Vanderbilt University School of Medicine

Brissova, Marcela , Ph.D.
Research Associate Professor of Medicine

Lab Url: N/A

Phone Number: 811-5496


Brissova, Marcela's picture

Office Address   Mailing Address

715 PRB 37232

Brissova, M, Shostak, A, Fligner, CL, Revetta, FL, Washington, MK, Powers, AC, Hull, RL. Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes. J Histochem Cytochem, 63(8), 637-45, 2015.

Burke, SJ, May, AL, Noland, RC, Lu, D, Brissova, M, Powers, AC, Sherrill, EM, Karlstad, MD, Campagna, SR, Stephens, JM, Collier, JJ. Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet ??-Cell Function. J Biol Chem, 290(21), 13401-16, 2015.

Kayton, NS, Poffenberger, G, Henske, J, Dai, C, Thompson, C, Aramandla, R, Shostak, A, Nicholson, W, Brissova, M, Bush, WS, Powers, AC. Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles. Am J Physiol Endocrinol Metab, 308(7), E592-602, 2015.

Zhu, X, Hu, R, Brissova, M, Stein, RW, Powers, AC, Gu, G, Kaverina, I. Microtubules Negatively Regulate Insulin Secretion in Pancreatic ?? Cells. Dev Cell, 34(6), 656-68, 2015.

Barnes, TM, Otero, YF, Elliott, AD, Locke, AD, Malabanan, CM, Coldren, AG, Brissova, M, Piston, DW, McGuinness, OP. Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas. Am J Physiol Endocrinol Metab, 307(10), E896-905, 2014.

Brissova, M, Aamodt, K, Brahmachary, P, Prasad, N, Hong, JY, Dai, C, Mellati, M, Shostak, A, Poffenberger, G, Aramandla, R, Levy, SE, Powers, AC. Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes ?? cell regeneration. Cell Metab, 19(3), 498-511, 2014.

Golson, ML, Bush, WS, Brissova, M. Automated quantification of pancreatic ??-cell mass. Am J Physiol Endocrinol Metab, 306(12), E1460-7, 2014.

Hang, Y, Yamamoto, T, Benninger, RK, Brissova, M, Guo, M, Bush, W, Piston, DW, Powers, AC, Magnuson, M, Thurmond, DC, Stein, R. The MafA transcription factor becomes essential to islet ??-cells soon after birth. Diabetes, 63(6), 1994-2005, 2014.

Pan, FC, Brissova, M. Pancreas development in humans. Curr Opin Endocrinol Diabetes Obes, 21(2), 77-82, 2014.

Reinert, RB, Cai, Q, Hong, JY, Plank, JL, Aamodt, K, Prasad, N, Aramandla, R, Dai, C, Levy, SE, Pozzi, A, Labosky, PA, Wright, CV, Brissova, M, Powers, AC. Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development, 141(7), 1480-91, 2014.

Dai, C, Brissova, M, Reinert, RB, Nyman, L, Liu, EH, Thompson, C, Shostak, A, Shiota, M, Takahashi, T, Powers, AC. Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis. Diabetes, 62(12), 4144-53, 2013.

Reinert, RB, Brissova, M, Shostak, A, Pan, FC, Poffenberger, G, Cai, Q, Hundemer, GL, Kantz, J, Thompson, CS, Dai, C, McGuinness, OP, Powers, AC. Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Diabetes, 62(12), 4154-64, 2013.

Cai, Q, Brissova, M, Reinert, RB, Pan, FC, Brahmachary, P, Jeansson, M, Shostak, A, Radhika, A, Poffenberger, G, Quaggin, SE, Jerome, WG, Dumont, DJ, Powers, AC. Enhanced expression of VEGF-A in ?? cells increases endothelial cell number but impairs islet morphogenesis and ?? cell proliferation. Dev Biol, 367(1), 40-54, 2012.

Dai, C, Brissova, M, Hang, Y, Thompson, C, Poffenberger, G, Shostak, A, Chen, Z, Stein, R, Powers, AC. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets. Diabetologia, 55(3), 707-18, 2012.

Reinert, RB, Kantz, J, Misfeldt, AA, Poffenberger, G, Gannon, M, Brissova, M, Powers, AC. Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice. PLoS One, 7(3), e33529, 2012.

Luther, JM, Luo, P, Kreger, MT, Brissova, M, Dai, C, Whitfield, TT, Kim, HS, Wasserman, DH, Powers, AC, Brown, NJ. Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets. Diabetologia, 54(8), 2152-63, 2011.

Zhao, A, Ohara-Imaizumi, M, Brissova, M, Benninger, RK, Xu, Y, Hao, Y, Abramowitz, J, Boulay, G, Powers, AC, Piston, D, Jiang, M, Nagamatsu, S, Birnbaumer, L, Gu, G. G??o represses insulin secretion by reducing vesicular docking in pancreatic beta-cells. Diabetes, 59(10), 2522-9, 2010.

Brissova, M, Powers, AC. Revascularization of transplanted islets: can it be improved. Diabetes, 57(9), 2269-71, 2008.

Nyman, LR, Wells, KS, Head, WS, McCaughey, M, Ford, E, Brissova, M, Piston, DW, Powers, AC. Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets. J Clin Invest, 118(11), 3790-7, 2008.

Virostko, J, Radhika, A, Poffenberger, G, Chen, Z, Brissova, M, Gilchrist, J, Coleman, B, Gannon, M, Jansen, ED, Powers, AC. Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation. Mol Imaging Biol, 12(1), 42-53, 2008.

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