Vanderbilt University School of Medicine

Nanney, Lillian B. , Ph.D.
Professor of Plastic Surgery
Professor of Medical Education and Administration
Professor of Cell and Developmental Biology

Lab Url: N/A

Phone Number: 615-322-7265

Email Address:Lillian.Nanney@vanderbilt.edu

Nanney, Lillian's picture

Office Address   Mailing Address

S-2221 Medical Center North

S-2221 MCN Plastic Surgery Research Laboratory 37232-2631


Research Keywords
wound repair, regeneration, burns, chronic wounds, cutaneous biology, animal models of wound healing, immunohistochemistry, proteomics,Gene therapy,Proteomics,Receptor,Signal transduction,Stem cells

Research Description
The primary goal of the laboratory is to investigate cutaneous growth control mechanisms in the skin whether it be in wound healing settings where accelerated growth or regeneration is desired or whether it be in benign or neoplastic growth where growth inhibition is desired.

Our mechanistic wound healing studies are conducted primarily in porcine and mouse models but typically compared against the molecular events within human skin. We have expanded beyond our original focus of examining the role of ErbB receptors and related cytokines to a more global examination of the complex interplay of genes and proteins expressed in response to cutaneous injury and the subsequent events of wound repair. One goal is to elucidate the temporal sequence of human genes and proteins that are misregulated following injury and which lead to inflammatory perturbations and wound scarring and contracture. The ultimate goal is to discover pivotal molecules that can be either overexpressed or suppressed in the clinical quest to intervene and produce a more timely repair with a more regenerative and aesthetically pleasing outcome.

Dr. Nanney also serves as the Director of Vanderbilt's Instituional Immunohistochemistry Core. She directs a team that is always testing new antisera and developing successful immunostaining working protocols that become immediately available to Vanderbilt's research community. The core also provides routine embedding and histological services for human and animal tissues.

Dr. Nanney is the founding Director of the Academy for Excellence in Teaching that was recently established within the Medical Center.
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Publications
Alfaro, MP, Deskins, DL, Wallus, M, DasGupta, J, Davidson, JM, Nanney, LB, A Guney, M, Gannon, M, Young, PP. A physiological role for connective tissue growth factor in early wound healing. Lab Invest, 93(1), 81-95, 2013.

Rodriguez-Feo, CL, Sexton, KW, Boyer, RB, Pollins, AC, Cardwell, NL, Nanney, LB, Shack, RB, Mikesh, MA, McGill, CH, Driscoll, CW, Bittner, GD, Thayer, WP. Blocking the P2X7 receptor improves outcomes after axonal fusion. J Surg Res, , , 2013.

Sexton, KW, Pollins, AC, Cardwell, NL, Del Corral, GA, Bittner, GD, Shack, RB, Nanney, LB, Thayer, WP. Hydrophilic polymers enhance early functional outcomes after nerve autografting. J Surg Res, 177(2), 392-400, 2012.

Spear, ME, Nanney, LB, Phillips, S, Donahue, R, Rogers, KM, Wendel, JJ, Summit, B, Kelly, K, Shack, RB, Hagan, KF. The impact of reduction mammaplasty on breast sensation: an analysis of multiple surgical techniques. Ann Plast Surg, 68(2), 142-9, 2012.

Adolph, EJ, Hafeman, AE, Davidson, JM, Nanney, LB, Guelcher, SA. Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds. J Biomed Mater Res A, , , 2011.

Hafeman, AE, Zienkiewicz, KJ, Zachman, AL, Sung, HJ, Nanney, LB, Davidson, JM, Guelcher, SA. Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds. Biomaterials, 32(2), 419-29, 2011.

Greco, JA, Pollins, AC, Boone, BE, Levy, SE, Nanney, LB. A microarray analysis of temporal gene expression profiles in thermally injured human skin. Burns, 36(2), 192-204, 2010.

Russell, SB, Russell, JD, Trupin, KM, Gayden, AE, Opalenik, SR, Nanney, LB, Broquist, AH, Raju, L, Williams, SM. Epigenetically Altered Wound Healing in Keloid Fibroblasts. J Invest Dermatol, , , 2010.

Fogerty, M, Guy, J, Barbul, A, Nanney, LB, Abumrad, NN. African Americans show increased risk for pressure ulcers: A retrospective analysis of acute care hospitals in America. Wound Repair Regen, 17(5), 678-84, 2009.

Nading, MA, Nanney, LB, Ellis, DL. Pregnancy and estrogen receptor beta expression in a large congenital nevus. Arch Dermatol, 145(6), 691-4, 2009.

Caldwell, RL, Opalenik, SR, Davidson, JM, Caprioli, RM, Nanney, LB. Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds. Wound Repair Regen, 16(3), 442-9, 2008.

