Vanderbilt University School of Medicine

Roberts, L. Jackson , M.D.
Professor of Pharmacology
William Stokes Chair in Experimental Therapeutics
Professor of Medicine

Lab Url: N/A

Phone Number: 615-322-3203

Email Address:jack.roberts@vanderbilt.edu

Roberts, L.'s picture

Office Address   Mailing Address

522-A Robinson Research Building

522-A RRB 37232-6602


Research Keywords
Oxidative stress, Isoprostanes, Antioxidants, Biochemistry, Mass spectroscopy,

Research Specialty
Role of Free Radicals and Oxidative Injury in Human Disease

Research Description
Free radicals primarily derived from oxygen have been implicated in a wide variety of diseases ranging from atherosclerosis, cancer, neurodegenerative diseases, and even the normal aging process. Free radicals readily attack lipids, proteins, and DNA resulting in mutations and deleterious effects on membrane and protein structure and function.

We discovered a series of novel products of free radical attack on lipids termed isoprostanes. Measurement of isoprostanes has emerged as the most reliable approach to assess free radical reactions in vivo. They also exert potent biological activities, which are currently being characterized. We have also discovered a series of similar compounds (neuroprostanes) formed by free radical attack on a unique lipid in the brain. Their role in neurodegenerative diseases is currently under investigation. Recently, we discovered novel highly reactive molecules that are produced by these pathways. These molecules rapidly adduct to proteins and we are currently exploring the pathobiological consequences of their formation in neurodegenerative and other diseases. More recently, we discovered new products of lipid peroxidation called isofurans whose formation is uniquely regulated by oxygen tension. Measurement of isofurans provides a unique tool to assess the role of oxidative injury in the setting of hyperoxia and in disorders of mitochondrial dysfunction. This provides ample opportunities for scientific investigation in a multidisciplinary area of research that is highly relevant to human disease. .

Publications
Salahudeen AK, Oliver B, Bower J, and Roberts LJ, II. Increase in plasma esterified F2-isoprostanes following intravenous iron infusion in patients on hemodialysis. Kidney Int. 60:1525-1531, 2001

Przybysz, AJ, Choe, KP, Roberts, LJ, Strange, K. Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone. Mech Ageing Dev, 130(6), 357-69, 2009. PMCID:2680786

Roberts, LJ, Milne, GL. Isoprostanes. J Lipid Res, 50 Suppl, S219-23, 2009. PMCID:2674741

Guo Z, Ran Q, Roberts LJ 2nd, Zhou L, Richardson A, Sharan C, Wu D, Yang H. Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice. Free Radic Biol Med, 44(3), 343-52, 2008.

Han ES, Muller FL, Perez V, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. The in vivo gene expression signature of oxidative stress. Physiol Genomics, 34(1), 112-26, 2008.

Hartert, TV, Deng, X, Hartman, TJ, Wen, W, Yang, G, Gao, YT, Jin, M, Bai, C, Gross, M, Roberts, LJ, Sheller, JR, Christman, J, Dupont, W, Griffin, M, Shu, XO. The Shanghai Women''s Asthma and Allergy Study: objectives, design, and recruitment results. Am J Epidemiol, 167(11), 1387-96, 2008. PMCID:2430736

Patel M, Liang LP, Hou H, Williams BB, Kmiec M, Swartz HM, Fessel JP, Roberts LJ 2nd.. Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension. J Neurochem, 104(1), 264-70, 2008.

Powers JS, Roberts LJ 2nd, Tarvin E, Hongu N, Choi L, Buchowski M. Oxidative stress and multi-organ failure in hospitalized elderly people. J Am Geriatr Soc, 56(6), 1150-2, 2008.

Roberts, LJ. Inhibition of heme protein redox cycling: reduction of ferryl heme by iron chelators and the role of a novel through-protein electron transfer pathway. Free Radic Biol Med, 44(3), 257-60, 2008.

Roberts, LJ, II. In Memoriam: Jason D. Morrow, MD (1957-2008). Free Rad Biol Med, 45, 1203-1205, 2008.

Arneson, KO, Roberts, LJ. Measurement of products of docosahexaenoic acid peroxidation, neuroprostanes, and neurofurans. Methods Enzymol, 433, 127-43, 2007.

Boyden, PA, Davies, SS, Viswanathan, PC, Amarnath, V, Balser, JR, Roberts, LJ. Potential role of isoketals formed via the isoprostane pathway of lipid peroxidation in ischemic arrhythmias. J Cardiovasc Pharmacol, 50(5), 480-6, 2007.

Davies, SS, Amarnath, V, Brame, CJ, Boutaud, O, Roberts, LJ. Measurement of chronic oxidative and inflammatory stress by quantification of isoketal/levuglandin gamma-ketoaldehyde protein adducts using liquid chromatography tandem mass spectrometry. Nat Protoc, 2(9), 2079-91, 2007.

Frisard, MI, Broussard, A, Davies, SS, Roberts, LJ, Rood, J, de Jonge, L, Fang, X, Jazwinski, SM, Deutsch, WA, Ravussin, E, , . Aging, resting metabolic rate, and oxidative damage: results from the Louisiana Healthy Aging Study. J Gerontol A Biol Sci Med Sci, 62(7), 752-9, 2007. PMCID:2692620

Ivester, P, Roberts, LJ, Young, T, Stafforini, D, Vivian, J, Lees, C, Young, J, Daunais, J, Friedman, D, Rippe, RA, Parsons, CJ, Grant, KA, Cunningham, C. Ethanol self-administration and alterations in the livers of the cynomolgus monkey, Macaca fascicularis. Alcohol Clin Exp Res, 31(1), 144-55, 2007.

Montuschi, P, Barnes, P, Roberts, LJ. Insights into oxidative stress: the isoprostanes. Curr Med Chem, 14(6), 703-17, 2007.

Roberts, LJ, Oates, JA, Linton, MF, Fazio, S, Meador, BP, Gross, MD, Shyr, Y, Morrow, JD. The relationship between dose of vitamin E and suppression of oxidative stress in humans. Free Radic Biol Med, 43(10), 1388-93, 2007. PMCID:2072864

Wu, P, Roberts, LJ, Shintani, AK, Sheller, JR, Minton, PA, Higgins, SB, Hartert, TV. Changes in urinary dinor dihydro F(2)-isoprostane metabolite concentrations, a marker of oxidative stress, during and following asthma exacerbations. Free Radic Res, 41(9), 956-62, 2007.

Cotton, RB, Hazinski, TA, Morrow, JD, Roberts, LJ, Zeldin, DC, Lindstrom, DP, Lappalainen, U, Law, AB, Steele, S. Cimetidine does not prevent lung injury in newborn premature infants. Pediatr Res, 59(6), 795-800, 2006. PMCID:2367235

Cotton, RB, Sundell, HW, Zeldin, DC, Morrow, JD, Roberts, LJ, Hazinski, TA, Law, AB, Steele, S. Inhaled nitric oxide attenuates hyperoxic lung injury in lambs. Pediatr Res, 59(1), 142-6, 2006.

Davies, SS, Brantley, EJ, Voziyan, PA, Amarnath, V, Zagol-Ikapitte, I, Boutaud, O, Hudson, BG, Oates, JA, Roberts, LJ. Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity. Biochemistry, 45(51), 15756-67, 2006. PMCID:2597444

Davies, SS, Zackert, W, Luo, Y, Cunningham, CC, Frisard, M, Roberts, LJ. Quantification of dinor,dihydro metabolites of F(2)-isoprostanes in urine by liquid chromatography/tandem mass spectrometry. Anal Biochem, 348(2), 185-91, 2006.

Dutta, UK, Lane, J, Roberts, LJ, Majid, DS. Superoxide formation and interaction with nitric oxide modulate systemic arterial pressure and renal function in salt-depleted dogs. Exp Biol Med (Maywood), 231(3), 269-76, 2006.

Gaut, JP, Belaaouaj, A, Byun, J, Roberts, LJ, Maeda, N, Frei, B, Heinecke, JW. Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. Free Radic Biol Med, 40(9), 1494-501, 2006.

Gustafson, EJ, Roberts, LJ, Leefers, LA. Linking linear programming and spatial simulation models to predict landscape effects of forest management alternatives. J Environ Manage, 81(4), 339-50, 2006.

Jakupcak, M, Roberts, LJ, Martell, C, Mulick, P, Michael, S, Reed, R, Balsam, KF, Yoshimoto, D, McFall, M. A pilot study of behavioral activation for veterans with posttraumatic stress disorder. J Trauma Stress, 19(3), 387-91, 2006.

Montgomery-Downs, HE, Krishna, J, Roberts, LJ, Gozal, D. Urinary F(2)-isoprostane metabolite levels in children with sleep-disordered breathing. Sleep Breath, 10(4), 211-5, 2006.

Muller, FL, Song, W, Liu, Y, Chaudhuri, A, Pieke-Dahl, S, Strong, R, Huang, TT, Epstein, CJ, Roberts, LJ, Csete, M, Faulkner, JA, Van Remmen, H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med, 40(11), 1993-2004, 2006.

Roberts, LJ, Cleland, LG, Thomas, R, Proudman, SM. Early combination disease modifying antirheumatic drug treatment for rheumatoid arthritis. Med J Aust, 184(3), 122-5, 2006.

Stafforini, DM, Sheller, JR, Blackwell, TS, Sapirstein, A, Yull, FE, McIntyre, TM, Bonventre, JV, Prescott, SM, Roberts, LJ. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem, 281(8), 4616-23, 2006.

Talati, M, Meyrick, B, Peebles, RS, Davies, SS, Dworski, R, Mernaugh, R, Mitchell, D, Boothby, M, Roberts, LJ, Sheller, JR. Oxidant stress modulates murine allergic airway responses. Free Radic Biol Med, 40(7), 1210-9, 2006.

Canter, JA, Eshaghian, A, Fessel, J, Summar, ML, Roberts, LJ, Morrow, JD, Sligh, JE, Haines, JL. Degree of heteroplasmy reflects oxidant damage in a large family with the mitochondrial DNA A8344G mutation. Free Radic Biol Med, 38(5), 678-83, 2005.

Fukuda, K, Davies, SS, Nakajima, T, Ong, BH, Kupershmidt, S, Fessel, J, Amarnath, V, Anderson, ME, Boyden, PA, Viswanathan, PC, Roberts, LJ, Balser, JR. Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels. Circ Res, 97(12), 1262-9, 2005.

Habbu, JH, Hayman, R, Roberts, LJ. Tuberous sclerosis in an antenatally diagnosed cardiac rhabdomyoma. J Obstet Gynaecol, 25(2), 193-4, 2005.

Idris, AH, Roberts, LJ, Caruso, L, Showstark, M, Layon, AJ, Becker, LB, Vanden Hoek, T, Gabrielli, A. Oxidant injury occurs rapidly after cardiac arrest, cardiopulmonary resuscitation, and reperfusion. Crit Care Med, 33(9), 2043-8, 2005.

Kadiiska, MB, Gladen, BC, Baird, DD, Germolec, D, Graham, LB, Parker, CE, Nyska, A, Wachsman, JT, Ames, BN, Basu, S, Brot, N, Fitzgerald, GA, Floyd, RA, George, M, Heinecke, JW, Hatch, GE, Hensley, K, Lawson, JA, Marnett, LJ, Morrow, JD, Murray, DM, Plastaras, J, Roberts, LJ, Rokach, J, Shigenaga, MK, Sohal, RS, Sun, J, Tice, RR, Van Thiel, DH, Wellner, D, Walter, PB, Tomer, KB, Mason, RP, Barrett, JC. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning. Free Radic Biol Med, 38(6), 698-710, 2005.

Kadiiska, MB, Gladen, BC, Baird, DD, Graham, LB, Parker, CE, Ames, BN, Basu, S, Fitzgerald, GA, Lawson, JA, Marnett, LJ, Morrow, JD, Murray, DM, Plastaras, J, Roberts, LJ, Rokach, J, Shigenaga, MK, Sun, J, Walter, PB, Tomer, KB, Barrett, JC, Mason, RP. Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radic Biol Med, 38(6), 711-8, 2005.

Kwan, KS, Roberts, LJ, Swalm, DM. Sexual dysfunction and chronic pain: the role of psychological variables and impact on quality of life. Eur J Pain, 9(6), 643-52, 2005.

Roberts, LJ, Fessel, JP, Davies, SS. The biochemistry of the isoprostane, neuroprostane, and isofuran Pathways of lipid peroxidation. Brain Pathol, 15(2), 143-8, 2005.

Roberts, LJ, Huffam, SE, Walton, SF, Currie, BJ. Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature. J Infect, 50(5), 375-81, 2005.

Shibao, C, Arzubiaga, C, Roberts, LJ, Raj, S, Black, B, Harris, P, Biaggioni, I. Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders. Hypertension, 45(3), 385-90, 2005.

Ward, WF, Qi, W, Van Remmen, H, Zackert, WE, Roberts, LJ, Richardson, A. Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. J Gerontol A Biol Sci Med Sci, 60(7), 847-51, 2005.

Amarnath, V, Amarnath, K, Amarnath, K, Davies, S, Roberts, LJ. Pyridoxamine: an extremely potent scavenger of 1,4-dicarbonyls. Chem Res Toxicol, 17(3), 410-5, 2004.

Bernoud-Hubac, N, Fay, LB, Armarnath, V, Guichardant, M, Bacot, S, Davies, SS, Roberts, LJ, Lagarde, M. Covalent binding of isoketals to ethanolamine phospholipids. Free Radic Biol Med, 37(10), 1604-11, 2004.

Brame, Cynthia J., Boutaud, Olivier, Davies, Sean S., Yang, Tao, Oates, John A., Roden, Dan, Roberts, L. Jackson. Modifcation of proteins by isoketal-containing oxidized phospholipids. J Biol Chem, 279, 13447-13451, 2004.

Browne, SE, Roberts, LJ, Dennery, PA, Doctrow, SR, Beal, MF, Barlow, C, Levine, RL. Treatment with a catalytic antioxidant corrects the neurobehavioral defect in ataxia-telangiectasia mice. Free Radic Biol Med, 36(7), 938-42, 2004.

Carey, KB, Roberts, LJ, Kivlahan, DR, Carey, MP, Neal, DJ. Problems assessment for substance using psychiatric patients: development and initial psychometric evaluation. Drug Alcohol Depend, 75(1), 67-77, 2004.

