A reliable and sensitive method for fluorescent photoconversion. Journal of Neuroscience Methods, 64(1), 47-54, 1996.

Allison JD, Casagrande VA, and Bonds AB. The influence of input from the lower cortical layers on the orientation tuning of upper layer V1 cells in a primate. Visual Neuroscience, 12(2), 309-20, 1995.

Johnson JK and Casagrande VA. Distribution of calcium-binding proteins within the parallel visual pathways of a primate (Galago crassicaudatus). Journal of Comparative Neurology, 356(2), 238-60, 1995.

Casagrande VA, Kaas JH, The afferent, intrinsic, and efferent connections of primary visual cortex in primates, pp. 201-259 in Peters A and Rockland K, eds., Primary Visual Cortex of Primates, vol. 10, Cerebral Cortex (New York: Plenum), 1994

Casagrande VA, Shinkman PG, eds. Advances in Neural and Behavioral Development, vol. 4 (Norwood, NJ: Ablex), 1994

Casagrande VA. A third parallel visual pathway to primate area V1. Trends in Neuroscience, 17(7), 305-10, 1994.

Allison JD, Casagrande VA, Debruyn EJ, and Bonds AB. Contrast adaptation in striate cortical neurons of the nocturnal primate bush baby (Galago crassicaudatus). Visual Neuroscience, 10(6), 1129-39, 1993.

DeBruyn EJ, Casagrande VA, Beck PD, and Bonds AB. Visual resolution and sensitivity of single cells in the primary visual cortex (V1) of a nocturnal primate (bush baby): correlations with cortical layers and cytochrome oxidase patterns. Journal of Neurophysiology, 69(1), 3-18, 1993.

Irvin, GE, Casagrande, VA, Norton, TT. Center/surround relationships of magnocellular, parvocellular, and koniocellular relay cells in primate lateral geniculate nucleus. Vis Neurosci, 10(2), 363-73, 1993.

Johnson JK and Casagrande VA. Prenatal development of axon outgrowth and connectivity in the ferret visual system. Visual Neuroscience, 10(1), 117-30, 1993.

Lachica EA and Casagrande VA. The morphology of collicular and retinal axons ending on small relay (W-like) cells of the primate lateral geniculate nucleus. Visual Neuroscience, 10(3), 403-18, 1993.

Lachica EA, Beck PD, Casagrande VA. Intrinsic connections of layer III of striate cortex in squirrel monkey and bush baby: correlations with patterns of cytochrome oxidase. Journal of Comparative Neurology, 329(2), 163-87, 1993.

Lachica EA and Casagrande VA. Direct W-like geniculate projections to the cytochrome oxidase (CO) blobs in primate visual cortex: axon morphology. Journal of Comparative Neurology, 319(1), 141-58, 1992.

Lachica EA, Beck PD, and Casagrande VA. Parallel pathways in macaque monkey striate cortex: anatomically defined columns in layer III. Proceedings of the National Academy of Sciences USA, 89(8), 3566-70, 1992. PMCID:48909

Casagrande VA, Norton TT, The lateral geniculate nucleus: A review of its physiology and function, pp. 41-84, in Cronley-Dillon JR, ed., The Neural Basis of Visual Function, vol. 4, Vision and Visual Dysfunction (London: MacMillan), 1991

Lachica EA, Mavity-Hudson JA, and Casagrande VA. Morphological details of primate axons and dendrites revealed by extracellular injection of biocytin: an economic and reliable alternative to PHA-L. Brain Research, 564(1), 1-11, 1991.

Casagrande VA, Hutchins JB, Methods for analyzing neuronal connections in mammals, pp. 188-207 in Conn M, ed., Methods in Neurosciences, Vol. 3 (Orlando, FL: Academic), 1990.

Lachica EA, Casagrande VA, Methods for visualizing and analyzing individual axon arbors, pp. 230-244 in Conn M, ed., Methods in Neurosciences, Vol. 3 (Orlando, FL: Academic), 1990

Claps A and Casagrande VA. The distribution and morphology of corticogeniculate axons in ferrets. Brain Research, 530(1), 126-9, 1990.