Chaurand, P, Latham, JC, Lane, KB, Mobley, JA, Polosukhin, VV, Wirth, PS, Nanney, LB, Caprioli, RM. Imaging Mass Spectrometry of Intact Proteins from Alcohol-Preserved Tissue Specimens: Bypassing Formalin Fixation. J Proteome Res, , , 2008.

Fogerty, MD, Abumrad, NN, Nanney, L, Arbogast, PG, Poulose, B, Barbul, A. Risk factors for pressure ulcers in acute care hospitals. Wound Repair Regen, 16(1), 11-8, 2008.

Greco, JA, Castaldo, ET, Nanney, LB, Wendel, JJ, Summitt, JB, Kelly, KJ, Braun, SA, Hagan, KF, Shack, RB. The effect of weight loss surgery and body mass index on wound complications after abdominal contouring operations. Ann Plast Surg, 61(3), 235-42, 2008.

Greco, JA, Castaldo, ET, Nanney, LB, Wu, YC, Donahue, R, Wendel, JJ, Hagan, KF, Shack, RB. Autologous breast reconstruction: the Vanderbilt experience (1998 to 2005) of independent predictors of displeasing outcomes. J Am Coll Surg, 207(1), 49-56, 2008.

Nading, MA, Nanney, LB, Boyd, AS, Ellis, DL. Estrogen receptor beta expression in nevi during pregnancy. Exp Dermatol, 17(6), 489-97, 2008.

Nanney, LB, Woodrell, CD, Greives, MR, Cardwell, NL, Pollins, AC, Bancroft, TA, Chesser, A, Michalak, M, Rahman, M, Siebert, JW, Gold, LI. Calreticulin enhances porcine wound repair by diverse biological effects. Am J Pathol, 173(3), 610-30, 2008. PMCID:2527067

Wilmink, GJ, Opalenik, SR, Beckham, JT, Abraham, AA, Nanney, LB, Mahadevan-Jansen, A, Davidson, JM, Jansen, ED. Molecular Imaging-Assisted Optimization of Hsp70 Expression during Laser-Induced Thermal Preconditioning for Wound Repair Enhancement. J Invest Dermatol, , , 2008.

Wilmink, GJ, Opalenik, SR, Beckham, JT, Mackanos, MA, Nanney, LB, Contag, CH, Davidson, JM, Jansen, ED. In-vivo optical imaging of hsp70 expression to assess collateral tissue damage associated with infrared laser ablation of skin. J Biomed Opt, 13(5), 054066, 2008.

Caldwell, RL, Opalenik, SR, Davidson, JM, Caprioli, RM, Nanney, LB. Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds. Wound Repair Regen, , , 2007.

Kantrow, SM, Boyd, AS, Ellis, DL, Nanney, LB, Richmond, A, Shyr, Y, Robbins, JB. Expression of activated Akt in benign nevi, Spitz nevi and melanomas. J Cutan Pathol, 34(8), 593-6, 2007. PMCID:2665272

Okwueze, MI, Cardwell, NL, Pollins, AC, Nanney, LB. Modulation of porcine wound repair with a transfected ErbB3 gene and relevant EGF-like ligands. J Invest Dermatol, 127(5), 1030-41, 2007.

Okwueze, MI, Cardwell, NL, Wolfort, SL, Nanney, LB. Unexpected motor axons in the distal superficial radial and posterior interosseous nerves: a cadaver study. Clin Anat, 20(7), 790-4, 2007.

Pollins, AC, Friedman, DB, Nanney, LB. Proteomic investigation of human burn wounds by 2D-difference gel electrophoresis and mass spectrometry. J Surg Res, 142(1), 143-52, 2007. PMCID:2696121

Rauth, TP, Poulose, BK, Davidson, JM, Nanney, LB, Holzman, MD. Mechanical abrasion improves early incorporation of small intestinal submucosa. Am Surg, 73(7), 647-51; discussion 651, 2007.

Rauth, TP, Poulose, BK, Nanney, LB, Holzman, MD. A comparative analysis of expanded polytetrafluoroethylene and small intestinal submucosa--implications for patch repair in ventral herniorrhaphy. J Surg Res, 143(1), 43-9, 2007.

Meier, K, Nanney, LB. Emerging new drugs for scar reduction. Expert Opin Emerg Drugs, 11(1), 39-47, 2006.

Meier, K, Nanney, LB. Emerging new drugs for wound repair. Expert Opin Emerg Drugs, 11(1), 23-37, 2006.

Nanney, LB, Caldwell, RL, Pollins, AC, Cardwell, NL, Opalenik, SR, Davidson, JM. Novel approaches for understanding the mechanisms of wound repair. J Invest Dermatol, 126 Suppl, 132-9, 2006.