Davies, SS, Amarnath, V, Roberts, LJ. Isoketals: highly reactive gamma-ketoaldehydes formed from the H2-isoprostane pathway. Chem Phys Lipids, 128(1-2), 85-99, 2004.

Davies, SS, Talati, M, Wang, X, Mernaugh, RL, Amarnath, V, Fessel, J, Meyrick, BO, Sheller, J, Roberts, LJ. Localization of isoketal adducts in vivo using a single-chain antibody. Free Radic Biol Med, 36(9), 1163-74, 2004.

Elso, CM, Roberts, LJ, Smyth, GK, Thomson, RJ, Baldwin, TM, Foote, SJ, Handman, E. Leishmaniasis host response loci (lmr1-3) modify disease severity through a Th1/Th2-independent pathway. Genes Immun, 5(2), 93-100, 2004.

Friel, JK, Friesen, RW, Harding, SV, Roberts, LJ. Evidence of oxidative stress in full-term healthy infants. Pediatr Res, 56(6), 878-82, 2004.

Hou, Xin, Roberts, L Jackson, Gobeil, Fernand, Taber, DouglasF, Kanai, Kazuo, Abran, Daniel, Brault, Sonia, Checchin, Daniella, Sennlaub, Florian, Lachapelle, Pierre, Varma, DayaR, Chemtob, Sylvain. Isomer-specific contractile effects of a series of synthetic f2-isoprostanes on retinal and cerebral microvasculature. Free Radic Biol Med, 36(2), 163-72, 2004.

Ilsley, JN, Belinsky, GS, Guda, K, Zhang, Q, Huang, X, Blumberg, JB, Milbury, PE, Roberts, LJ, Stevens, RG, Rosenberg, DW. Dietary iron promotes azoxymethane-induced colon tumors in mice. Nutr Cancer, 49(2), 162-9, 2004.

Lim, E, Wicks, I, Roberts, LJ. Intracardiac thrombosis complicating antiphospholipid antibody syndrome. Intern Med J, 34(3), 135-7, 2004.

Montine, KS, Quinn, JF, Zhang, J, Fessel, JP, Roberts, LJ, Morrow, JD, Montine, TJ. Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases. Chem Phys Lipids, 128(1-2), 117-24, 2004.

Montuschi, P, Barnes, PJ, Roberts, LJ. Isoprostanes: markers and mediators of oxidative stress. FASEB J, 18(15), 1791-800, 2004.

Mun-Bryce, S, Roberts, LJ, Hunt, WC, Bartolo, A, Okada, Y. Acute changes in cortical excitability in the cortex contralateral to focal intracerebral hemorrhage in the swine. Brain Res, 1026(2), 218-26, 2004.

Ran, Q, Liang, H, Gu, M, Qi, W, Walter, CA, Roberts, LJ, Herman, B, Richardson, A, Van Remmen, H. Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J Biol Chem, 279(53), 55137-46, 2004.

Roberts, LJ. New drugs for rheumatoid arthritis. N Engl J Med, 351(25), 2659-61; author reply 2659-61, 2004.

Roberts, LJ, Fessel, JP. The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation. Chem Phys Lipids, 128(1-2), 173-86, 2004.

Taber, DF, Fessel, JP, Roberts, LJ. A nomenclature system for isofurans. Prostaglandins Other Lipid Mediat, 73(1-2), 47-50, 2004.

Vorster, AA, Rebello, MT, Coutts, N, Ehrenreich, L, Gama, AD, Roberts, LJ, Goliath, R, Ramesar, R, Greenberg, LJ. Arg120stop nonsense mutation in the RP2 gene: mutational hotspot and germ line mosaicism. Clin Genet, 65(1), 7-10, 2004.

Wu, T, Rifai, N, Roberts, LJ, Willett, WC, Rimm, EB. Stability of measurements of biomarkers of oxidative stress in blood over 36 hours. Cancer Epidemiol Biomarkers Prev, 13(8), 1399-402, 2004.

Yang, H, Roberts, LJ, Shi, MJ, Zhou, LC, Ballard, BR, Richardson, A, Guo, ZM. Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circ Res, 95(11), 1075-81, 2004.

Zagol-Ikapitte, I, Bernoud-Hubac, N, Amarnath, V, Roberts, LJ, Boutaud, O, Oates, JA. Characterization of bis(levuglandinyl) urea derivatives as products of the reaction between prostaglandin H2 and arginine. Biochemistry, 43(18), 5503-10, 2004.

Boutaud, Olivier, Li, Junyu, Zagol, Irene, Shipp, Elizabeth A, Davies, Sean S, Roberts, L Jackson, Oates, John A. Levuglandinyl Adducts of Proteins Are Formed via a Prostaglandin H2 Synthase-dependent Pathway after Platelet Activation. J Biol Chem, 278(19), 16926-8, 2003.

Campbell, IK, Roberts, LJ, Wicks, IP. Molecular targets in immune-mediated diseases: the case of tumour necrosis factor and rheumatoid arthritis. Immunol Cell Biol, 81(5), 354-66, 2003.

Davies, Sean S, Ju, Won-Kyu, Neufeld, Arthur H, Abran, Daniel, Chemtob, Sylvain, Roberts, L Jackson. Hydrolysis of bimatoprost (Lumigan) to its free acid by ocular tissue in vitro. J Ocul Pharmacol Ther, 19(1), 45-54, 2003.

Fessel, Joshua P, Hulette, Christine, Powell, Suzanne, Roberts, L Jackson, Zhang, Jing. Isofurans, but not F2-isoprostanes, are increased in the substantia nigra of patients with Parkinson's disease and with dementia with Lewy body disease. J Neurochem, 85(3), 645-50, 2003.

Fortepiani, Lourdes A, Zhang, Huimin, Racusen, Lorraine, Roberts, L Jackson, Reckelhoff, Jane F. Characterization of an animal model of postmenopausal hypertension in spontaneously hypertensive rats. Hypertension, 41(3 Pt 2), 640-5, 2003.

Huang, Hong, He, Zhi, Roberts, L Jackson, Salahudeen, Abdulla K. Deferoxamine reduces cold-ischemic renal injury in a syngeneic kidney transplant model. Am J Transplant, 3(12), 1531-7, 2003.

Jha, S, Roberts, LJ. Acrania. J Obstet Gynaecol, 23(1), 78, 2003.

Ran, Qitao, Van Remmen, Holly, Gu, Mingjun, Qi, Wenbo, Roberts, L Jackson, Prolla, Tomas, Richardson, Arlan. Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes. Free Radic Biol Med, 35(9), 1101-9, 2003.

Roberts, LJ, Thackray, M. Recovery intervention to manage severe pain: comparing apples with oranges. Anaesth Intensive Care, 31(6), 699-700, 2003.

Shaner, A, Eckman, T, Roberts, LJ, Fuller, T. Feasibility of a skills training approach to reduce substance dependence among individuals with schizophrenia. Psychiatr Serv, 54(9), 1287-9, 2003.

Swanson, SP, Roberts, LJ, Chapman, MD. Are anaesthetists prone to suicide? A review of rates and risk factors. Anaesth Intensive Care, 31(4), 434-45, 2003.

Willcox, Joye K, Catignani, George L, Roberts, L Jackson. Dietary flavonoids fail to suppress F(2)-isoprostane formation in vivo. Free Radic Biol Med, 34(7), 795-9, 2003.

Bernoud-Hubac, Nathalie, Roberts, L Jackson. Identification of oxidized derivatives of neuroketals. Biochemistry, 41(38), 11466-71, 2002.

Davies, Sean S, Amarnath, Ventkataraman, Montine, Kathleen S, Bernoud-Hubac, Nathalie, Boutaud, Olivier, Montine, Thomas J, Roberts, L Jackson. Effects of reactive gamma-ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function. FASEB J, 16(7), 715-7, 2002.

Fam, Samuel S, Murphey, Laine J, Terry, Erin S, Zackert, William E, Chen, Yan, Gao, Ling, Pandalai, Saurabh, Milne, Ginger L, Roberts, L Jackson, Porter, Ned A, Montine, Thomas J, Morrow, Jason D. Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid. J Biol Chem, 277(39), 36076-84, 2002.

Fessel, Joshua P, Porter, Ned A, Moore, Kevin P, Sheller, James R, Roberts, L Jackson. Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension. Proc Natl Acad Sci U S A, 99(26), 16713-8, 2002. PMCID:139209

Hubatsch, Ina, Mannervik, Bengt, Gao, Ling, Roberts, L Jackson, Chen, Yan, Morrow, Jason D. The cyclopentenone product of lipid peroxidation, 15-A(2t)-isoprostane (8-isoprostaglandin A(2)), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4. Chem Res Toxicol, 15(9), 1114-8, 2002.

Ikizler, T A, Morrow, J D, Roberts, L J, Evanson, J A, Becker, B, Hakim, R M, Shyr, Y, Himmelfarb, J. Plasma F2-isoprostane levels are elevated in chronic hemodialysis patients. Clin Nephrol, 58(3), 190-7, 2002.

Jha, S, Haldar, MK, Roberts, LJ. Primary ovarian pregnancy with an intrauterine contraceptive device in situ. J Obstet Gynaecol, 22(1), 104-5, 2002.

Meng, Shumei, Roberts, L Jackson, Cason, Garrick W, Curry, Travis S, Manning, R Davis. Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats. Am J Physiol Regul Integr Comp Physiol, 283(3), R732-8, 2002.

Milatovic, Dejan, Zhang, Yueli, Olson, Sandra J, Montine, Kathleen S, Roberts, L Jackson, Morrow, Jason D, Montine, Thomas J, Dermody, Terence S, Valyi-Nagy, Tibor. Herpes simplex virus type 1 encephalitis is associated with elevated levels of F2-isoprostanes and F4-neuroprostanes. J Neurovirol, 8(4), 295-305, 2002.

Miller, Elizabeth T, Neal, Dan J, Roberts, Lisa J, Baer, John S, Cressler, Sally O, Metrik, Jane, Marlatt, G Alan. Test-retest reliability of alcohol measures: is there a difference between internet-based assessment and traditional methods?. Psychol Addict Behav, 16(1), 56-63, 2002.

Montine, Thomas J, Neely, M Diana, Quinn, Joseph F, Beal, M Flint, Markesbery, William R, Roberts, L Jackson, Morrow, Jason D. Lipid peroxidation in aging brain and Alzheimer's disease. Free Radic Biol Med, 33(5), 620-6, 2002.

Montine, Thomas J, Quinn, Joseph F, Milatovic, Dejan, Silbert, Lisa C, Dang, Theresa, Sanchez, Stephanie, Terry, Erin, Roberts, L Jackson, Kaye, Jeffrey A, Morrow, Jason D. Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease. Ann Neurol, 52(2), 175-9, 2002.

Morrow, Jason D, Roberts, L Jackson. Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress. Methods Mol Biol, 186, 57-66, 2002.

Morrow, Jason D, Roberts, L Jackson. The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease. Am J Respir Crit Care Med, 166(12 Pt 2), S25-30, 2002.

Roberts, L J, Khursandi, D C S. Career choice influences in Australian anaesthetists. Anaesth Intensive Care, 30(3), 355-9, 2002.

Roberts, L Jackson, Morrow, J D. Products of the isoprostane pathway: unique bioactive compounds and markers of lipid peroxidation. Cell Mol Life Sci, 59(5), 808-20, 2002.

Roberts, Lindy J, Finch, Phillip M, Pullan, Peter T, Bhagat, Chotoo I, Price, Leanne M. Sex hormone suppression by intrathecal opioids: a prospective study. Clin J Pain, 18(3), 144-8, 2002.

Sasaki, Diane M, Yuan, Ying, Gikas, Katherine, Kanai, Kazuo, Taber, Douglass, Morrow, Jason D, Roberts, L Jackson, Callewaert, Denis M. Enzyme immunoassays for 15-F2T isoprostane-M, an urinary biomarker for oxidant stress. Adv Exp Med Biol, 507, 537-41, 2002.

Vanharanta, Meri, Voutilainen, Sari, Nurmi, Tarja, Kaikkonen, Jari, Roberts, L Jackson, Morrow, Jason D, Adlercreutz, Herman, Salonen, Jukka T. Association between low serum enterolactone and increased plasma F2-isoprostanes, a measure of lipid peroxidation. Atherosclerosis, 160(2), 465-9, 2002.

Wells, N, Roberts, L, Medlin, LC. Issues related to staff retention and turnover. Semin Nurse Manag, 10(3), 171-9, 2002.

Youssef, Jihan, Davis, Alan, Roberts, L Jackson, Swift, Larry L, Morrow, Jason D, Badr, Mostafa. Pantothenic acid: an organ-specific pro-oxidant vitamin. Brain and liver neuroprostane levels in rats fed a pantothenic acid-deficient diet. Adv Exp Med Biol, 507, 551-5, 2002.

Barany P, Stenvinkel P, Ottosson-Seeberger, Alvestrand A, Morrow JD, Roberts LJ, II, and Salahudeen A. Effect of 6-weeks of vitamin E administration on renal hemodynamic alterations following a single dose of Neoral in healthy volunteers. Nephrol. Dial. Transplant., 16, 580-584, 2001.

Bernoud-Hubac N, Davies SS, Boutaud O, Montine TJ, and Roberts LJ, II. Formation of highly reactive -ketoaldehydes (neuroketals) as products of the neuroprostane pathway. J. Biol. Chem, 276, 30964-30970, 2001.

Bernoud-Hubac, N, Davies, S S, Boutaud, O, Montine, T J, Roberts, L J. Formation of highly reactive gamma-ketoaldehydes (neuroketals) as products of the neuroprostane pathway. J Biol Chem, 276(33), 30964-70, 2001.

Boutand O, Brame CJ, Chaurand, P, Scott JL, Rowlinson SE, Crews BC, Chuan J, Marnett LJ, Roberts LJ, II, and Oates, JA. Characterization of the adducts of prostaglandin H synthases that are derived from oxygenation of arachidonic acid. Biochemistry, 40, 6948-6955, 2001.

Boutaud, O, Brame, C J, Chaurand, P, Li, J, Rowlinson, S W, Crews, B C, Ji, C, Marnett, L J, Caprioli, R M, Roberts, L J, Oates, J A. Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid. Biochemistry, 40(23), 6948-55, 2001.