Condo GJ and Casagrande VA. Organization of cytochrome oxidase staining in the visual cortex of nocturnal primates (Galago crassicaudatus and Galago senegalensis): I. Adult patterns. Journal of Comparative Neurology, 293(4), 632-45, 1990.

Florence SL and Casagrande VA.. Development of geniculocortical axon arbors in a primate. Visual Neuroscience, 5(3), 291-309, 1990.

Hutchins JB and Casagrande VA. Development of the lateral geniculate nucleus: interactions between retinal afferent, cytoarchitectonic, and glial cell process lamination in ferrets and tree shrews. Journal of Comparative Neurology, 298(1), 113-28, 1990.

Lachica EA, Crooks MW, and Casagrande VA. Effects of monocular deprivation on the morphology of retinogeniculate axon arbors in a primate. Journal of Comparative Neurology, 296(2), 303-23, 1990.

Hutchins JB and Casagrande VA. Vimentin: changes in distribution during brain development. Glia, 2(1), 55-66, 1989.

Nidoli, G, Macchi, A, Lazzati, M, Casagrande, V. [Lingual appliances: indirect application of lingual brackets. 2. Mondo Ortod, 14(2), 165-71, 1989.

Nidoli, G, Macchi, A, Lazzati, M, Casagrande, V. [Lingual appliances. Mondo Ortod, 14(1), 23-30, 1989.

Nidoli, G, Macchi, A, Lazzati, M, Casagrande, V. [Lingual appliances. 3. Mondo Ortod, 14(3), 335-41, 1989.

Casagrande VA and Condo GJ. Is binocular competition essential for layer formation in the lateral geniculate nucleus. Brain Behavior and Evolution, 31(4), 198-208, 1988.

Casagrande VA and Condo GJ. The effect of altered neuronal activity on the development of layers in the lateral geniculate nucleus. Journal of Neuroscience, 8(2), 395-416, 1988.

Hutchins JB and Casagrande VA. Glial cells develop a laminar pattern before neuronal cells in the lateral geniculate nucleus. Proceedings of National Academy of Sciences USA, 85(21), 8316-20, 1988. PMCID:282420

Hutchins JB and Casagrande VA. Development of acetylcholinesterase activity in the lateral geniculate nucleus. Journal of Comparative Neurology, 275(2), 241-53, 1988.

Lachica EA and Casagrande VA. Development of primate retinogeniculate axon arbors. Visual Neuroscience, 1(1), 103-23, 1988.

Norton, TT, Casagrande, VA, Irvin, GE, Sesma, MA, Petry, HM. Contrast-sensitivity functions of W-, X-, and Y-like relay cells in the lateral geniculate nucleus of bush baby, Galago crassicaudatus. J Neurophysiol, 59(6), 1639-56, 1988.

Bonds AB, Casagrande VA, Norton TT, and DeBruyn EJ. Visual resolution and sensitivity in a nocturnal primate (galago) measured with visual evoked potentials. Vision Research, 27(6), 845-57, 1987.

Condo GJ, Marvin SA, and Casagrande, VA. Postnatal development of geniculocortical projections in the tree shrew. Brain Research, 432(1), 148-52, 1987.

Florence SL and Casagrande VA. Organization of individual afferent axons in layer IV of striate cortex in a primate. Journal of Neuroscience, 7(12), 3850-68, 1987.

Lachica, EA, Condo, GJ, Casagrande, VA. Development of cytochrome oxidase staining in the retina and lateral geniculate nucleus: a possible correlate of ON- and OFF-center channel maturation. Brain Res, 431(2), 298-302, 1987.

Preda, GE, Castoldi, A, Boggio, E, Casagrande, V, Conconi, M, Azzi, R. [Follow-up of 2 cases of untreated cherubism. Dent Cadmos, 55(20), 75-9, 1987.

Florence, SL, Casagrande, VA. Changes in the distribution of geniculocortical projections following monocular deprivation in tree shrews. Brain Res, 374(1), 179-84, 1986.