Nanney, LB, Caldwell, RL, Pollins, AC, Cardwell, NL, Opalenik, SR, Davidson, JM. Novel approaches for understanding the mechanisms of wound repair. J Investig Dermatol Symp Proc, 11(1), 132-9, 2006.

Okwueze, MI, Spear, ME, Zwyghuizen, AM, Bra??n, SA, Ajmal, N, Nanney, LB, Hagan, KF, Wolfort, SF, Shack, RB. Effect of augmentation mammaplasty on breast sensation. Plast Reconstr Surg, 117(1), 73-83; discussion 84-5, 2006.

Schmidt, AN, Nanney, LB, Boyd, AS, King, LE, Ellis, DL. Oestrogen receptor-beta expression in melanocytic lesions. Exp Dermatol, 15(12), 971-80, 2006.

Spindler, KP, Murray, MM, Devin, C, Nanney, LB, Davidson, JM. The central ACL defect as a model for failure of intra-articular healing. J Orthop Res, 24(3), 401-406, 2006.

Nanney, L. Looking beneath the surface--setting the stage for skin ulceration. J Invest Dermatol, 125(2), vii-viii, 2005.

Poulose BK, Scholz S, Moore DE, Schmidt CR, Grogan EL, Lao OB, Nanney L, Davidson J, Holzman MD . Physiologic properties of porcine small intestine submucosa used as a bioprosthesis. J Surg, 123, 262-267, 2005.

Poulose, BK, Scholz, S, Moore, DE, Schmidt, CR, Grogan, EL, Lao, OB, Nanney, L, Davidson, J, Holzman, MD. Physiologic properties of small intestine submucosa. J Surg Res, 123(2), 262-7, 2005.

Su, Y, Raghuwanshi, SK, Yu, Y, Nanney, LB, Richardson, RM, Richmond, A. Altered CXCR2 signaling in beta-arrestin-2-deficient mouse models. J Immunol, 175(8), 5396-402, 2005. PMCID:2668249

Mikaelian, I, Nanney, LB, Parman, KS, Kusewitt, DF, Ward, JM, N??f, D, Krupke, DM, Eppig, JT, Bult, CJ, Seymour, R, Ichiki, T, Sundberg, JP. Antibodies that label paraffin-embedded mouse tissues: a collaborative endeavor. Toxicol Pathol, 32(2), 181-91, 2004.

Organ, EL, Nalbantyan, CD, Nanney, LB, Woodward, SC, Sheng, J, Dubois, RN, Price, J, Sutcliffe, M, Coffey, RJ, Rubin, DH. Effects of transforming growth factor-alpha (TGF-alpha) in vitro and in vivo on reovirus replication. DNA Cell Biol, 23(7), 430-41, 2004.

Schneider, C, Strayhorn, WD, Brantley, DM, Nanney, LB, Yull, FE, Brash, AR. Upregulation of 8-lipoxygenase in the dermatitis of IkappaB-alpha-deficient mice. J Invest Dermatol, 122(3), 691-8, 2004.

Ajmal, Nadeem, Nanney, Lillian B, Wolfort, Sean F, . Catfish spine envenomation: a case of delayed presentation.. Wilderness Environ Med, 14, 101-5, 2003.

Ajmal, Nadeem, Riordan, Colin L, Cardwell, Nancy, Nanney, Lillian B, Shack, R Bruce. The effectiveness of sodium 2-mercaptoethane sulfonate (mesna) in reducing capsular formation around implants in a rabbit model. Plast Reconstr Surg, 112(5), 1455-61; discussion 1462-3, 2003.

Ajmal, Nadeem, Riordan, Colin L, Cardwell, Nancy, Nanney, Lillian B, Shack, R Bruce. Chemically assisted capsulectomy in the rabbit model: a new approach. Plast Reconstr Surg, 112(5), 1449-54; discussion 1462-3, 2003.

Draper, Bradley K, Komurasaki, Toshi, Davidson, Mari K, Nanney, Lillian B, . Epiregulin is more potent than EGF or TGFalpha in promoting in vitro wound closure due to enhanced ERK/MAPK activation.. J Cell Biochem, 89, 1126-37, 2003.

Draper, Bradley K, Komurasaki, Toshi, Davidson, Mari K, Nanney, Lillian B, . Topical epiregulin enhances repair of murine excisional wounds.. Wound Repair Regen, 11, 188-97, 2003.

Milatovic, Snjezana, Nanney, Lillian B, Yu, Yingchun, White, John R, Richmond, Ann, . Impaired healing of nitrogen mustard wounds in CXCR2 null mice.. Wound Repair Regen, 11, 213-9, 2003. PMCID:2667443

Riordan, Colin L, McDonough, Mark, Davidson, Jeffrey M, Corley, Randall, Perlov, Cathy, Barton, Ronald, Guy, Jeffrey, Nanney, Lillian B. Noncontact laser Doppler imaging in burn depth analysis of the extremities. J Burn Care Rehabil, 24(4), 177-86, 2003.