Boutaud, O, Li, J, Chaurand, P, Brame, C J, Marnett, L J, Roberts, L J, Oates, J A. Oxygenation of arachidonic acid by cyclooxygenases generates reactive intermediates that form adducts with proteins. Adv Exp Med Biol, 500, 133-7, 2001.

Dworski, R, Murray, JJ, Roberts, LJ, II, Oates, JA, Morrow, JD, Hartert, T, and Sheller, JR. Assment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2 ). Clin. Exp. Allergy, 31, 387-390, 2001.

Dworski, R, Roberts, L J, Murray, J J, Morrow, J D, Hartert, T V, Sheller, J R. Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha). Clin Exp Allergy, 31(3), 387-90, 2001.

Hou X, Roberts LJ, II, Morrow JD, Taber DF, Kanai K, Gobeil F, Varma DR, and Chemtob S. 2,3-Dinor-5,6-dihydro-15-F2t-isoprostane is a bioactive isoprostane metabolite. Am. J. Physiol. Regulatory Comp. Physiol. , 281, R391-R400, 2001.

Hou, X, Roberts, L J, Taber, D F, Morrow, J D, Kanai, K, Gobeil, F, Beauchamp, M H, Bernier, S G, Lepage, G, Varma, D R, Chemtob, S. 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. Am J Physiol Regul Integr Comp Physiol, 281(2), R391-400, 2001.

Kaikkonen, J, Porkkala-Sarataho, E, Morrow, J D, Roberts, L J, Nyyss??nen, K, Salonen, R, Tuomainen, T P, Ristonmaa, U, Poulsen, H E, Salonen, J T. Supplementation with vitamin E but not with vitamin C lowers lipid peroxidation in vivo in mildly hypercholesterolemic men. Free Radic Res, 35(6), 967-78, 2001.

Lahaie O, Hardy P, Hou X, Hassessian H, Asselin P, Lachapelle P, Almazan G, Varma DR, Roberts LJ, II, and Chemtob S. Cytotoxic effects of thromboxane on neurovascular endothelial cells: Possible role in ischemic neuropathies. J. Appl. Physiol, 90, 2279-2288, 2001.

Marathe GK, Harrison KA, Roberts LJ, II, Morrow JD, Murphy RC, Tjoelker LW, Prescott SM, Zimmerman GA, and McIntyre TM. Identification of platelet activating factor as the inflammatory lipid mediator in CCL4-induced rat liver damage. J. Lip. Res., 42, 587-596, 2001.

Marathe, G K, Harrison, K A, Roberts, L J, Morrow, J D, Murphy, R C, Tjoelker, L W, Prescott, S M, Zimmerman, G A, McIntyre, T M. Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. J Lipid Res, 42(4), 587-96, 2001.

Patel, M, Liang, L P, Roberts, L J. Enhanced hippocampal F2-isoprostane formation following kainate-induced seizures. J Neurochem, 79(5), 1065-9, 2001.

Reich EE, Markesbery WR, Roberts LJ, II, Swift LL, Morrow JD, and Montine, TJ. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Am. J. Pathol., 158, 293-297, 2001.

Reich EE, Montine KS, Gross M, Roberts LJ, II, Swift LL, Morrow JD, and Montine TJ. Interactions between apolipoprotein E gene and dietary -tocopherol influence cerebral oxidative damage in aged mice. J. Neuroscience, 21, 59993-5999, 2001.

Reich, E E, Markesbery, W R, Roberts, L J, Swift, L L, Morrow, J D, Montine, T J. Quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Adv Exp Med Biol, 500, 253-6, 2001.

Reich, E E, Markesbery, W R, Roberts, L J, Swift, L L, Morrow, J D, Montine, T J. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Am J Pathol, 158(1), 293-7, 2001. PMCID:1850257

Reich, E E, Montine, K S, Gross, M D, Roberts, L J, Swift, L L, Morrow, J D, Montine, T J. Interactions between apolipoprotein E gene and dietary alpha-tocopherol influence cerebral oxidative damage in aged mice. J Neurosci, 21(16), 5993-9, 2001.

Roberts, L J, Finch, P M, Goucke, C R, Price, L M. Outcome of intrathecal opioids in chronic non-cancer pain. Eur J Pain, 5(4), 353-61, 2001.

Roberts, L J, Goucke, C R. Retro-orbital tumour--an uncommon cause of headache in pregnancy. Anaesth Intensive Care, 29(3), 276-80, 2001.

Roberts, L J, Reckelhoff, J F. Measurement of F(2)-isoprostanes unveils profound oxidative stress in aged rats. Biochem Biophys Res Commun, 287(1), 254-6, 2001.

Salahudeen, A K, Oliver, B, Bower, J D, Roberts, L J. Increase in plasma esterified F2-isoprostanes following intravenous iron infusion in patients on hemodialysis. Kidney Int, 60(4), 1525-31, 2001.

Youssef J, Birnbaum L, Roberts, LJ, II, Swift LL, Morrow J, and Badr M. Brain oxidative stress, senescence and death. Isoprostanes and neuroprostanes: novel markers and new theories. Antioxidants and Free Radicals in Health and Disease. J Marway, A Kanthasamy, Eds., Prominent Press, Scotsdale, , pp. 261-278, 2001.

Finch, P M, Roberts, L J, Price, L, Hadlow, N C, Pullan, P T. Hypogonadism in patients treated with intrathecal morphine. Clin J Pain, 16(3), 251-4, 2000.

Graf, B A, Nazarenko, D A, Borrello, M A, Roberts, L J, Morrow, J D, Phipps, R P. Proinflammatory signals upregulate COX-2 and increase PGE2 production in biphenotypic B/macrophage cells. Ann N Y Acad Sci, 905, 294-6, 2000.

Hou X, Gobeil F, Peri K, Speranza G., Marrache M, Lachapelle P, Roberts LJ, II, Varma DR, and Chemtob S. Differential induction of vasoconstriction and thromboxane formation in immature pig periventricular brain microvessels by 15-F2t-isoprostane (8-iso-prostaglandin F2 ). Stroke, 31, 516-525, 2000.

Montine, T J, Shinobu, L, Montine, K S, Roberts, L J, Kowall, N W, Beal, M F, Morrow, J D. No difference in plasma or urinary F2-isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls. Ann Neurol, 48(6), 950, 2000.

O'Byrne, S, Forte, P, Roberts, L J, Morrow, J D, Johnston, A, Angg?Yrd, E, Leslie, R D, Benjamin, N. Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion. Diabetes, 49(5), 857-62, 2000.

O'Byrne, S, Forte, P, Roberts, LJ, II, Morrow, JD, Johnston, A, Angaard. E, Leslie, D, and Benjamin, N. Nitric oxide synthesis and isoprostane production in subjects with Type-1 diabetes and normal urinary albumin excretion. Diabetes , 49, 857-862, 2000.

Phipps, R P, Pollock, S J, Kaur, K, Kaufman, J, Borrello, M A, Graf, B A, Nazarenko, D, Roberts, L J, Morrow, J D, Palis, J, Ryan, D J, Bennett, J M. Expression of cyclooxygenase-2 and prostaglandins by B-1 cells and B-CLL cells. Curr Top Microbiol Immunol, 252, 293-300, 2000.

Reckelhoff JF, Zhang H, Srivastava K, Roberts LJ, II, Morrow JD, and Romero JC. Subpressor doses of angiotensin II increase F2-isoprostanes and peroxynitrite in rats. Hypertension, 35, 476-479, 2000.

Reckelhoff, J F, Zhang, H, Srivastava, K, Roberts, L J, Morrow, J D, Romero, J C. Subpressor doses of angiotensin II increase plasma F(2)-isoprostanes in rats. Hypertension, 35(1 Pt 2), 476-9, 2000.

Reich EE, Zackert WE, Brame CJ, Chen Y, Roberts LJ, II, Hachey DL, Montine TJ, and Morrow JD. Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. Biochemistry, 39, 2376-2383, 2000.

Reich, E E, Zackert, W E, Brame, C J, Chen, Y, Roberts, L J, Hachey, D L, Montine, T J, Morrow, J D. Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. Biochemistry, 39(9), 2376-83, 2000.

Roberts, L J, Foote, S J, Handman, E. A new standard for the assessment of disease progression in murine cutaneous leishmaniasis. Parasite Immunol, 22(5), 231-7, 2000.

Roberts, L J, Handman, E, Foote, S J. Science, medicine, and the future: Leishmaniasis. BMJ, 321(7264), 801-4, 2000. PMCID:1118618

Roberts, L J, Morrow, J D. Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. Free Radic Biol Med, 28(4), 505-13, 2000.

Roberts, L J, Neal, D J, Kivlahan, D R, Baer, J S, Marlatt, G A. Individual drinking changes following a brief intervention among college students: clinical significance in an indicated preventive context. J Consult Clin Psychol, 68(3), 500-5, 2000.

Roberts, LJ, II, and Morrow JD. Measurement of F2-isoprostanes as an index of oxidative stress in vivo. Free Rad. Biol. Med, 28, 505-513, 2000.

Walsh SW, Vaughan JE, Wang Y, and Roberts LJ, II. Placental isoprostane is significantly increased in preeclampsia. FASEB J., 14, 1289-1296, 2000.

Walsh, S W, Vaughan, J E, Wang, Y, Roberts, L J. Placental isoprostane is significantly increased in preeclampsia. FASEB J, 14(10), 1289-96, 2000.

Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ, II, Wynshaw-Boris A, and Levine RL. Loss of the ataxia-telangiectasia gene products causes oxidative damage in target organs. Proc. Natl. Acad. Sci. USA, 96, 9915-9919, 1999.

Barlow, C, Dennery, P A, Shigenaga, M K, Smith, M A, Morrow, J D, Roberts, L J, Wynshaw-Boris, A, Levine, R L. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci U S A, 96(17), 9915-9, 1999. PMCID:22310

Boutand, O, Brame, CJ, Salomon, RG, Roberts, LJ, II, and Oates, JA. Characterization of lysyl adducts formed from prostaglandin H2 via the levuglandin pathway. Biochemistry, 38, 9389-9386, 1999.

Boutaud, O, Brame, C J, Salomon, R G, Roberts, L J, Oates, J A. Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway. Biochemistry, 38(29), 9389-96, 1999.

Brame, C J, Salomon, R G, Morrow, J D, Roberts, L J. Identification of extremely reactive gamma-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts. J Biol Chem, 274(19), 13139-46, 1999.

Chen Y, Zackert WE, Roberts LJ II, and Morrow JD. Evidence for the formation of a novel cyclopentenone isoprostane, 15-A2t-IsoP (8-iso-prostaglandin A2. Vivo. Biochim. Biophys. Acta, 1436, 550-556, 1999.

Chen, Y, Morrow, J D, Roberts, L J. Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway. J Biol Chem, 274(16), 10863-8, 1999.

Chen, Y, Morrow, JD, and Roberts, LJ, II. Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway. J. Biol. Chem., 274, 10863-10868, 1999.

Chen, Y, Zackert, W E, Roberts, L J, Morrow, J D. Evidence for the formation of a novel cyclopentenone isoprostane, 15-A2t-isoprostane (8-iso-prostaglandin A2) in vivo. Biochim Biophys Acta, 1436(3), 550-6, 1999.

Choong, K Y, Roberts, L J. Molluscum contagiosum, swimming and bathing: a clinical analysis. Australas J Dermatol, 40(2), 89-92, 1999.

Dworski R, Murray JJ, Roberts, LJ, II, Oates, JA, Morrow, JD, Fisher, L., and Sheller, JR. Allergen-induced synthesis of F2-isoprostanes in atopic asthmatics: evidence for oxidative stress. Am. J. Resp. Crit. Care Med., 160, 1947-1951, 1999.

Dworski, R, Murray, J J, Roberts, L J, Oates, J A, Morrow, J D, Fisher, L, Sheller, J R. Allergen-induced synthesis of F(2)-isoprostanes in atopic asthmatics. Evidence for oxidant stress. Am J Respir Crit Care Med, 160(6), 1947-51, 1999.

Graf, B A, Nazarenko, D A, Borrello, M A, Roberts, L J, Morrow, J D, Palis, J, Phipps, R P. Biphenotypic B/macrophage cells express COX-1 and up-regulate COX-2 expression and prostaglandin E(2) production in response to pro-inflammatory signals. Eur J Immunol, 29(11), 3793-803, 1999.

Holt, S, Reeder, B, Wilson, M, Harvey, S, Morrow, J D, Roberts, L J, Moore, K. Increased lipid peroxidation in patients with rhabdomyolysis. Lancet, 353(9160), 1241, 1999.

Holt, S, Reeder, B, Wilson, M, Harvey, S, Morrow, JD, Roberts, LJ, II, and Moore, K. Increased lipid peroxidation in patients with rhabdomyolysis. Lancet, 353, 1241, 1999.

Jacobson, NS, Roberts, LJ, Berns, SB, McGlinchey, JB. Methods for defining and determining the clinical significance of treatment effects: description, application, and alternatives. J Consult Clin Psychol, 67(3), 300-7, 1999.

Liu T, Stern A, Roberts LJ, II, and Morrow JD. The isoprostanes: novel prostaglandin-like products of the free radical-catalyzed peroxidation of arachidonic acid. J. Biomed. Sci, 6, 226-235, 1999.

Liu, T, Stern, A, Roberts, L J, Morrow, J D. The isoprostanes: novel prostaglandin-like products of the free radical-catalyzed peroxidation of arachidonic acid. J Biomed Sci, 6(4), 226-35, 1999.

Mills, J L, DerSimonian, R, Raymond, E, Morrow, J D, Roberts, L J, Clemens, J D, Hauth, J C, Catalano, P, Sibai, B, Curet, L B, Levine, R J. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. JAMA, 282(4), 356-62, 1999.

Montine TJ, Markesbery WR, Zackert W, Sanchez SC, Roberts LJ, II, and Morrow JD. The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APE Genotype in Alzheimer's disease patients. Am. J. Pathol., 155, 863-868, 1999.

Montine, T J, Beal, M F, Cudkowicz, M E, O'Donnell, H, Margolin, R A, McFarland, L, Bachrach, A F, Zackert, W E, Roberts, L J, Morrow, J D. Increased CSF F2-isoprostane concentration in probable AD. Neurology, 52(3), 562-5, 1999.