Florence, SL, Conley, M, Casagrande, VA. Ocular dominance columns and retinal projections in New World spider monkeys (Ateles ater). J Comp Neurol, 243(2), 234-48, 1986.

Irvin, GE, Norton, TT, Sesma, MA, Casagrande, VA. W-like response properties of interlaminar zone cells in the lateral geniculate nucleus of a primate (Galago crassicaudatus). Brain Res, 362(2), 254-70, 1986.

Langston, A, Casagrande, VA, Fox, R. Spatial resolution of the Galago. Vision Res, 26(5), 791-6, 1986.

Brunso-Bechtold, JK, Casagrande, VA. Ultrastructure of the developing tree shrew lateral geniculate nucleus. Brain Res, 355(2), 310-4, 1985.

Brunso-Bechtold, JK, Casagrande, VA. Presence of retinogeniculate fibers is essential for initiating the formation of each interlaminar space in the lateral geniculate nucleus. Brain Res, 352(1), 123-6, 1985.

Conley, M, Birecree, E, Casagrande, VA. Neuronal classes and their relation to functional and laminar organization of the lateral geniculate nucleus: a Golgi study of the prosimian primate, Galago crassicaudatus. J Comp Neurol, 242(4), 561-83, 1985.

Conley, M, Lachica, EA, Casagrande, VA. Demonstration of ipsilateral retinocollicular projections in the tree shrew (Tupaia glis). Brain Res, 346(1), 181-5, 1985.

Holscher, MA, Sly, DL, Cousar, JB, Glick, AD, Casagrande, VA. Monocytic leukemia in a greater bushbaby (Galago crassicaudatus argentatus). Lab Anim Sci, 34(6), 619-20, 1984.

Petry, HM, Fox, R, Casagrande, VA. Spatial contrast sensitivity of the tree shrew. Vision Res, 24(9), 1037-42, 1984.

Sesma, MA, Casagrande, VA, Kaas, JH. Cortical connections of area 17 in tree shrews. J Comp Neurol, 230(3), 337-51, 1984.

Sesma, MA, Irvin, GE, Kuyk, TK, Norton, TT, Casagrande, VA. Effects of monocular deprivation on the lateral geniculate nucleus in a primate. Proc Natl Acad Sci U S A, 81(7), 2255-9, 1984. PMCID:345477

Brunso-Bechtold, JK, Florence, SL, Casagrande, VA. The role of retinogeniculate afferents in the development of connections between visual cortex and the dorsal lateral geniculate nucleus. Brain Res, 312(1), 33-9, 1983.

Florence, SL, Sesma, MA, Casagrande, VA. Morphology of geniculo-striate afferents in a prosimian primate. Brain Res, 270(1), 127-30, 1983.

Brunso-Bechtold, JK, Casagrande, VA. Early postnatal development of laminar characteristics in the dorsal lateral geniculate nucleus of the tree shrew. J Neurosci, 2(5), 589-97, 1982.

Norton, TT, Casagrande, VA. Laminar organization of receptive-field properties in lateral geniculate nucleus of bush baby (Galago crassicaudatus). J Neurophysiol, 47(4), 715-41, 1982.

Brunso-Bechtold, JK, Casagrande, VA. Effect of bilateral enucleation on the development of layers in the dorsal lateral geniculate nucleus. Neuroscience, 6(12), 2579-86, 1981.

DeBruyn, EJ, Casagrande, VA. Demonstration of ocular dominance columns in a New World primate by means of monocular deprivation. Brain Res, 207(2), 453-8, 1981.

Casagrande, VA, Joseph, R. Morphological effects of monocular deprivation and recovery on the dorsal lateral geniculate nucleus in galago. J Comp Neurol, 194(2), 413-26, 1980.

DeBruyn, EJ, Wise, VL, Casagrande, VA. The size and topographic arrangement of retinal ganglion cells in the galago. Vision Res, 20(4), 315-27, 1980.

Graham, J, Casagrande, VA. A light microscopic and electron microscopic study of the superficial layers of the superior colliculus of the tree shrew (Tupaia glis). J Comp Neurol, 191(1), 133-51, 1980.