Spindler, Kurt P, Murray, Martha M, Detwiler, Kenneth B, Tarter, Jeremy T, Dawson, John M, Nanney, Lillian B, Davidson, Jeffrey M, . The biomechanical response to doses of TGF-beta 2 in the healing rabbit medial collateral ligament.. J Orthop Res, 21, 245-9, 2003.

Draper, Bradley K, Davidson, Mari K, Nanney, Lillian B, . MMPs and TIMP-1 are differentially expressed between acute murine excisional and laser wounds.. Lasers Surg Med, 30, 106-16, 2002.

Du, Jianguo, Luan, Jing, Liu, Hua, Daniel, Thomas O, Peiper, Stephen, Chen, Theresa S, Yu, Yingchun, Horton, Linda W, Nanney, Lillian B, Strieter, Robert M, Richmond, Ann, . Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress.. J Leukoc Biol, 71, 141-53, 2002. PMCID:2665273

Nanney, Lillian B, Bennett, Laura L, . Comparative evaluation of topical antiseptic/antimicrobial treatment on aspects of wound repair in the porcine model.. Ostomy Wound Manage, Suppl, 14-9, 2002.

Riordan, Colin L, Nanney, Lillian B, Upton, Joseph, Wolfort, Sean F, . Vascularized medial sural cutaneous nerve based on the superficial sural artery: a reliable nerve graft.. J Reconstr Microsurg, 18, 147-52; discussion 153-4, 2002.

Roman, CD, Choy, H, Nanney, L, Riordan, C, Parman, K, Johnson, D, Beauchamp, RD. Vascular endothelial growth factor-mediated angiogenesis inhibition and postoperative wound healing in rats. J Surg Res, 105(1), 43-7, 2002.

Spindler, K P, Dawson, J M, Stahlman, G C, Davidson, J M, Nanney, L B, . Collagen expression and biomechanical response to human recombinant transforming growth factor beta (rhTGF-beta2) in the healing rabbit MCL.. J Orthop Res, 20, 318-24, 2002.

Weinstein, David D, Spector, Sydney, Nanney, Lillian B, King, Lloyd E, . Endogenous opiate alkaloids and human skin.. J Invest Dermatol, 119, 709-10, 2002.

Adcock, D, Paulsen, S, Jabour, K, Davis, S, Nanney, L B, Shack, R B, . Analysis of the effects of deep mechanical massage in the porcine model.. Plast Reconstr Surg, 108, 233-40, 2001.

Bennett, L L, Rosenblum, R S, Perlov, C, Davidson, J M, Barton, R M, Nanney, L B, . An in vivo comparison of topical agents on wound repair.. Plast Reconstr Surg, 108, 675-87, 2001.

Deane, N G, Parker, M A, Aramandla, R, Diehl, L, Lee, W J, Washington, M K, Nanney, L B, Shyr, Y, Beauchamp, R D, . Hepatocellular carcinoma results from chronic cyclin D1 overexpression in transgenic mice.. Cancer Res, 61, 5389-95, 2001.

Nanney, L B, Wamil, B D, Whitsitt, J, Cardwell, N L, Davidson, J M, Yan, H P, Hellerqvist, C G, . CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism.. Angiogenesis, 4, 61-70, 2001.

Chen, C L, Yull, F E, Cardwell, N, Singh, N, Strayhorn, W D, Nanney, L B, Kerr, L D, . RAG2-/-, I kappa B-alpha-/- chimeras display a psoriasiform skin disease.. J Invest Dermatol, 115, 1124-33, 2000.

Devalaraja, R M, Nanney, L B, Du, J, Qian, Q, Yu, Y, Devalaraja, M N, Richmond, A, . Delayed wound healing in CXCR2 knockout mice.. J Invest Dermatol, 115, 234-44, 2000. PMCID:2664868

Haghnegahdar, H, Du, J, Wang, D, Strieter, R M, Burdick, M D, Nanney, L B, Cardwell, N, Luan, J, Shattuck-Brandt, R, Richmond, A. The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. J Leukoc Biol, 67(1), 53-62, 2000. PMCID:2669312

Nanney, L B, Paulsen, S, Davidson, M K, Cardwell, N L, Whitsitt, J S, Davidson, J M, . Boosting epidermal growth factor receptor expression by gene gun transfection stimulates epidermal growth in vivo.. Wound Repair Regen, 8, 117-27, 2000.