Montine, T J, Beal, M F, Robertson, D, Cudkowicz, M E, Biaggioni, I, O'Donnell, H, Zackert, W E, Roberts, L J, Morrow, J D. Cerebrospinal fluid F2-isoprostanes are elevated in Huntington's disease. Neurology, 52(5), 1104-5, 1999.

Montine, T J, Markesbery, W R, Zackert, W, Sanchez, S C, Roberts, L J, Morrow, J D. The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients. Am J Pathol, 155(3), 863-8, 1999. PMCID:1866881

Montine, T J, Montine, K S, Olson, S J, Graham, D G, Roberts, L J, Morrow, J D, Linton, M F, Fazio, S, Swift, L L. Increased cerebral cortical lipid peroxidation and abnormal phospholipids in aged homozygous apoE-deficient C57BL/6J mice. Exp Neurol, 158(1), 234-41, 1999.

Montine, T J, Sidell, K R, Crews, B C, Markesbery, W R, Marnett, L J, Roberts, L J, Morrow, J D. Elevated CSF prostaglandin E2 levels in patients with probable AD. Neurology, 53(7), 1495-8, 1999.

Montine, TJ, Beal, MF, Cudkowicz, MD, O'Donnel, H, Margolin, RA, McFarland, L., Cachrach, AF, Zackert, WE, Roberts, LJ, II, and Morrow, JD. Increased CSF F2-isoprostane concentration in probable AD. Neurology, 52, 562-565, 1999.

Montine, TJ, Beal, MF, Roberts, D, Cudkowicz, ME, Brown, RH, O'Donnel, H, Zackert, WE, Roberts, LJ, II, and Morrow, JD. Cerebrospinal levels of F2-isoprostanes, specific markers of lipid peroxidation, are elevated in Huntington's disease patients. Neurology, 52, 1104-1105, 1999.

Montine, TJ, Montine, KS, Olson, SJ, Graham, DG, Roberts, LJ, II, Morrow, JD, Swift, LL, Linton, M, and Fazio, S. Increased cerebral cortical products of lipid peroxidation (Neuroprostanes) and abnormal phospholipids in aged homozygous ApoE deficient C57BL/Cj mice. Exp. Neurol., 158, 234-241, 1999.

Montine, TJ, Sidell, KR, Crews, BC, Zackert, WE, Markesbery, WR, Marnett, Roberts, LJ, II, and Morrow, JD. Elevated CSF prostaglandin E2 levels in patients with probable AD. Neurology, 53, 1495-1498, 1999.

Morrow JD, Zackert WE, Yang JP, Kurhts EH, Callewaert D, Kanai, K, Taber DF, Moore, KP, Oates JA, and Roberts LJ II. Quantification of the major urinary metabolite of the isoprostane 15-F2t-isoprostane (8-iso-PGF2 ) by stable isotope dilution mass spectrometric assay. Anal. Biochem., 269, 326-331, 1999.

Morrow, J D, Chen, Y, Brame, C J, Yang, J, Sanchez, S C, Xu, J, Zackert, W E, Awad, J A, Roberts, L J. The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. Drug Metab Rev, 31(1), 117-39, 1999.

Morrow, J D, Oates, J A, Roberts, L J, Zackert, W E, Mitchell, T A, Lazarus, G, Guzzo, C. Increased formation of thromboxane in vivo in humans with mastocytosis. J Invest Dermatol, 113(1), 93-7, 1999.

Morrow, J D, Roberts, L J. Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. Methods Enzymol, 300, 3-12, 1999.

Morrow, J D, Tapper, A R, Zackert, W E, Yang, J, Sanchez, S C, Montine, T J, Roberts, L J. Formation of novel isoprostane-like compounds from docosahexaenoic acid. Adv Exp Med Biol, 469, 343-7, 1999.

Morrow, J D, Zackert, W E, Yang, J P, Kurhts, E H, Callewaert, D, Dworski, R, Kanai, K, Taber, D, Moore, K, Oates, J A, Roberts, L J. Quantification of the major urinary metabolite of 15-F2t-isoprostane (8-iso-PGF2alpha) by a stable isotope dilution mass spectrometric assay. Anal Biochem, 269(2), 326-31, 1999.

Morrow, JD, Chen, Y, Brame, CJ, Yang, J, Sanchez, SC, Xu, J, Zackert, WE, and Roberts, LJ, II. The isoprostanes: Unique prostaglandin-like products of free radical-catalyzed lipid peroxidation. Drug Metab. Rev., 31, 117-139, 1999.

Reckelhof JF, Henntington, BS, Kanjii V, Racusen LC, Schmidt SD, Yan J, Morrow JD, Roberts LJ II, and Salahudeen AK. Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats. Am. J. Hypertenison, 12, 492-498, 1999.

Reckelhoff, J F, Hennington, B S, Kanji, V, Racusen, L C, Schmidt, A M, Yan, S D, Morrow, J, Roberts, L J, Salahudeen, A K. Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats. Am J Hypertens, 12(5), 492-8, 1999.

Roberts, L J. Delegation for the novice nurse. Fla Nurse, 47(3), 9, 1999.

Roberts, L J, Baldwin, T M, Speed, T P, Handman, E, Foote, S J. Chromosomes X, 9, and the H2 locus interact epistatically to control Leishmania major infection. Eur J Immunol, 29(9), 3047-50, 1999.

Roberts, L J, Brame, C J, Chen, Y, Morrow, J D. Novel eicosanoids. Isoprostanes and related compounds. Methods Mol Biol, 120, 257-85, 1999.

Roberts, L J, Brame, C J, Chen, Y, Morrow, J D, Salomon, R G. Formation of reactive products of the isoprostane pathway: isolevuglandins and cyclopentenone isoprostanes. Adv Exp Med Biol, 469, 335-41, 1999.

Roberts, L J, Salem, D, Rappaport, J, Toro, P A, Luke, D A, Seidman, E. Giving and receiving help: interpersonal transactions in mutual-help meetings and psychosocial adjustment of members. Am J Community Psychol, 27(6), 841-68, 1999.

Roberts, L J, Salomon, R G, Morrow, J D, Brame, C J. New developments in the isoprostane pathway: identification of novel highly reactive gamma-ketoaldehydes (isolevuglandins) and characterization of their protein adducts. FASEB J, 13(10), 1157-68, 1999.

Roberts, LJ, II, Brame, CJ, Chen, Y, and Morrow, JD. Novel eicosanoids: Isoprostanes and related compounds. Methods in Molecular Biology, vol. 120, (E. A. Lianos, ed) Humana Press, Totowa, NJ, , 257-285, 1999.

Roberts, LJ, II, Salomon, RG, Morrow, JD, and Brame, CJ. New developments in the isoprostane pathway: Identification of novel highly reactive -ketoaldehydes (isolevuglandins) and characterization of their protein adducts. FASEB J, 13, 1157-1168, 1999.

Roberts, LJ, II, and Morrow, JD. Formation of novel isoprostane-like compounds by free radical catalyzed peroxidation of docosahexaenoic acid. Essential Fatty Acids and Eicosanoids. RA Riemersma, RA Armstrong, RW Kelly, R Wilson, eds., AOCS press, Champaign, Ill, , pp. 197-199, 1999.

Roberts, LJ, II, and Morrow, JD. Isoprostanes as markers of lipid peroxidation in atherosclerosis. Molecular Biology of Inflammation. CN Serhan, PA Ward, eds., Humana Press, , pp 141-163, 1999.

Salahudeen A, Nawaz M, Poovala V, Kanjii V, Wang C, Morrow JD, and Roberts LJ II. Cold induces time-dependent F2-isoprostane formation in renal tubular cells and rat kidneys stored in University of Wisconsin solution: Implications for immediate post-transplant renal vasoconstriction. Kidney Internat, 55, 1759-1762, 1999.

Salomon, R G, Sha, W, Brame, C, Kaur, K, Subbanagounder, G, O'Neil, J, Hoff, H F, Roberts, L J. Protein adducts of iso[4]levuglandin E2, a product of the isoprostane pathway, in oxidized low density lipoprotein. J Biol Chem, 274(29), 20271-80, 1999.

Salomon, RG, Sha W, Brame, C, Kaur, K, Subbanagounder, G, O'Neil, J, Hoff, HF, and Roberts, LJ, II. Protein adducts of isolevuglandin E2 in oxidized low density lipoprotein. J. Biol. Chem., 274, 20271-20280, 1999.

Valyi-Nagy, T, Sidell, K R, Marnett, L J, Roberts, L J, Dermody, T S, Morrow, J D, Montine, T J. Divergence of brain prostaglandin H synthase activity and oxidative damage in mice with encephalitis. J Neuropathol Exp Neurol, 58(12), 1269-75, 1999.

Valyi-Nagy, T, Sidell, KR, Marnett, LJ, Roberts, LJ, II, Dermody, TS, Morrow, JD, and Montine, TJ. Divergence of brain prostaglandin H synthase activity and oxidative damage in mice with encephalitis. J. Neuropath. Exp. Neurol., 58, 1269-1275, 1999.

Van der Veen, R, and Roberts, LJ, II. Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids. J. Neuroimmunol, 95, 1-7, 1999.

Voutilainen S, Morrow, JD, Roberts, LJ, II, Alfthan, G, Alho, H, Nyyssonen, K, and Salonen, JT. Enhanced in vivo lipid peoxidation at elevated plasma homocysteine levels. Ateriosclerosis Thromb. Vasc. Biol., 19, 1263-1266, 1999.

Voutilainen, S, Morrow, J D, Roberts, L J, Alfthan, G, Alho, H, Nyyss??nen, K, Salonen, J T. Enhanced in vivo lipid peroxidation at elevated plasma total homocysteine levels. Arterioscler Thromb Vasc Biol, 19(5), 1263-6, 1999.

van der Veen, R C, Roberts, L J. Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids. J Neuroimmunol, 95(1-2), 1-7, 1999.

Roberts, LJ, II, Montine, TJ, Markesbery, WR, Tapper, AR, Hardy P, Chemtob, C, Dettbarn, WD, and Morrow, JD.. Formation of isoprostane- like compounds (Neuroprostanes) in vivo from docosahexaenoic acid. J. Biol. Chem., 273, 13605-13612, 1998.

Barrett, R S, Neal, R J, Roberts, L J. The dynamic loading response of surfaces encountered in beach running. J Sci Med Sport, 1(1), 1-11, 1998.

Bolton, P G, Mira, M, Roberts, L J, Usher, H E. Is health care card status related to consultation time?. Med J Aust, 168(10), 527-8, 1998.

Kadiiska, M B, Morrow, J D, Awad, J A, Roberts, L J, Mason, R P. Identification of free radical formation and F2-isoprostanes in vivo by acute Cr(VI) poisoning. Chem Res Toxicol, 11(12), 1516-20, 1998.

Kadiiska, MB, Morrow, JD, Awad, JA, Roberts, LJ, II, and Mason, RP. Enhanced formation of free radicals and F2-isoprostanes in vivo by acute Cr (VI) poisoning. Chem. Res. Toxicol., 11, 1516-1520, 1998.

Kanji, V, Racusen L, Schmidt, AM, Yan, SD, Morrow, JD, Roberts, LJ, II, and Salahudeen, AK. Vitamin E ameliorates enhanced renal lipid peroxidation and accumulation of F2-isoprostanes in aging kidneys. Am. J. Physiol., 274, R767-774, 1998.

Lahaie, I, Hardy, P, Hou, X, Hassessian, H, Asselin, P, Lachapelle, P, Almazan, G, Varma, DR, Morrow, J.D, Roberts, LJ, II, and Chemtob, S. A novel mechanism for the vasoconstrictor action of 8-iso-prostaglandin F2 on retinal blood vessels. Am. J. Physiol.274 (Regulatory Integrative Comp. Physiol, 4(3), R1406-R1416, 1998.

Lahaie, I, Hardy, P, Hou, X, Hass??ssian, H, Asselin, P, Lachapelle, P, Almazan, G, Varma, D R, Morrow, J D, Roberts, L J, Chemtob, S. A novel mechanism for vasoconstrictor action of 8-isoprostaglandin F2 alpha on retinal vessels. Am J Physiol, 274(5 Pt 2), R1406-16, 1998.

Leonard, K E, Roberts, L J. The effects of alcohol on the marital interactions of aggressive and nonaggressive husbands and their wives. J Abnorm Psychol, 107(4), 602-15, 1998.

Montine, T J, Markesbery, W R, Morrow, J D, Roberts, L J. Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease. Ann Neurol, 44(3), 410-3, 1998.

Montine, TJ, Markesbery, WR, Morrow, JD, and Roberts, LJ, II. Cerebrospinal fluid F2-isoprostane levels are increased in patients with Alzheimer's disease. Annals Neurol, 44, 410-413, 1998.

Moore K, Patel, R, Darley-Usmar, V, Holt, S, Zackert WE, Clozel, M, Anand, R, Wilson, M, Harvey, S, Morrow, JD, and Roberts, LJ, II. A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. J. Biol. Chem., 273, 31731-31737, 1998.

Moore, K P, Holt, S G, Patel, R P, Svistunenko, D A, Zackert, W, Goodier, D, Reeder, B J, Clozel, M, Anand, R, Cooper, C E, Morrow, J D, Wilson, M T, Darley-Usmar, V, Roberts, L J. A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. J Biol Chem, 273(48), 31731-7, 1998.

Moore, K, Roberts, L J. Measurement of lipid peroxidation. Free Radic Res, 28(6), 659-71, 1998.

Moore, K, and Roberts, LJ, II. Measurement of lipid peroxidation. Free Rad. Res., 28, 659-671, 1998.

Morrow, J D, Roberts, L J, Daniel, V C, Awad, J A, Mirochnitchenko, O, Swift, L L, Burk, R F. Comparison of formation of D2/E2-isoprostanes and F2-isoprostanes in vitro and in vivo--effects of oxygen tension and glutathione. Arch Biochem Biophys, 353(1), 160-71, 1998.

Morrow, J D, Scruggs, J, Chen, Y, Zackert, W E, Roberts, L J. Evidence that the E2-isoprostane, 15-E2t-isoprostane (8-iso-prostaglandin E2) is formed in vivo. J Lipid Res, 39(8), 1589-93, 1998.