Joseph, R, Casagrande, VA. Visual deficits and recovery following monocular lid closure in a prosimian primate. Behav Brain Res, 1(2), 165-86, 1980.

Haseltine, EC, DeBruyn, EJ, Casagrande, VA. Demonstration of ocular dominance columns in Nissl-stained sections of monkey visual cortex following enucleation. Brain Res, 176(1), 153-8, 1979.

Casagrande, VA, Guillery, RW, Harting, JK. Differential effects of monocular deprivation seen in different layers of the lateral geniculate nucleus. J Comp Neurol, 179(3), 469-85, 1978.

Harting, JK, Casagrande, VA, Weber, JT. The projection of the primate superior colliculus upon the dorsal lateral geniculate nucleus: autoradiographic demonstration of interlaminar distribution of tectogeniculate axons. Brain Res, 150(3), 593-9, 1978.

McKanna, JA, Casagrande, VA. Reduced lens development in lid-suture myopia. Exp Eye Res, 26(6), 715-23, 1978.

Guillery, RW, Casagrande, VA. Studies of the modifiability of the visual pathways in Midwestern Siamese cats. J Comp Neurol, 174(1), 15-46, 1977.

Norton, TT, Casagrande, VA, Sherman, SM. Loss of Y-cells in the lateral geniculate nucleus of monocularly deprived tree shrews. Science, 197(4305), 784-6, 1977.

Sherman, SM, Norton, TT, Casagrande, VA. Myopia in the lid-sutured tree shrew (Tupaia glis). Brain Res, 124(1), 154-7, 1977.

Weber, JT, Casagrande, VA, Harting, JK. Transneuronal transport of [3H]proline within the visual system of the grey squirrel. Brain Res, 129(2), 346-52, 1977.

Guillery, RW, Casagrande, VA. Adaptive synaptic connections formed in the visual pathways in response to congenitally aberrant inputs. Cold Spring Harb Symp Quant Biol, 40, 611-7, 1976.

Kaas, JH, Lin, CS, Casagrande, VA. The relay of ipsilateral and contralateral retinal input from the lateral geniculate nucleus to striate cortex in the owl monkey: a transneuronal transport study. Brain Res, 106(2), 371-8, 1976.

Raczkowski, D, Casagrande, VA, Diamond, IT. Visual neglect in the tree shrew after interruption of the descending projections of the deep superior colliculus. Exp Neurol, 50(1), 14-29, 1976.

Casagrande, VA. Dual function of the tectum in the tree shrew (Tupaia glis). Neurosci Res Program Bull, 13(2), 251-3, 1975.

Casagrande, VA, Harting, JK. Transneuronal transport of tritiated fucose and proline in the visual pathways of tree shrew Tupaia glis. Brain Res, 96(2), 367-72, 1975.

Sherman, SM, Norton, TT, Casagrande, VA. X- and Y-cells in the dorsal lateral geniculate nucleus of the tree shrew (Tupaia glis). Brain Res, 93(1), 152-7, 1975.

Casagrande, VA, Diamond, IT. Ablation study of the superior colliculus in the tree shrew (Tupaia glis). J Comp Neurol, 156(2), 207-37, 1974.

Guillery, RW, Casagrande, VA, Oberdorfer, MD. Congenitally abnormal vision in Siamese cats. Nature, 252(5480), 195-9, 1974.

Ware, CB, Diamond, IT, Casagrande, VA. Effects of ablating the striate cortex on a successive pattern discrimination:further study of the visual system in the tree shrew (Tupaia glis). Brain Behav Evol, 9(4), 264-79, 1974.

Casagrande, VA, Harting, JK, Hall, WC, Diamond, IT, Martin, GF. Superior colliculus of the tree shrew: a structural and functional subdivision into superficial and deep layers. Science, 177(47), 444-7, 1972.

Ware, CB, Casagrande, VA, Diamond, IT. Does the acuity of the tree shrew suffer from removal of striate cortex? A commentary on the paper by ward and Masterton. Brain Behav Evol, 5(1), 18-29, 1972.


Postdoctoral Position Available
No

Postdoctoral Position Details
N/A

Updated Date
11/12/2013



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