Nirodi, C S, Devalaraja, R, Nanney, L B, Arrindell, S, Russell, S, Trupin, J, Richmond, A, . Chemokine and chemokine receptor expression in keloid and normal fibroblasts.. Wound Repair Regen, 8, 371-82, 2000.

Brash, A R, Jisaka, M, Boeglin, W E, Chang, M S, Keeney, D S, Nanney, L B, Kasper, S, Matusik, R J, Olson, S J, Shappell, S B, . Investigation of a second 15S-lipoxygenase in humans and its expression in epithelial tissues.. Adv Exp Med Biol, 469, 83-9, 1999.

Garrard, CL, Clements, RH, Nanney, L, Davidson, JM, Richards, WO. Adhesion formation is reduced after laparoscopic surgery. Surg Endosc, 13(1), 10-3, 1999.

Johnson, E N, Nanney, L B, Virmani, J, Lawson, J A, Funk, C D. Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice. J Invest Dermatol, 112(6), 861-5, 1999.

Adcock, D, Paulsen, S, Davis, S, Nanney, L, Shack, RB. Analysis of the cutaneous and systemic effects of Endermologie in the porcine model. Aesthet Surg J, 18(6), 414-20, 1998.

Boyd, A S, Nanney, L B, King, L E. Immunoperoxidase evaluation of lichen planus biopsies for hepatitis C virus. Int J Dermatol, 37(4), 260-2, 1998.

Keeney, D S, Skinner, C, Travers, J B, Capdevila, J H, Nanney, L B, King, L E, Waterman, M R. Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J Biol Chem, 273(48), 32071-9, 1998.

Nanney, L B, Skeel, A, Luan, J, Polis, S, Richmond, A, Wang, M H, Leonard, E J. Proteolytic cleavage and activation of pro-macrophage-stimulating protein and upregulation of its receptor in tissue injury. J Invest Dermatol, 111(4), 573-81, 1998.

Paulsen, S M, Nanney, L B, Lynch, J B. Titanium tetrachloride: an unusual agent with the potential to create severe burns. J Burn Care Rehabil, 19(5), 377-81, 1998.

Paulsen, S M, Wurster, S H, Nanney, L B. Expression of inducible nitric oxide synthase in human burn wounds. Wound Repair Regen, 6(2), 142-8, 1998.

Boyd, A, Nanney, L, Cameron, G, King, L. Expression of bcl-2 in lichen planus, acute graft-versus-host disease, and erythema multiforme. Am J Dermatopathol, 19(1), 46-51, 1997.

Charous, S J, Stricklin, G P, Nanney, L B, Netterville, J L, Burkey, B B. Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases in head and neck squamous cell carcinoma. Ann Otol Rhinol Laryngol, 106(4), 271-8, 1997.

Jisaka, M, Kim, R B, Boeglin, W E, Nanney, L B, Brash, A R. Molecular cloning and functional expression of a phorbol ester-inducible 8S-lipoxygenase from mouse skin. J Biol Chem, 272(39), 24410-6, 1997.

Nanney, L B, Davidson, M K, Gates, R E, Kano, M, King, L E. Altered distribution and expression of protein tyrosine phosphatases in normal human skin as compared to squamous cell carcinomas. J Cutan Pathol, 24(9), 521-32, 1997.

Zhang, T, Nanney, L B, Luongo, C, Lamps, L, Heppner, K J, DuBois, R N, Beauchamp, R D. Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients. Cancer Res, 57(1), 169-75, 1997.

Zhang, T, Nanney, L B, Peeler, M O, Williams, C S, Lamps, L, Heppner, K J, DuBois, R N, Beauchamp, R D. Decreased transforming growth factor beta type II receptor expression in intestinal adenomas from Min/+ mice is associated with increased cyclin D1 and cyclin-dependent kinase 4 expression. Cancer Res, 57(9), 1638-43, 1997.

Benn, S I, Whitsitt, J S, Broadley, K N, Nanney, L B, Perkins, D, He, L, Patel, M, Morgan, J R, Swain, W F, Davidson, J M. Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin. J Clin Invest, 98(12), 2894-902, 1996. PMCID:507757

Nanney, L B, Sundberg, J P, King, L E. Increased epidermal growth factor receptor in fsn/fsn mice. J Invest Dermatol, 106(6), 1169-74, 1996.

Nanney, L B, Wenczak, B A, Lynch, J B. Progressive burn injury documented with vimentin immunostaining. J Burn Care Rehabil, 17(3), 191-8, 1996.

Schaffer, C J, Nanney, L B. Cell biology of wound healing. Int Rev Cytol, 169, 151-81, 1996.

Spindler, K P, Clark, S W, Nanney, L B, Davidson, J M. Expression of collagen and matrix metalloproteinases in ruptured human anterior cruciate ligament: an in situ hybridization study. J Orthop Res, 14(6), 857-61, 1996.