Morrow, JD, Chen, Y, Zackert, WE, and Roberts, LJ, II. The isoprostanes: recent advances. Biological Oxidants and Antioxidants: Molecular Mechanisms and Health Effects. L. Packer, ed., AOCS, , pp.72-78, 1998.

Morrow, JD, Roberts, LJ, II, Daniel, VC, Mirotchnechenko, O, Swift, L., and Burk, RF. Comparison of the formation of D2/E2-Isoprostanes to F2-isoprostanes in vitro and in vivo: Effect of oxygen tension and glutathione. Arch. Biochem. Biophys, 353, 160-171, 1998.

Morrow, JD, Scruggs, J, Chen, Y, Zackert, WE, and Roberts, LJ, II. Evidence that the E2-isoprostane, 15-E2t-isoprostane (8-isoprostaglandin E2) is formed in vivo. J.Lip.Res, 39, 1589-1593, 1998.

Morrow, JD, and Roberts, LJ, II. Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. Methods Enzymol., 300, 3-12, 1998.

Reckelhoff, J F, Kanji, V, Racusen, L C, Schmidt, A M, Yan, S D, Marrow, J, Roberts, L J, Salahudeen, A K. Vitamin E ameliorates enhanced renal lipid peroxidation and accumulation of F2-isoprostanes in aging kidneys. Am J Physiol, 274(3 Pt 2), R767-74, 1998.

Roberts, L J, Montine, T J, Markesbery, W R, Tapper, A R, Hardy, P, Chemtob, S, Dettbarn, W D, Morrow, J D. Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid. J Biol Chem, 273(22), 13605-12, 1998.

Salahudeen, A, Wilson, P, Pande, R, Poovala, V, Kanji, V, Ansari, N, Morrow, JD, and Roberts, LJ, II. Cisplatin induces N-acetyl cysteine suppressible F2-isoprostane production and injury in renal tubular epithelial cells. J. Am. Soc. Nephrol., 9, 1448-1455, 1998.

Salahudeen, AK, Reckelhoff, JF, Morrow, JD, Roberts, LJ. F2-isoprostanes and the kidney. Drug News Perspect, 11(5), 287-90, 1998.

Salahudeen, AK, Reckelhoff, JF, Morrow, JD, and Roberts, LJ, II. F2- isoprostanes and the kidney. Drug News & Perspectives, 11, 287-290, 1998.

Shaner, A, Roberts, L J, Eckman, T A, Racenstein, J M, Tucker, D E, Tsuang, J W, Mintz, J. Sources of diagnostic uncertainty for chronically psychotic cocaine abusers. Psychiatr Serv, 49(5), 684-90, 1998.

Berger, T M, Polidori, M C, Dabbagh, A, Evans, P J, Halliwell, B, Morrow, J D, Roberts, L J, Frei, B. Antioxidant activity of vitamin C in iron-overloaded human plasma. J Biol Chem, 272(25), 15656-60, 1997.

Berger, TM, Polidori, MC, Dabbagh, A, Evans, PJ, Halliwell, B, Morrow, JD, and Roberts, LJ, II, Avery, ME, and Frei, B. Antioxidant activity of vitamin C in iron-overloaded human plasma. J. Biol. Chem, 25, 15656-15660, 1997.

DuBois, R, Tsujii, M, Morrow, J, Awad, J, Roberts, L, Bishop, P. Eicosanoid production and growth regulation in rat intestinal epithelial cells. Adv Exp Med Biol, 400A, 487-93, 1997.

Garabedian, E M, Roberts, L J, McNevin, M S, Gordon, J I. Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice. J Biol Chem, 272(38), 23729-40, 1997.

Gniwotta, C, Morrow, J D, Roberts, L J, K??hn, H. Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol, 17(11), 3236-41, 1997.

Gniwotta, C, Morrow, JD, Roberts, LJ, II, and Kuhn, H. Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. J. Arteriosclerosis Thromb. Vasc. Biol., 17, 236-3241, 1997.

Lynch, S M, Frei, B, Morrow, J D, Roberts, L J, Xu, A, Jackson, T, Reyna, R, Klevay, L M, Vita, J A, Keaney, J F. Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. Arterioscler Thromb Vasc Biol, 17(11), 2975-81, 1997.

Lynch, SM, Frei, B, Morrow, JD, Roberts, LJ, II, Xu, A, Jackson, T, Reyna, R, Klevay, LM, Vita, JA, and Keaney, JF, Jr. Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. Arteriosclerosis Thrombosis, Vasc. Biol., 17, 2975-2981, 1997.

Melanson, M, Nalbantoglu, J, Berkovic, S, Melmed, C, Andermann, E, Roberts, L J, Carpenter, S, Snipes, G J, Andermann, F. Progressive myoclonus epilepsy in young adults with neuropathologic features of Alzheimer's disease. Neurology, 49(6), 1732-3, 1997.

Morrow, J D, Roberts, L J. The isoprostanes: unique bioactive products of lipid peroxidation. Prog Lipid Res, 36(1), 1-21, 1997.

Morrow, JD, and Roberts, LJ, II. The isoprostanes: unique bioactive products of lipid peroxidation. Prog. Lipid Res., 36, 1-21, 1997.

Roberts, L J, Baldwin, T M, Curtis, J M, Handman, E, Foote, S J. Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9. J Exp Med, 185(9), 1705-10, 1997. PMCID:2196292

Roberts, L J, Morrow, J D. The generation and actions of isoprostanes. Biochim Biophys Acta, 1345(2), 121-35, 1997.

Roberts, LJ, II, and Morrow, JD. Generation and actions of isoprostanes. Biochim. Biophys. Acta., 1345, 121-135, 1997.

Shaner, A, Roberts, L J, Eckman, T A, Tucker, D E, Tsuang, J W, Wilkins, J N, Mintz, J. Monetary reinforcement of abstinence from cocaine among mentally ill patients with cocaine dependence. Psychiatr Serv, 48(6), 807-10, 1997.

Smith, C J, Morrow, J D, Roberts, L J, Marnett, L J. Induction of prostaglandin endoperoxide synthase-1 (COX-1) in a human promonocytic cell line by treatment with the differentiating agent TPA. Adv Exp Med Biol, 400A, 99-106, 1997.

Soliman MS, Cunningham ML, Morrow JD, Roberts LJ, II, and Badr MZ. Evidence against peroxisome proliferation-induced hepatic oxidative damage. Biochem. Pharmacol, 53, 1369-1374, 1997.

Soliman, M S, Cunningham, M L, Morrow, J D, Roberts, L J, Badr, M Z. Evidence against peroxisome proliferation-induced hepatic oxidative damage. Biochem Pharmacol, 53(9), 1369-74, 1997.

Taber, D F, Morrow, J D, Roberts, L J. A nomenclature system for the isoprostanes. Prostaglandins, 53(2), 63-7, 1997.

Taber, DF, Morrow, JD, and Roberts, LJ, II. A nomenclature system for the isoprostanes. Prostaglandins, 53, 63-67, 1997.

Waugh RJ, Morrow, JD, Roberts, LJ, II, and Murphy RC. Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. Free Rad. Biol. Med, 23, 943-954, 1997.

Waugh, R J, Morrow, J D, Roberts, L J, Murphy, R C. Identification and relative quantitation of F2-isoprostane regioisomers formed in vivo in the rat. Free Radic Biol Med, 23(6), 943-54, 1997.

Awad, J A, Horn, J L, Roberts, L J, Franks, J J. Demonstration of halothane-induced hepatic lipid peroxidation in rats by quantification of F2-isoprostanes. Anesthesiology, 84(4), 910-6, 1996.

Awad, J A, Roberts, L J, Burk, R F, Morrow, J D. Isoprostanes--prostaglandin-like compounds formed in vivo independently of cyclooxygenase: use as clinical indicators of oxidant damage. Gastroenterol Clin North Am, 25(2), 409-27, 1996.

Awad, JA, Horn, J-L, Roberts, LJ, II, and Franks, JJ. Demonstration of halothane-induced hepatic lipid peroxidation in rats using F2-isoprostanes. Anesthesiology, 84, 910-916, 1996.

Awad, JA, Roberts, LJ, II, Burk, RA, Morrow, JD. Isoprostanes, prostaglandin-like compounds formed in vivo independently of the cyclooxygenase: Use as clinical indicator of oxidant damage. Gastroenterology Clinics N. Am., 25, 409-427, 1996.

Awas, J A, Soteriou, M C, Drougas, J G, Stokes, K A, Roberts, L J, Pinson, C W. Plasma prostaglandin E1 concentrations and hemodynamics during intravenous infusions of prostaglandin E1 in humans and swine. Transplantation, 61(11), 1624-9, 1996.

Bartsch, P, Vock, P, Roberts, LJ, II, and Ballmer, PE. Evidence against a dominant role for increased capillary permeability in the development of acute mountain sickness and high altitude pulmonary edema. J. Appl. Physiol, 81, 1917-1923, 1996.

Choong, K Y, Roberts, L J. Ritual Samoan body tattooing and associated sporotrichosis. Australas J Dermatol, 37(1), 50-3, 1996.

Itoh, S, Lu, R, Bao, Y, Morrow, J D, Roberts, L J, Schuster, V L. Structural determinants of substrates for the prostaglandin transporter PGT. Mol Pharmacol, 50(4), 738-42, 1996.

Itoh, S, Morrow, JD, Roberts, LJ, II, and Schuster, VL. Structural determinants of substrates for the prostaglandin transporter "PGT". Mol. Pharmacol., 50, 736-742, 1996.

Kleger, G R, B??rtsch, P, Vock, P, Heilig, B, Roberts, L J, Ballmer, P E. Evidence against an increase in capillary permeability in subjects exposed to high altitude. J Appl Physiol, 81(5), 1917-23, 1996.

Morrow, J D, Awad, J A, Wu, A, Zackert, W E, Daniel, V C, Roberts, L J. Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo. J Biol Chem, 271(38), 23185-90, 1996.

Morrow, J D, Roberts, L J. The isoprostanes. Current knowledge and directions for future research. Biochem Pharmacol, 51(1), 1-9, 1996.

Morrow, JD, Awad, JA, Wu, A., Zackert, WE, Daniel, VC, and Roberts, LJ, II. Free radical-induced generation of thromboxane-like compounds (isothromboxanes) in vivo. J. Biol. Chem, 271, 23185-23190, 1996.

Morrow, JD, and Roberts, LJ, II. The isoprostanes: current knowledge and directions for future research. Biochem. Pharmacol, 51, 1-9,, 1996.

Morrow, JD, and Roberts, LJ, II. Measurement of F2-isoprostanes: prostaglandin-like products of lipid peroxidation. Free Radicals: A Practical Approach. NA Punchard and FJ Kelly, Eds., Oxford University Press, New York, , pp. 147-157, 1996.

Roberts, L J. Knowledge and use of periconceptual folic acid supplements by British Forces Germany personnel and dependents. J R Army Med Corps, 142(3), 116-9, 1996.

Roberts, L J, II, Moore, KP, Zackert, WE, Oates, JA, and Morrow, JD. Identification of the major urinary metabolite of the F2-isoprostane, 8-iso-prostaglandin F2 , in humans. J. Biol. Chem., 271, 20617-20620, 1996.

Roberts, L J, Moore, K P, Zackert, W E, Oates, J A, Morrow, J D. Identification of the major urinary metabolite of the F2-isoprostane 8-iso-prostaglandin F2alpha in humans. J Biol Chem, 271(34), 20617-20, 1996.

Stein, C M, Tanner, S B, Awad, J A, Roberts, L J, Morrow, J D. Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. Arthritis Rheum, 39(7), 1146-50, 1996.

Stein, CM, Awad, JA, Tanner, SB, Roberts, LJ, II, and Morrow, JD. Evidence for free radical mediated injury (isoprostane overproduction) in scleroderma. Arthtitis and Rheumatism, 39, 1146-1150, 1996.

Yang, Z P, Morrow, J, Wu, A, Roberts, L J, Dettbarn, W D. Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo. Biochem Pharmacol, 52(2), 357-61, 1996.

Yang, ZP, Wu, A, Morrow, JD, Roberts, LJ, II, and Dettbarn, W-D. Increases in malondialdehyde-thiobarbituric acid complex (MDA-TBA) and F2-isoprostanes in diisopropyl fluorophosphate induced muscle hyperactivity. Biochem. Pharmacol., 52, 357-361, 1996.

Awad, J, Morrow, J, Roberts, L J. Comments on prostaglandin F2 alpha rises in response to hydroxyl radical generated in vivo. Free Radic Biol Med, 19(6), 944-6, 1995.

Bewley, S, Roberts, L J, Mackinson, A M, Rodeck, C H. First trimester fetal nuchal translucency: problems with screening the general population. 2. Br J Obstet Gynaecol, 102(5), 386-8, 1995.

Downard, C D, Roberts, L J, Morrow, J D. Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo. Clin Pharmacol Ther, 57(4), 441-5, 1995.

Moore, K P, Darley-Usmar, V, Morrow, J, Roberts, L J. Formation of F2-isoprostanes during the oxidation of human low density lipoprotein by peroxynitrite. Adv Prostaglandin Thromboxane Leukot Res, 23, 225-7, 1995.

Moore, K P, Darley-Usmar, V, Morrow, J, Roberts, L J. Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. Circ Res, 77(2), 335-41, 1995.

Moore, KP, Darley-Usmar, V, Morrow JD, and Roberts, LJ, II. Formation of F2-isoprostanes during the oxidation of human low density lipoprotein and plasma by peroxynitrite. Circ. Res, 77, 335-341, 1995.

Morrow, J D, Frei, B, Longmire, A W, Gaziano, J M, Lynch, S M, Shyr, Y, Strauss, W E, Oates, J A, Roberts, L J. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. N Engl J Med, 332(18), 1198-203, 1995.

Morrow, J D, Guzzo, C, Lazarus, G, Oates, J A, Roberts, L J. Improved diagnosis of mastocytosis by measurement of the major urinary metabolite of prostaglandin D2. J Invest Dermatol, 104(6), 937-40, 1995.

Morrow, JD, Frei, B, Longmire, AW, Gaziano, JM, Lynch, SM, Strauss, WE, Oates, JA, Roberts, LJ, II. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers: Smoking as a cause of oxidative damage. N. Eng. J. Med., 332, 1198-1203, 1995.

Murray, J., Mullins, M., Knapp, H., Keller, S., Serafin, W., Roberts, L., Struthers, B., Oates, J. Regulation of the Immune Response by Eicosanoids: Pharmacology and Clinical Effects of Prostaglandin E in Aspirin-Sensitive Syndromes. Am J Ther, 2(10), 739-748, 1995.

Rangachari, P K, Betti, P A, Prior, E T, Roberts, L J. Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?. J Pharmacol Exp Ther, 275(2), 611-7, 1995.

Roberts, L J, Bewley, S, Mackinson, A M, Rodeck, C H. First trimester fetal nuchal translucency: problems with screening the general population. 1. Br J Obstet Gynaecol, 102(5), 381-5, 1995.

Roberts, L J, Morrow, J D. The isoprostanes: novel markers of lipid peroxidation and potential mediators of oxidant injury. Adv Prostaglandin Thromboxane Leukot Res, 23, 219-24, 1995.

Salahucleen, A, Bach, K, Morrow, JD, and Roberts, LJ, II. Hydrogen peroxide induces 21-aminosteroid-inhibitable F2-isoprostane production and cytolysis in renal tubular epithelial cells. J. Am. Soc. Nephrol., 6, 1300-1303, 1995.

Shaner, A, Eckman, TA, Roberts, LJ, Wilkins, JN, Tucker, DE, Tsuang, JW, Mintz, J. Disability income, cocaine use, and repeated hospitalization among schizophrenic cocaine abusers--a government-sponsored revolving door. N Engl J Med, 333(12), 777-83, 1995.

Simon, TC, Roberts, LJ, Gordon, JI. A 20-nucleotide element in the intestinal fatty acid binding protein gene modulates its cell lineage-specific, differentiation-dependent, and cephalocaudal patterns of expression in transgenic mice. Proc Natl Acad Sci U S A, 92(19), 8685-9, 1995. PMCID:41031

Awad, J A, Burk, R F, Roberts, L J. Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats. J Pharmacol Exp Ther, 270(3), 858-64, 1994.

Awad, J A, Morrow, J D, Hill, K E, Roberts, L J, Burk, R F. Detection and localization of lipid peroxidation in selenium- and vitamin E-deficient rats using F2-isoprostanes. J Nutr, 124(6), 810-6, 1994.

Awad, J A, Morrow, J D, Roberts, L J. Detection of the major urinary metabolite of prostaglandin D2 in the circulation: demonstration of elevated levels in patients with disorders of systemic mast cell activation. J Allergy Clin Immunol, 93(5), 817-24, 1994.

Awad, JA, Burk, RF, and Roberts, LJ, II. Effect of selenium deficiency and glutathione modulating agents on diquat toxicity and lipid peroxidation. J. Pharmac. Exp. Therap., 270, 858-864, 1994.

Awad, JA, Morrow, JD, Hill, KE, Roberts, LJ, II, and Burk, RF. Detection and localization of lipid peroxidation in vitamin E and selenium deficient rats using F2-isoprostanes. J. Nutr., 124, 810-816, 1994.

Crosland, J G, Roberts, L J. Pulsed dye laser therapy for port-wine stains in children. J Pediatr, 124(1), 161-2, 1994.

DuBois, R N, Awad, J, Morrow, J, Roberts, L J, Bishop, P R. Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. J Clin Invest, 93(2), 493-8, 1994. PMCID:293869

Longmire, A W, Roberts, L J, Morrow, J D. Actions of the E2-isoprostane, 8-ISO-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: additional evidence for the existence of a unique isoprostane receptor. Prostaglandins, 48(4), 247-56, 1994.

Longmire, A W, Swift, L L, Roberts, L J, Awad, J A, Burk, R F, Morrow, J D. Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. Biochem Pharmacol, 47(7), 1173-7, 1994.

Longmire, AW, Roberts, LJ, II, and Morrow, J.D. Actions of the E2-isoprostane, 8-iso-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: Additional evidence for the existence of a unique isoprostane receptor. Prostaglandins, 48, 247-256, 1994.

Longmire, AW, Swift, LL, Roberts, LJ, II, Awad, JA, Burk, RF, and Morrow, J.D. Effect of oxygen tension on the generation of F2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. Biochem. Pharmacol., 47, 1173-1177, 1994.

Lynch, S M, Morrow, J D, Roberts, L J, Frei, B. Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. J Clin Invest, 93(3), 998-1004, 1994. PMCID:294019

Lynch, SM, Morrow, JD, Roberts, LJ, II, and Frei, B. Formation of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in human plasma and isolated low density lipoproteins exposed to metal ion-dependent and -independent oxidative stress. J. Clin. Invest., 93, 998-1004, 1994.

Morrow, J D, Minton, T A, Awad, J A, Roberts, L J. Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans following the application of sorbic acid. Arch Dermatol, 130(11), 1408-12, 1994.

Morrow, J D, Minton, T A, Badr, K F, Roberts, L J. Evidence that the F2-isoprostane, 8-epi-prostaglandin F2 alpha, is formed in vivo. Biochim Biophys Acta, 1210(2), 244-8, 1994.

Morrow, J D, Minton, T A, Mukundan, C R, Campbell, M D, Zackert, W E, Daniel, V C, Badr, K F, Blair, I A, Roberts, L J. Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. J Biol Chem, 269(6), 4317-26, 1994.

Morrow, J D, Roberts, L J. Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism. Methods Enzymol, 233, 163-74, 1994.

Morrow, JD, Badr, KF, and Roberts, LJ, II. Evidence that the F2-isoprostane, 8-epi-PGF2 , is formed in vivo. Biochim. Biophys. Acta., 1210, 244-248, 1994.

Morrow, JD, Minton, TA, Mukundan, CR, Campbell, MD, Zackert, WE, Daniel, VC. Badr, KF, Blair, IA, and Roberts, LJ, II. Free radical induced generation of isoprostanes in vivo: Evidence for the formation of D-ring and E-ring isoprostanes. J. Biol. Chem., 269, 4317-4326, 1994.

Morrow, JD, and Roberts, LJ, II. Mass spectrometric method for quantification of prostanoids (F2-isoprostanes) produced by a non-cyclooxygenase free radical catalyzed mechanism. Methods Enzymol., 233, 163-174, 1994.

Nassar, G M, Morrow, J D, Roberts, L J, Lakkis, F G, Badr, K F. Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. J Biol Chem, 269(44), 27631-4, 1994.

Roberts, L J, Beardsworth, S A, Trew, G. Labour following caesarean section: current practice in the United Kingdom. Br J Obstet Gynaecol, 101(2), 153-5, 1994.

Roberts, L J, Morrow, J D. Isoprostanes. Novel markers of endogenous lipid peroxidation and potential mediators of oxidant injury. Ann N Y Acad Sci, 744, 237-42, 1994.

Roberts, LJ, II, and Morrow, JD. Isoprostanes: Novel markers of endogenous lipid peroxidation and potential mediators of oxidant injury. Annals N.Y. Acad. Sci, 744, 237-242, 1994.

Rodeck, C H, Roberts, L J. Successful treatment of fetal cardiac arrest by left ventricular exchange transfusion. Fetal Diagn Ther, 9(4), 213-7, 1994.

Stein, C M, Longmire, A W, Minton, T A, Roberts, L J, Pincus, T, Morrow, J D. Cyclosporine-induced alterations in renal function are not associated with lipid peroxidation. Transplantation, 58(3), 386-8, 1994.

Stein, DM, Longmire, AW, Minton, TA, Roberts, LJ, II, Pincus, MD, and Morrow, JD. Cyclosporine-induced alterations in renal function are not associated with lipid peroxidation. Transplantation, 58, 386-388, 1994.

Awad, J A, Morrow, J D, Roberts, L J. Simplification of the mass spectrometric assay for the major urinary metabolite of prostaglandin D2. J Chromatogr, 617(1), 124-8, 1993.

Awad, J A, Morrow, J D, Takahashi, K, Roberts, L J. Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma. J Biol Chem, 268(6), 4161-9, 1993.

Awad, JA, Morrow, JD, and Roberts, LJ, II. Identification of metabolites of noncyclooxygenase derived prostaglandin F2-like compounds (F2-isoprostanes) in human urine and plasma. J. Biol. Chem., 268, 4161-4169, 1993.

Cox, S E, Roberts, L J, Bergstresser, P R. Prevention of skin cancer in xeroderma pigmentosum: the physician as advocate. J Am Acad Dermatol, 29(6), 1045-6, 1993.

Fukunaga, M, Makita, N, Roberts, L J, Morrow, J D, Takahashi, K, Badr, K F. Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells. Am J Physiol, 264(6 Pt 1), C1619-24, 1993.

Fukunaga, M, Makita, N, Roberts, LJ, II, Morrow, JD, Takahashi, K, and Badr, KF. Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells. Am. J. Physiol., 263(Cell Physiol.33), C1619-C1624, 1993.

Kang, HK, Morrow, JD, Roberts, LJ, II, Newman, JH, and Banerjee, M. Airway and vascular effects of 8-epi-prostaglandin F2 in isolated perfused rat lung. J. Appl. Physiol., 74, 460-465, 1993.

Kang, K H, Morrow, J D, Roberts, L J, Newman, J H, Banerjee, M. Airway and vascular effects of 8-epi-prostaglandin F2 alpha in isolated perfused rat lung. J Appl Physiol, 74(1), 460-5, 1993.

Kayganich, KA, Rose, DM, Murphy, RC, Morrow, JD, and Roberts, LJ, II. Collision induced dissociation of isoprostane-containing phospholipids. J. Lipid Res., 34, 1229-1235, 1993.

Kayganich-Harrison, K A, Rose, D M, Murphy, R C, Morrow, J D, Roberts, L J. Collision-induced dissociation of F2-isoprostane-containing phospholipids. J Lipid Res, 34(7), 1229-35, 1993.

Morrow, J D, Moore, K P, Awad, J A, Ravenscraft, M D, Marini, G, Badr, K F, Williams, R, Roberts, L J. Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. J Lipid Mediat, 6(1-3), 417-20, 1993.

Morrow, JD, Moore, KP, Awad, JA, Ravenscraft, MD, Marini, G, Badr, KF, Williams, R, and Roberts, LJ, II. Marked overproduction of non-cycloxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. J. Lip. Mediators, 6, 417-420, 1993.

Roberts, L J. Induction of labour. BMJ, 307(6895), 66-7, 1993. PMCID:1678463

Smith, C J, Morrow, J D, Roberts, L J, Marnett, L J. Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). Biochem Biophys Res Commun, 192(2), 787-93, 1993.

Spatz, M, Stanimirovic, D, Uematsu, S, Roberts, L J, Bembry, J, McCarron, R M. Prostaglandin D2 and endothelin-1 induce the production of prostaglandin F2 alpha, 9 alpha, 11 beta-prostaglandin F2, prostaglandin E2, and thromboxane in capillary endothelium of human brain. Prostaglandins Leukot Essent Fatty Acids, 49(4), 789-93, 1993.

Banerjee, M, Kang, K H, Morrow, J D, Roberts, L J, Newman, J H. Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ. Am J Physiol, 263(3 Pt 2), H660-3, 1992.

Banerjee, M, Kang, KH, Morrow, JD, Roberts, LJ, II, and Newman, JH. Effects of a novel non-cyclooxygenase derived prostaglandin, 8-epi-PGF2 , in rabbit lung in situ. Am. J. Physiol. 263, (Heart Circ. Physiol 32), H660-H663, 1992.

Fink, R L, Roberts, L J, Scott, M. The role of manometry, electromyography and radiology in the assessment of intractable constipation. Aust N Z J Surg, 62(12), 959-64, 1992.

Fink, R L, Roberts, L J, Scott, M. The role of manometry, electromyography and radiology in the assessment of faecal incontinence. Aust N Z J Surg, 62(12), 951-8, 1992.

Morrow, J D, Awad, J A, Boss, H J, Blair, I A, Roberts, L J. Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci U S A, 89(22), 10721-5, 1992. PMCID:50413

Morrow, J D, Awad, J A, Kato, T, Takahashi, K, Badr, K F, Roberts, L J, Burk, R F. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. J Clin Invest, 90(6), 2502-7, 1992. PMCID:443408

Morrow, J D, Awad, J A, Oates, J A, Roberts, L J. Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans. J Invest Dermatol, 98(5), 812-5, 1992.

Morrow, J D, Minton, T A, Roberts, L J. The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist. Prostaglandins, 44(2), 155-63, 1992.

Morrow, JD, Awad, JA, Boss, HJ, Blair, IA, and Roberts, LJ, II. Non- cyclooxygenase derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc. Natl. Acad. Sci., 89, 10721-10725, 1992.

Morrow, JD, Awad, JA, Kato, T, Takahashi, K, Badr, KF, Roberts, LJ, II, and Burk, R.F. Formation of novel non-cyclooxygenase derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity, an animal model of lipid peroxidation. J. Clin. Invest., 90, 2502-2507, 1992.

Morrow, JD, Minton, TA, and Roberts, LJ, II. The F2-isoprostane, 8-epi-prostaglandin F2 , a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist. Prostaglandins, 44, 155-163, 1992.

Roberts, L J, Knight, V A. A physiologic concept of exercise-induced pulmonary hemorrhage in horses. J Am Vet Med Assoc, 201(5), 666-7, 1992.

Roberts, L J, Shaner, A, Eckman, T A, Tucker, D E, Vaccaro, J V. Effectively treating stimulant-abusing schizophrenics: mission impossible?. New Dir Ment Health Serv, (53), 55-65, 1992.

Takahashi, K, Nammour, T M, Fukunaga, M, Ebert, J, Morrow, J D, Roberts, L J, Hoover, R L, Badr, K F. Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. J Clin Invest, 90(1), 136-41, 1992. PMCID:443072

Takahashi, K, Nammour, TM, Ebert, J, Morrow, JD, Roberts, LJ, II and Badr, KF. Glomerular actions of a free radical generated novel prostaglandin, 8-epi-prostaglandin F2 in the rat: Evidence for interaction with thromboxane A2 receptors. J. Clin. Invest., 90, 136-141, 1992.

Arzubiaga, C, Morrow, J, Roberts, L J, Biaggioni, I. Neuropeptide Y, a putative cotransmitter in noradrenergic neurons, induces mast cell degranulation but not prostaglandin D2 release. J Allergy Clin Immunol, 87(1 Pt 1), 88-93, 1991.