Williams, C S, Luongo, C, Radhika, A, Zhang, T, Lamps, L W, Nanney, L B, Beauchamp, R D, DuBois, R N. Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology, 111(4), 1134-40, 1996.

Blessing, M, Nanney, L B, King, L E, Hogan, B L. Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene. Teratog Carcinog Mutagen, 15(1), 11-21, 1995.

Morita, K, Hogan, M E, Nanney, L B, King, L E, Manabe, M, Sun, T T, Sundberg, J P. Cutaneous ultrastructural features of the flaky skin (fsn) mouse mutation. J Dermatol, 22(6), 385-95, 1995.

Nanney, L B, Mueller, S G, Bueno, R, Peiper, S C, Richmond, A. Distributions of melanoma growth stimulatory activity of growth-regulated gene and the interleukin-8 receptor B in human wound repair. Am J Pathol, 147(5), 1248-60, 1995. PMCID:1869526

Nanney, LB, Fortney, DZ, Durham, DR. Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness burn wounds. Wound Repair Regen, 3(4), 442-8, 1995.

Roesel, J F, Nanney, L B. Assessment of differential cytokine effects on angiogenesis using an in vivo model of cutaneous wound repair. J Surg Res, 58(5), 449-59, 1995.

Spindler, KP, Nanney, LB, Davidson, JM. Proliferative responses to platelet-derived growth factor in young and old rat patellar tendon. Connect Tissue Res, 31(2), 171-7, 1995.

Gates, R E, King, L E, Hanks, S K, Nanney, L B. Potential role for focal adhesion kinase in migrating and proliferating keratinocytes near epidermal wounds and in culture. Cell Growth Differ, 5(8), 891-9, 1994.

Gunaratne, P, Stoscheck, C, Gates, R E, Li, L, Nanney, L B, King, L E. Protein tyrosyl phosphatase-1B is expressed by normal human epidermis, keratinocytes, and A-431 cells and dephosphorylates substrates of the epidermal growth factor receptor. J Invest Dermatol, 103(5), 701-6, 1994.

Nanney, L B, Coffey, R J, Ellis, D L. Expression and distribution of transforming growth factor-alpha within melanocytic lesions. J Invest Dermatol, 103(5), 707-14, 1994.

Stricklin, G P, Li, L, Nanney, L B. Localization of mRNAs representing interstitial collagenase, 72-kda gelatinase, and TIMP in healing porcine burn wounds. J Invest Dermatol, 103(3), 352-8, 1994.

Stricklin, G P, Nanney, L B. Immunolocalization of collagenase and TIMP in healing human burn wounds. J Invest Dermatol, 103(4), 488-92, 1994.

Blessing, M, Nanney, L B, King, L E, Jones, C M, Hogan, B L. Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. Genes Dev, 7(2), 204-15, 1993.

Dominey, A M, Wang, X J, King, L E, Nanney, L B, Gagne, T A, Sellheyer, K, Bundman, D S, Longley, M A, Rothnagel, J A, Greenhalgh, D A. Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ, 4(12), 1071-82, 1993.

Durham, D R, Fortney, D Z, Nanney, L B. Preliminary evaluation of vibriolysin, a novel proteolytic enzyme composition suitable for the debridement of burn wound eschar. J Burn Care Rehabil, 14(5), 544-51, 1993.

Fava, R A, Nanney, L B, Wilson, D, King, L E. Annexin-1 localization in human skin: possible association with cytoskeletal elements in keratinocytes of the stratum spinosum. J Invest Dermatol, 101(5), 732-7, 1993.

Levine, J H, Moses, H L, Gold, L I, Nanney, L B. Spatial and temporal patterns of immunoreactive transforming growth factor beta 1, beta 2, and beta 3 during excisional wound repair. Am J Pathol, 143(2), 368-80, 1993. PMCID:1887040

Molina, P E, Eltayeb, K, Hourani, H, Okamura, K, Nanney, L B, Williams, P, Abumrad, N N. Hormonal and metabolic effects of neuroglucopenia. Brain Res, 614(1-2), 99-108, 1993.

Quaglino, D, Fornieri, C, Nanney, L B, Davidson, J M. Extracellular matrix modifications in rat tissues of different ages. Correlations between elastin and collagen type I mRNA expression and lysyl-oxidase activity. Matrix, 13(6), 481-90, 1993.

Stricklin, G P, Li, L, Jancic, V, Wenczak, B A, Nanney, L B. Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds. Am J Pathol, 143(6), 1657-66, 1993. PMCID:1887264

Tettelbach, W, Nanney, L, Ellis, D, King, L, Richmond, A. Localization of MGSA/GRO protein in cutaneous lesions. J Cutan Pathol, 20(3), 259-66, 1993.

Wenczak, B, Nanney, LB. Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds. Wound Repair Regen, 1(4), 219-30, 1993.

Ellis, D L, King, L E, Nanney, L B. Increased epidermal growth factor receptors in melanocytic lesions. J Am Acad Dermatol, 27(4), 539-46, 1992.

Nanney, L B, Ellis, D L, Levine, J, King, L E. Epidermal growth factor receptors in idiopathic and virally induced skin diseases. Am J Pathol, 140(4), 915-25, 1992. PMCID:1886376

Nanney, L B, Gates, R E, Todderud, G, King, L E, Carpenter, G. Altered distribution of phospholipase C-gamma 1 in benign hyperproliferative epidermal diseases. Cell Growth Differ, 3(4), 233-9, 1992.

Nanney, L B, Yates, R A, King, L E. Modulation of epidermal growth factor receptors in psoriatic lesions during treatment with topical EGF. J Invest Dermatol, 98(3), 296-301, 1992.

Romano, M, Polk, W H, Awad, J A, Arteaga, C L, Nanney, L B, Wargovich, M J, Kraus, E R, Boland, C R, Coffey, R J. Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo. J Clin Invest, 90(6), 2409-21, 1992. PMCID:443397

Stoscheck, C M, Nanney, L B, King, L E. Quantitative determination of EGF-R during epidermal wound healing. J Invest Dermatol, 99(5), 645-9, 1992.

Wenczak, B A, Lynch, J B, Nanney, L B. Epidermal growth factor receptor distribution in burn wounds. Implications for growth factor-mediated repair. J Clin Invest, 90(6), 2392-401, 1992. PMCID:443395

Birecree, E, King, L E, Nanney, L B. Epidermal growth factor and its receptor in the developing human nervous system. Brain Res Dev Brain Res, 60(2), 145-54, 1991.

Davidson, J M, Nanney, L B, Broadley, K N, Whitsett, J S, Aquino, A M, Beccaro, M, Rastrelli, A. Hyaluronate derivatives and their application to wound healing: preliminary observations. Clin Mater, 8(1-2), 171-7, 1991.

Fava, R A, Olsen, N J, Postlethwaite, A E, Broadley, K N, Davidson, J M, Nanney, L B, Lucas, C, Townes, A S. Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med, 173(5), 1121-32, 1991. PMCID:2118851

King, L E, Holbrook, K A, Stoscheck, C, Underwood, R A, Nanney, L B. Growth factor receptors and hair loss. J Invest Dermatol, 96(5), 79S, 1991.

Quaglino, D, Nanney, L B, Ditesheim, J A, Davidson, J M. Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model. J Invest Dermatol, 97(1), 34-42, 1991.

Reilly, M K, Perry, M O, Nanney, L B. True ablation of atheromatous plaques with laser energy. A phase I safety study. Ann Surg, 213(5), 440-4; discussion 444-5, 1991. PMCID:1358469

Yates, R A, Nanney, L B, Gates, R E, King, L E. Epidermal growth factor and related growth factors. Int J Dermatol, 30(10), 687-94, 1991.

Ellis, D L, Nanney, L B, King, L E. Increased epidermal growth factor receptors in seborrheic keratoses and acrochordons of patients with the dysplastic nevus syndrome. J Am Acad Dermatol, 23(6 Pt 1), 1070-7, 1990.

Fava, R A, Casey, T T, Wilcox, J, Pelton, R W, Moses, H L, Nanney, L B. Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules. Blood, 76(10), 1946-55, 1990.

King, L E, Gates, R E, Stoscheck, C M, Nanney, L B. The EGF/TGF alpha receptor in skin. J Invest Dermatol, 94(6 Suppl), 164S-170S, 1990.

King, L E, Gates, R E, Stoscheck, C M, Nanney, L B. Epidermal growth factor/transforming growth factor alpha receptors and psoriasis. J Invest Dermatol, 95(5), 10S-12S, 1990.

King, LE, Gates, RE, Stoscheck, CM, Nanney, LB. Epidermal growth factor/transforming growth factor alpha receptors and psoriasis. J Invest Dermatol, 95(5 Suppl), 10S-2S, 1990.

Nanney, L B. Epidermal and dermal effects of epidermal growth factor during wound repair. J Invest Dermatol, 94(5), 624-9, 1990.

Nanney, L B, King, L E, Dale, B A. Epidermal growth factor receptors in genetically induced hyperproliferative skin disorders. Pediatr Dermatol, 7(4), 256-65, 1990.

Nanney, L B, Stoscheck, C M, King, L E, Underwood, R A, Holbrook, K A. Immunolocalization of epidermal growth factor receptors in normal developing human skin. J Invest Dermatol, 94(6), 742-8, 1990.