Atsmon, J, Freeman, M L, Meredith, M J, Sweetman, B J, Roberts, L J. Modulation of the antiproliferative activity of 9-deoxy-delta 9,delta 12(E)-PGD2 by conjugation with intracellular glutathione. Adv Prostaglandin Thromboxane Leukot Res, 21B, 887-90, 1991.

Duncan, B W, Harrison, M R, Zanjani, E D, Tarantal, A F, Adzick, N S, Bradley, S M, Longaker, M T, Jennings, R W, Roberts, L J, Bigler, M E. Immunologic evaluation of hematopoietic chimeric rhesus monkeys. Transplant Proc, 23(1 Pt 1), 841-3, 1991.

Guzzo, C, Lavker, R, Roberts, L J, Fox, K, Schechter, N, Lazarus, G. Urticaria pigmentosa. Systemic evaluation and successful treatment with topical steroids. Arch Dermatol, 127(2), 191-6, 1991.

Morrow, J D, Hill, K E, Burk, R F, Nammour, T M, Badr, K F, Roberts, L J. Formation of unique biologically active prostaglandins in vivo by a non-cyclooxygenase free radical catalyzed mechanism. Adv Prostaglandin Thromboxane Leukot Res, 21A, 125-8, 1991.

Morrow, J D, Margolies, G R, Rowland, J, Roberts, L J. Evidence that histamine is the causative toxin of scombroid-fish poisoning. N Engl J Med, 324(11), 716-20, 1991.

Morrow, J D, Prakash, C, Awad, J A, Duckworth, T A, Zackert, W E, Blair, I A, Oates, J A, Roberts, L J. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay. Anal Biochem, 193(1), 142-8, 1991.

Morrow, J D, Prakash, C, Duckworth, T A, Zackert, W E, Blair, I A, Oates, J A, Roberts, L J. A stable isotope dilution mass spectrometric assay for the major urinary metabolite of PGD2. Adv Prostaglandin Thromboxane Leukot Res, 21A, 315-8, 1991.

Morrow, J D, Roberts, L J. Quantification of noncyclooxygenase derived prostanoids as a marker of oxidative stress. Free Radic Biol Med, 10(3-4), 195-200, 1991.

Morrow, JD, Rowland, J, Margolies, G, and Roberts, LJ, II. Evidence that histamine is the causative toxin of scombroid fish poisoning. N. Engl. J. Med., 324, 716-720, 1991.

Morrow, JD, and Roberts, LJ, II. . Quantification of non-cyclooxygenase derived prostaglandins as a potential non-invasive marker of oxidative stress. Free Rad. Biol. Med., 10, 195-200, 1991.

Roberts, L J. Elective section after two sections--where's the evidence?. Br J Obstet Gynaecol, 98(12), 1199-202, 1991.

Roberts, L J. Idiopathic thrombocytopenic purpura in pregnancy: a randomized trial on the effect of antenatal low dose corticosteroids on neonatal platelet count. Br J Obstet Gynaecol, 98(3), 334-6, 1991.

Roberts, L J, Luke, D A, Rappaport, J, Seidman, E, Toro, P A, Reischl, T M. Charting uncharted terrain: a behavioral observation system for mutual help groups. Am J Community Psychol, 19(5), 715-37, 1991.

Roberts, L J, Oates, J A. Biochemical diagnosis of systemic mast cell disorders. J Invest Dermatol, 96(3), 19S-24S; discussion 24S-25S, 1991.

Roberts, L J, Young, K R. The management of prolonged pregnancy--an analysis of women's attitudes before and after term. Br J Obstet Gynaecol, 98(11), 1102-6, 1991.

Roberts, LJ, Oates, JA. Biochemical diagnosis of systemic mast cell disorders. J Invest Dermatol, 96(3 Suppl), 19S-24S; discussion 24S-25S; 60S-65S, 1991.

Sladek, K, Sheller, J R, FitzGerald, G A, Morrow, J D, Roberts, L J. Formation of PGD2 after allergen inhalation in atopic asthmatics. Adv Prostaglandin Thromboxane Leukot Res, 21A, 433-6, 1991.

Atsmon, J, Freeman, M L, Meredith, M J, Sweetman, B J, Roberts, L J. Conjugation of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 with intracellular glutathione and enhancement of its antiproliferative activity by glutathione depletion. Cancer Res, 50(6), 1879-85, 1990.

Atsmon, J, Sweetman, B J, Baertschi, S W, Harris, T M, Roberts, L J. Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2. Biochemistry, 29(15), 3760-5, 1990.

Boh, E, Roberts, L J, Lieu, T S, Gammon, W R, Sontheimer, R D. Epidermolysis bullosa acquisita preceding the development of systemic lupus erythematosus. J Am Acad Dermatol, 22(4), 587-93, 1990.

Hendin, B N, Longaker, M T, Finkbeiner, W E, Roberts, L J, Stern, R. Hyaluronic acid deposition in cardiac myxomas: localization using a hyaluronate-specific binding protein. Am J Cardiovasc Pathol, 3(3), 209-15, 1990.

Morrow, J D, Harris, T M, Roberts, L J. Noncyclooxygenase oxidative formation of a series of novel prostaglandins: analytical ramifications for measurement of eicosanoids. Anal Biochem, 184(1), 1-10, 1990.

Morrow, J D, Hill, K E, Burk, R F, Nammour, T M, Badr, K F, Roberts, L J. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci U S A, 87(23), 9383-7, 1990. PMCID:55169

Morrow, JD, Hill, KE, Burk, RF, Nammour, TM, Badr, KF, and Roberts, LJ, II. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase free radical catalyzed mechanism. Proc. Natl. Acad. Sci., USA, 87, 9383-9387, 1990.

Roberts, L J. Premature ovarian failure and endometrial ablation. Br J Hosp Med, 44(5), 318, 1990.

Sebaldt, R J, Sheller, J R, Oates, J A, Roberts, L J, FitzGerald, G A. Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci U S A, 87(18), 6974-8, 1990. PMCID:54664

Smith, S, Anthony, L, Roberts, L J, Oates, J A, Pincus, T. Resolution of musculoskeletal symptoms in the carcinoid syndrome after treatment with the somatostatin analog octreotide. Ann Intern Med, 112(1), 66-8, 1990.

Smith, W L, Borgeat, P, Hamberg, M, Roberts, L J, Willis, A l, Yamamoto, S, Ramwell, P W, Rokach, J, Samuelsson, B, Corey, E J. Nomenclature. Methods Enzymol, 187, 1-9, 1990.

Wendelborn, D F, Morrow, J D, Roberts, L J. Quantification of 9 alpha, 11 beta-prostaglandin F2 by stable isotope dilution mass spectrometric assay. Methods Enzymol, 187, 51-62, 1990.

Dworski, R, Sheller, J R, Wickersham, N E, Oates, J A, Brigham, K L, Roberts, L J, Fitzgerald, G A. Allergen-stimulated release of mediators into sheep bronchoalveolar lavage fluid. Effect of cyclooxygenase inhibition. Am Rev Respir Dis, 139(1), 46-51, 1989.

Fleck, R M, Barnadas, M, Schulz, W W, Roberts, L J, Freeman, R G. Harlequin ichthyosis: an ultrastructural study. J Am Acad Dermatol, 21(5 Pt 1), 999-1006, 1989.

Morrow, J D, Parsons, W G, Roberts, L J. Release of markedly increased quantities of prostaglandin D2 in vivo in humans following the administration of nicotinic acid. Prostaglandins, 38(2), 263-74, 1989.

Parsons, W G, Roberts, L J. Transformation of prostaglandin D2 to isomeric prostaglandin F2 compounds by human eosinophils: a potential mast cell-eosinophil interaction. Adv Prostaglandin Thromboxane Leukot Res, 19, 499-502, 1989.

Roberts, L J. Long-term survival of a harlequin fetus. J Am Acad Dermatol, 21(2 Pt 2), 335-9, 1989.

Arthur, H, Austin, L, Roberts, L J. A pilot trial of plasma infusions in Duchenne muscular dystrophy. Aust Paediatr J, 24 Suppl 1, 24-30, 1988.

Dworski, R, Wendelborn, D F, Sheller, J R, FitzGerald, G A, Roberts, L J. Prostaglandins in Ascaris antigen. J Allergy Clin Immunol, 82(3 Pt 1), 484, 1988.

Oates, J A, FitzGerald, G A, Branch, R A, Jackson, E K, Knapp, H R, Roberts, L J. Clinical implications of prostaglandin and thromboxane A2 formation (1). N Engl J Med, 319(11), 689-98, 1988.

Oates, J A, FitzGerald, G A, Branch, R A, Jackson, E K, Knapp, H R, Roberts, L J. Clinical implications of prostaglandin and thromboxane A2 formation (2). N Engl J Med, 319(12), 761-7, 1988.

Parsons, W G, Roberts, L J. Transformation of prostaglandin D2 to isomeric prostaglandin F2 compounds by human eosinophils. A potential mast cell-eosinophil interaction. J Immunol, 141(7), 2413-9, 1988.

Rendon, M I, Roberts, L J, Tharp, M D. Linear cutaneous lesions of Kaposi's sarcoma: a clinical clue to the diagnosis of acquired immunodeficiency syndrome. Arch Dermatol, 124(3), 327-9, 1988.

Roberts, L J. Carcinoid syndrome and disorders of systemic mast-cell activation including systemic mastocytosis. Endocrinol Metab Clin North Am, 17(2), 415-36, 1988.

Roberts, L J, Fink, C W. Childhood polymyositis/dermatomyositis. Clin Dermatol, 6(2), 36-46, 49-51, 1988.

Soberman, R J, Sutyak, J P, Okita, R T, Wendelborn, D F, Roberts, L J, Austen, K F. The identification and formation of 20-aldehyde leukotriene B4. J Biol Chem, 263(17), 7996-8002, 1988.

Toro, P A, Reischl, T M, Zimmerman, M A, Rappaport, J, Seidman, E, Luke, D A, Roberts, L J. Professionals in mutual help groups: impact on social climate and members' behavior. J Consult Clin Psychol, 56(4), 631-2, 1988.

Wendelborn, D F, Seibert, K, Roberts, L J. Isomeric prostaglandin F2 compounds arising from prostaglandin D2: a family of icosanoids produced in vivo in humans. Proc Natl Acad Sci U S A, 85(2), 304-8, 1988. PMCID:279536

Lynes, W L, Flynn, S D, Shortliffe, L D, Lemmers, M, Zipser, R, Roberts, L J, Stamey, T A. Mast cell involvement in interstitial cystitis. J Urol, 138(4), 746-52, 1987.

Prakash, C, Roberts, L J, Saleh, S, Taber, D F, Blair, I A. Synthesis of putative prostaglandin D2 metabolites. Adv Prostaglandin Thromboxane Leukot Res, 17B, 781-7, 1987.

Roberts, L J. Recent metabolic findings bring into question the reliability of existing methods for quantification of PGF2 alpha and its metabolites in human biological fluids. Adv Prostaglandin Thromboxane Leukot Res, 17B, 608-10, 1987.

Roberts, L J, Seibert, K, Liston, T E, Tantengco, M V, Robertson, R M. PGD2 is transformed by human coronary arteries to 9 alpha, 11 beta-PGF2, which contracts human coronary artery rings. Adv Prostaglandin Thromboxane Leukot Res, 17A, 427-9, 1987.

Roberts, L J, Shadwick, C F, Bergstresser, P R. Zinc deficiency in two full-term breast-fed infants. J Am Acad Dermatol, 16(2 Pt 1), 301-4, 1987.

Roberts, L J, Sontheimer, R D. Chronic bullous dermatosis of childhood: immunopathologic studies. Pediatr Dermatol, 4(1), 6-10, 1987.

Seibert, K, Sheller, J R, Roberts, L J. 9 alpha, 11 beta-prostaglandin F2: formation and metabolism by human lung and contractile effects on human bronchial smooth muscle. Adv Prostaglandin Thromboxane Leukot Res, 17A, 189-91, 1987.

Seibert, K, Sheller, J R, Roberts, L J. (5Z,13E)-(15S)-9 alpha,11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2): formation and metabolism by human lung and contractile effects on human bronchial smooth muscle. Proc Natl Acad Sci U S A, 84(1), 256-60, 1987. PMCID:304182

Stier, C T, Roberts, L J, Wong, P Y. Renal response to 9 alpha, 11 beta-prostaglandin F2 in the rat. J Pharmacol Exp Ther, 243(2), 487-91, 1987.

Watanabe, K, Iguchi, Y, Iguchi, S, Arai, Y, Hayaishi, O, Roberts, L J. Stereospecific conversion of prostaglandin D2 to 9 alpha, 11 beta-prostaglandin F2 and prostaglandin H2 to prostaglandin F2 alpha by PGF synthetase. Adv Prostaglandin Thromboxane Leukot Res, 17A, 44-6, 1987.

Wendelborn, D F, Seibert, K, Roberts, L J. Isomeric prostaglandin F2 compounds: a new family of eicosanoids produced in vivo in humans. Adv Prostaglandin Thromboxane Leukot Res, 17A, 47-9, 1987.

Massicot, J G, Soberman, R J, Ackerman, N R, Heavey, D, Roberts, L J, Austen, K F. Workshop: Potential therapeutic uses of inhibitors of leukotriene generation and function. June 23, 1986, Bethesda, Maryland. Sponsored by the National Institute of Allergy and Infectious Diseases and the World Health Organization Collaborating Center for Allergic Diseases. Prostaglandins, 32(4), 481-94, 1986.

Murray, J J, Tonnel, A B, Brash, A R, Roberts, L J, Gosset, P, Workman, R, Capron, A, Oates, J A. Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med, 315(13), 800-4, 1986.

Vire, G, Roberts, L J, King, L E. Urticaria pigmentosa and natural sunlight. J Am Acad Dermatol, 14(4), 687-8, 1986.

Watanabe, K, Iguchi, Y, Iguchi, S, Arai, Y, Hayaishi, O, Roberts, L J. Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9 alpha-11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2 alpha by bovine lung prostaglandin F synthase. Proc Natl Acad Sci U S A, 83(6), 1583-7, 1986. PMCID:323127

Forman, M B, Oates, J A, Robertson, D, Robertson, R M, Roberts, L J, Virmani, R. Increased adventitial mast cells in a patient with coronary spasm. N Engl J Med, 313(18), 1138-41, 1985.