Nanney, L. B., Stoscheck, C. M., King, L. E., Underwood, R. A., and Holbrook, C. A. Immuno localization of epidermal growth factor receptors in normal developing human skin. J. Invest. Dermat., 94, 742-848, 1990.

Quaglino, D, Nanney, L B, Kennedy, R, Davidson, J M. Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin. I. Excisional wound model. Lab Invest, 63(3), 307-19, 1990.

Quaglino, D., Nanney, L. B., Kennedy, R., and Davidson, J. M. Transforming growth factor b stimulates wound healing and modulates extracellular matrix gene expression in pig skin. Lab. Invest., 63, 307-319 , 1990.

Brown, G L, Nanney, L B, Griffen, J, Cramer, A B, Yancey, J M, Curtsinger, L J, Holtzin, L, Schultz, G S, Jurkiewicz, M J, Lynch, J B. Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med, 321(2), 76-9, 1989.

Birecree, E, Whetsell, W O, Stoscheck, C, King, L E, Nanney, L B. Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease. J Neuropathol Exp Neurol, 47(5), 549-60, 1988.

King, L E, Ellis, D L, Gates, R E, Inman, W H, Stoscheck, C M, Fava, R A, Nanney, L B. The role of epidermal growth factor in skin diseases. Am J Med Sci, 296(3), 154-8, 1988.

Nanney, L B, Stoscheck, C M, King, L E. Characterization of binding and receptors for epidermal growth factor in smooth muscle. Cell Tissue Res, 254(1), 125-32, 1988.

Werner, M H, Nanney, L B, Stoscheck, C M, King, L E. Localization of immunoreactive epidermal growth factor receptors in human nervous system. J Histochem Cytochem, 36(1), 81-6, 1988.

Ellis, D L, Kafka, S P, Chow, J C, Nanney, L B, Inman, W H, McCadden, M E, King, L E. Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Tr??lat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes. N Engl J Med, 317(25), 1582-7, 1987.

Healy, D A, Merrill, W H, Nanney, L B, Smith, B M. The influence of preservation techniques on prostacyclin biosynthesis in venous autografts. Curr Surg, 43(2), 103-5, 1986.

Nanney, L B, Stoscheck, C M, Magid, M, King, L E. Altered [125I]epidermal growth factor binding and receptor distribution in psoriasis. J Invest Dermatol, 86(3), 260-5, 1986.

Nanney, L. B., Stoscheck, C. M., and King, L. E. Altered 1251-epidermal growth factor binding and receptor distribution in psoriasis. J. Invest. Dermat., 86, 260-265, 1986.

Rees, R S, Nanney, L B, Fleming, P, Cary, A. Tissue expansion: its role in traumatic below-knee amputations. Plast Reconstr Surg, 77(1), 133-7, 1986.

Magid, M, Nanney, L B, Stoscheck, C M, King, L E. Epidermal growth factor binding and receptor distribution in term human placenta. Placenta, 6(6), 519-26, 1985.

Rees, R S, Reilley, A F, Nanney, L B, Lynch, J B. Sacral pressure sores: treatment with island gluteus maximus musculocutaneous flaps. South Med J, 78(10), 1147-51, 1985.

Nanney, L B, Magid, M, Stoscheck, C M, King, L E. Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol, 83(5), 385-93, 1984.

Nanney, L B, McKanna, J A, Stoscheck, C M, Carpenter, G, King, L E. Visualization of epidermal growth factor receptors in human epidermis. J Invest Dermatol, 82(2), 165-9, 1984.

Nanney, L. B., Magid, M., Stoscheck, C. M., and King, L. E. Epidermal growth factor binding and receptor distribution in normal human skin and appendages. J. Invest. Dermat., , 385-393, 1984.

Rees, R S, Nanney, L B, Yates, R A, King, L E. Interaction of brown recluse spider venom on cell membranes: the inciting mechanism. J Invest Dermatol, 83(4), 270-5, 1984.

Nanney, L B, Newton, E D, Franklin, J D, Rees, R S, Lynch, J B. Venous endothelial changes after experimental cooling of free flaps. J Surg Res, 34(3), 271-8, 1983.

Nanney, L B. Changes in the microvasculature of skin subjected to thermal injury. Burns Incl Therm Inj, 8(5), 321-7, 1982.

Nanney, L B. Histochemical alterations in severely burned guinea pig skin. Plast Reconstr Surg, 68(5), 753-9, 1981.

Nanney, L B. The effects of severe thermal injury on the glycosaminoglycans of guinea pig skin. J Invest Dermatol, 76(4), 227-30, 1981.


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Postdoctoral Position Details
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Updated Date
07/26/2013



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