Liston, T E, Oates, J A, Roberts, L J. Prostaglandin D2 is metabolized in humans to 9 alpha,11 beta-prostaglandin F2, a novel biologically active prostaglandin. Adv Prostaglandin Thromboxane Leukot Res, 15, 365-7, 1985.

Liston, T E, Roberts, L J. Transformation of prostaglandin D2 to 9 alpha, 11 beta-(15S)-trihydroxyprosta-(5Z,13E)-dien-1-oic acid (9 alpha, 11 beta-prostaglandin F2): a unique biologically active prostaglandin produced enzymatically in vivo in humans. Proc Natl Acad Sci U S A, 82(18), 6030-4, 1985. PMCID:390693

Liston, T E, Roberts, L J. Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer. J Biol Chem, 260(24), 13172-80, 1985.

Murray, J J, Tonnel, A B, Brash, A R, Roberts, L J, Gosset, P, Workman, R, Capron, A, Oates, J A. Prostaglandin D2 is released during acute allergic bronchospasm in man. Trans Assoc Am Physicians, 98, 275-80, 1985.

Rappaport, J, Seidman, E, Toro, P A, McFadden, L S, Reischl, T M, Roberts, L J, Salem, D A, Stein, C H, Zimmerman, M A. Collaborative research with a mutual help organization. Soc Policy, 15(3), 12-24, 1985.

Roberts, L J, Aulsebrook, K A, Oates, J A. Comparative evaluation of the radioenzymatic method for the determination of urinary histamine with a mass spectrometric assay. J Chromatogr, 338(1), 41-9, 1985.

Roberts, L J, Sweetman, B J. Metabolic fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosis. Prostaglandins, 30(3), 383-400, 1985.

Roberts, L J. Recurrent syncope due to systemic mastocytosis. Hypertension, 6(2 Pt 1), 285-94, 1984.

Roberts, L J. Pentafluorobenzyl derivative of histamine for determination by gas chromatography-negative ion chemical ionization mass spectrometry. J Chromatogr, 287(1), 155-60, 1984.

Roberts, L J, Oates, J A. Accurate and efficient method for quantification of urinary histamine by gas chromatography negative ion chemical ionization mass spectrometry. Anal Biochem, 136(1), 258-63, 1984.

FitzGerald, G A, Maas, R L, Lawson, J A, Oates, J A, Roberts, L J, Brash, A R. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. Adv Prostaglandin Thromboxane Leukot Res, 11, 265-6, 1983.

FitzGerald, G A, Oates, J A, Hawiger, J, Maas, R L, Roberts, L J, Lawson, J A, Brash, A R. Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man. J Clin Invest, 71(3), 676-88, 1983. PMCID:436917

Kootte, A M, Haak, A, Roberts, L J. The flush syndrome: an expression of systemic mastocytosis with increased prostaglandin D2 production. Neth J Med, 26(1), 18-20, 1983.

Roberts, L J, Bloomgarden, Z T, Marney, S R, Rabin, D, Oates, J A. Histamine release from a gastric carcinoid: provocation by pentagastrin and inhibition by somatostatin. Gastroenterology, 84(2), 272-5, 1983.

Roberts, L J, Ross, E. Chronic airflow limitation. Nurse Pract, 8(10), 21, 24-5, 1983.

Scott, H W, Parris, W C, Sandidge, P C, Oates, J A, Roberts, L J. Hazards in operative management of patients with systemic mastocytosis. Ann Surg, 197(5), 507-14, 1983. PMCID:1353019

Turk, J, Maas, R L, Roberts, L J, Brash, A R, Oates, J A. Conjugated triene metabolites of arachidonic acid derived from dioxygenation at carbon-15: origin from eosinophil and mechanisms of biosynthesis. Adv Prostaglandin Thromboxane Leukot Res, 11, 123-32, 1983.

Turk, J, Oates, J A, Roberts, L J. Intervention with epinephrine in hypotension associated with mastocytosis. J Allergy Clin Immunol, 71(2), 189-92, 1983.

Turk, J, Rand, T H, Maas, R L, Lawson, J A, Brash, A R, Roberts, L J, Colley, D G, Oates, J A. Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils. Biochim Biophys Acta, 750(1), 78-90, 1983.

Lewis, R A, Soter, N A, Diamond, P T, Austen, K F, Oates, J A, Roberts, L J. Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. J Immunol, 129(4), 1627-31, 1982.

Maas, R L, Taber, D F, Roberts, L J. Quantitative assay of urinary 2,3-dinor thromboxane B2 by GC-MS. Methods Enzymol, 86, 592-603, 1982.

Roberts, L J. Quantification of the PGD2 urinary metabolite 9 alpha-hydroxy-11, 15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid by stable isotope dilution mass spectrometric assay. Methods Enzymol, 86, 559-70, 1982.

Roberts, L J, Brash, A R, Oates, J A. Metabolic fate of thromboxane A2 and prostacyclin. Adv Prostaglandin Thromboxane Leukot Res, 10, 211-25, 1982.

Roberts, L J, Fields, J P, Oates, J A. Mastocytosis without urticaria pigmentosa: a frequently unrecognized cause of recurrent syncope. Trans Assoc Am Physicians, 95, 36-41, 1982.

Roberts, L J, Turk, J W, Oates, J A. Shock syndrome associated with mastocytosis: pharmacologic reversal of the acute episode and therapeutic prevention of recurrent attacks. Adv Shock Res, 8, 145-52, 1982.

Turk, J, Maas, R L, Brash, A R, Roberts, L J, Oates, J A. Arachidonic acid 15-lipoxygenase products from human eosinophils. J Biol Chem, 257(12), 7068-76, 1982.

Feely, J, Heidemann, H, Gerkens, J, Roberts, L J, Branch, R A. Sodium depletion enhances nephrotoxicity of amphotericin B. Lancet, 1(8235), 1422-3, 1981.

Fitzgerald, G A, Maas, R L, Stein, R, Oates, J A, Roberts, L J. Intravenous prostacyclin in thrombotic thrombocytopenic purpura. Ann Intern Med, 95(3), 319-22, 1981.

Lewis, R A, Holgate, S T, Roberts, L J, Oates, J A, Austen, K F. Preferential generation of prostaglandin D2 by rat and human mast cells. Kroc Found Ser, 14, 239-54, 1981.

Roberts, L J, Sweetman, B J, Maas, R L, Hubbard, W C, Oates, J A. Clinical application of PG and TX metabolite quantification. Prog Lipid Res, 20, 117-21, 1981.

Roberts, L J, Sweetman, B J, Oates, J A. Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. J Biol Chem, 256(16), 8384-93, 1981.

Robertson, R M, Robertson, D, Roberts, L J, Maas, R L, FitzGerald, G A, Friesinger, G C, Oates, J A. Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. N Engl J Med, 304(17), 998-1003, 1981.

Bertagna, X Y, Bloomgarden, Z T, Rabin, D, Roberts, L J, Orth, D N. Molecular weight forms of immunoreactive calcitonin in a patient with medullary carcinoma of the thyroid: dynamic studies with calcium, pentagastrin and somatostatin. Clin Endocrinol (Oxf), 13(2), 115-23, 1980.

Holgate, S T, Lewis, R A, Maguire, J F, Roberts, L J, Oates, J A, Austen, K F. Effects of prostaglandin D2 on rat serosal mast cells: discordance between immunologic mediator release and cyclic AMP levels. J Immunol, 125(3), 1367-73, 1980.

Oates, J A, Roberts, L J, Sweetman, B J, Maas, R L, Gerkens, J F, Taber, D F. Metabolism of the prostaglandins and thromboxanes. Adv Prostaglandin Thromboxane Res, 6, 35-41, 1980.

Roberts, L J, Sweetman, B J, Lewis, R A, Austen, K F, Oates, J A. Increased production of prostaglandin D2 in patients with systemic mastocytosis. N Engl J Med, 303(24), 1400-4, 1980.

Roberts, L J, Sweetman, B J, Lewis, R A, Folarin, V F, Austen, K F, Oates, J A. Markedly increased synthesis of prostaglandin D2 in systemic mastocytosis. Trans Assoc Am Physicians, 93, 141-7, 1980.

Lewis, R A, Holgate, S T, Roberts, L J, Maguire, J F, Oates, J A, Austen, K F. Effects of indomethacin on cyclic nucleotide levels and histamine release from rat serosal mast cells. J Immunol, 123(4), 1663-8, 1979.

Roberts, L J, Hubbard, W C, Bloomgarden, Z T, Bertagna, X Y, McKenna, T J, Rabinowitz, D, Oates, J A. Prostaglandins: role in the humoral manifestations of medullary carcinoma of the thyroid and inhibition by somatostatin. Trans Assoc Am Physicians, 92, 286-91, 1979.

Roberts, L J, Lewis, R A, Oates, J A, Austen, K F. Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. Biochim Biophys Acta, 575(2), 185-92, 1979.

Roberts, L J, Marney, S R, Oates, J A. Blockade of the flush associated with metastatic gastric carcinoid by combined histamine H1 and H2 receptor antagonists. Evidence for an important role of H2 receptors in human vasculature. N Engl J Med, 300(5), 236-8, 1979.

Oelz, O, Knapp, H R, Roberts, L J, Oelz, R, Sweetman, B J, Oates, J A, Reed, P W. Calcium-dependent stimulation of thromboxane and prostaglandin biosynthesis by ionophores. Adv Prostaglandin Thromboxane Res, 3, 147-58, 1978.

Roberts, L J, Sweetman, B J, Oates, J A. Metabolism of thromboxane B2 in the monkey. J Biol Chem, 253(15), 5305-18, 1978.

Samuelsson, B, Hamberg, M, Roberts, L J, Oates, J A, Nelson, N A. Nomenclature for thromboxanes. Prostaglandins, 16(6), 857-60, 1978.

Duncan, G W, Roberts, L J, Wison, J P. Paroxysmal hypertensive hemicrania. Headache, 17(1), 5-6, 1977.

Knapp, H R, Oelz, O, Roberts, L J, Sweetman, B J, Oates, J A, Reed, P W. Ionophores stimulate prostaglandin and thromboxane biosynthesis. Proc Natl Acad Sci U S A, 74(10), 4251-5, 1977. PMCID:431917

Roberts, L J, Sweetman, B J, Morgan, J L, Payne, N A, Oates, J A. Identification of the major urinary metabolite of thromboxane B2 in the monkey. Prostaglandins, 13(4), 631-47, 1977.

Roberts, L J, Sweetman, B J, Payne, N A, Oates, J A. Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. J Biol Chem, 252(21), 7415-7, 1977.

Ellis, E F, Oelz, O, Roberts, L J, Payne, N A, Sweetman, B J, Nies, A S, Oates, J A. Coronary arterial smooth muscle contraction by a substance released from platelets: evidence that it is thromboxane A2. Science, 193(4258), 1135-7, 1976.

Wait, B, Blair, R, Roberts, L J. Energy intake of well-nourished children and adolescents. Am J Clin Nutr, 22(10), 1383-96, 1969.

Fern?!ndez, N A, Burgos, J C, Roberts, L J, Asenjo, C F. Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Montones 4, Las Piedras. J Am Diet Assoc, 53(2), 119-26, 1968.

Fern?!ndez, N A, Burgos, J C, Roberts, L J, Asenjo, C F. Nutritional status in Puerto Rican slum area. Am J Clin Nutr, 21(6), 646-56, 1968.

Fern?!ndez, N A, Burgos, J C, Roberts, L J, Asenjo, C F. Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Masas 2, Gurabo, Puerto Rico. Bol Asoc Med P R, 59(12), 503-14, 1967.

Fern?!ndez, N A, Burgos, J C, Plough, I C, Roberts, L J, Asenjo, C F. Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Naranjo, Moca, Puerto Rico. Am J Clin Nutr, 19(4), 269-84, 1966.

Fern?!ndez, NA, Burgos, JC, Plough, IC, Roberts, LJ, Asenjo, CF. Nutritional status of people in isolated areas of Puerto Rico. Survey of Barrio Mavilla, Vega Alta, Puerto Rico. Am J Clin Nutr, 17(5), 305-16, 1965.

ROBERTS, LJ. A COOPERATIVE NUTRITION RESEARCH PROGRAM FOR PUERTO RICO. I. BACKGROUND AND GENERAL PLAN. J Am Diet Assoc, 44, 18-21, 1964.

PLOUGH, IC, FERNANDEZLOPEZ, NA, ANGEL, CR, ROBERTS, LJ. A NUTRITION SURVEY OF THREE RURAL PUERTO RICAN COMMUNITIES. Bol Asoc Med P R, 55, SUPPL:1-51, 1963.

ROBERTS, LJ. Beginnings of the recommended dietary allowances. J Am Diet Assoc, 34(9), 903-8, 1958.

ROBERTS, LJ. A basic food pattern for Puerto Rico. J Am Diet Assoc, 30(11), 1097-100, 1954.

ROBERTS, LJ. A practical nutrition program for Puerto Rico. Nutr Rev, 8(11), 321-4, 1950.

King, CG, Eddy, WH, Heseltine, MM, Hunscher, HA, Mitchell, HS, Remington, RE, Roberts, LJ, Sebrell, WH, Sedgwick, J. Report of the Committee on Nutritional Problems (Nutrition as a Science in Wartime) : Food and Nutrition Section. Am J Public Health Nations Health, 34(7), 774-9, 1944. PMCID:1625091

Shepard, WP, Atwater, RM, Freeman, AW, Godfrey, ES, Gordon, JE, Hiscock, IV, McIver, P, Ramsey, GH, Smillie, WG, Tarbett, RE, Vaughan, HF, Baker, JN, Blood, AF, Dimond, B, Heseltine, MM, Koehne, M, Roberts, LJ, Sebrell, WH. Minimum Qualifications for Nutritionists in Health Agencies : Subcommittee on the Educational Qualifications of Public Health Nutritionists. Am J Public Health Nations Health, 31(5), 494-7, 1941. PMCID:1531421

Roberts, LJ. TEACHING CHILDREN TO LIKE WHOLESOME FOODS. Am J Public Health (N Y), 15(1), 52-3, 1925. PMCID:1320508


Postdoctoral Position Available
No

Postdoctoral Position Details
N/A

Updated Date
06/03/2009



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